GB1412187A - 6-5-nitro-2-furyl-pyrimidine derivatives methods for their preparation and compositions containing them - Google Patents
6-5-nitro-2-furyl-pyrimidine derivatives methods for their preparation and compositions containing themInfo
- Publication number
- GB1412187A GB1412187A GB3872573A GB3872573A GB1412187A GB 1412187 A GB1412187 A GB 1412187A GB 3872573 A GB3872573 A GB 3872573A GB 3872573 A GB3872573 A GB 3872573A GB 1412187 A GB1412187 A GB 1412187A
- Authority
- GB
- United Kingdom
- Prior art keywords
- furyl
- pyrimidine derivatives
- nitro
- preparation
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- GUCUYDRKRSDPEL-UHFFFAOYSA-N 5-(2-nitrofuran-3-yl)pyrimidine Chemical class [N+](=O)([O-])C=1OC=CC=1C=1C=NC=NC=1 GUCUYDRKRSDPEL-UHFFFAOYSA-N 0.000 abstract 1
- -1 5-furyl Chemical group 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 230000000802 nitrating effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2240242A DE2240242A1 (de) | 1972-08-16 | 1972-08-16 | Neue nitrofuranverbindungen, verfahren zu deren herstellung und diese enthaltende arzneimittel |
| FR7330717A FR2241316B1 (enrdf_load_stackoverflow) | 1972-08-16 | 1973-08-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1412187A true GB1412187A (en) | 1975-10-29 |
Family
ID=25763710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3872573A Expired GB1412187A (en) | 1972-08-16 | 1973-08-16 | 6-5-nitro-2-furyl-pyrimidine derivatives methods for their preparation and compositions containing them |
Country Status (11)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55120386A (en) * | 1979-03-06 | 1980-09-16 | Fuji Electric Co Ltd | Control system for dc commutatorless motor |
-
1972
- 1972-08-16 DE DE2240242A patent/DE2240242A1/de active Pending
-
1973
- 1973-07-23 ZA ZA735014A patent/ZA735014B/xx unknown
- 1973-07-26 AU AU58554/73A patent/AU469309B2/en not_active Expired
- 1973-08-01 CA CA177,910A patent/CA983034A/en not_active Expired
- 1973-08-14 LU LU68225A patent/LU68225A1/xx unknown
- 1973-08-14 BE BE2052985A patent/BE803564A/xx unknown
- 1973-08-15 NL NL7311249A patent/NL7311249A/xx unknown
- 1973-08-16 AT AT716673A patent/AT322542B/de not_active IP Right Cessation
- 1973-08-16 JP JP48075856A patent/JPS4945081A/ja active Pending
- 1973-08-16 GB GB3872573A patent/GB1412187A/en not_active Expired
- 1973-08-24 FR FR7330717A patent/FR2241316B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU469309B2 (en) | 1976-02-12 |
| JPS4945081A (enrdf_load_stackoverflow) | 1974-04-27 |
| BE803564A (fr) | 1973-12-03 |
| CA983034A (en) | 1976-02-03 |
| FR2241316A1 (enrdf_load_stackoverflow) | 1975-03-21 |
| AT322542B (de) | 1975-05-26 |
| ZA735014B (en) | 1974-06-26 |
| LU68225A1 (enrdf_load_stackoverflow) | 1973-10-23 |
| DE2240242A1 (de) | 1974-02-28 |
| FR2241316B1 (enrdf_load_stackoverflow) | 1976-10-22 |
| AU5855473A (en) | 1975-01-30 |
| NL7311249A (enrdf_load_stackoverflow) | 1974-02-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |