GB1405246A - Potentiated antimicrobial compositions - Google Patents
Potentiated antimicrobial compositionsInfo
- Publication number
- GB1405246A GB1405246A GB3581772A GB3581772A GB1405246A GB 1405246 A GB1405246 A GB 1405246A GB 3581772 A GB3581772 A GB 3581772A GB 3581772 A GB3581772 A GB 3581772A GB 1405246 A GB1405246 A GB 1405246A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aug
- alkyl
- optionally substituted
- competitor
- specified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000000845 anti-microbial effect Effects 0.000 title 1
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- BYIRZDTVVMWWFI-UHFFFAOYSA-N 2h-pteridin-1-ylmethanol Chemical compound C1=CN=C2N(CO)CN=CC2=N1 BYIRZDTVVMWWFI-UHFFFAOYSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 108010022394 Threonine synthase Proteins 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229960004050 aminobenzoic acid Drugs 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- LDBTVAXGKYIFHO-UHFFFAOYSA-N diaveridine Chemical compound C1=C(OC)C(OC)=CC=C1CC1=CN=C(N)N=C1N LDBTVAXGKYIFHO-UHFFFAOYSA-N 0.000 abstract 1
- 229950000246 diaveridine Drugs 0.000 abstract 1
- 102000004419 dihydrofolate reductase Human genes 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- CPNGPNLZQNNVQM-UHFFFAOYSA-N pteridine Chemical compound N1=CN=CC2=NC=CN=C21 CPNGPNLZQNNVQM-UHFFFAOYSA-N 0.000 abstract 1
- WKSAUQYGYAYLPV-UHFFFAOYSA-N pyrimethamine Chemical compound CCC1=NC(N)=NC(N)=C1C1=CC=C(Cl)C=C1 WKSAUQYGYAYLPV-UHFFFAOYSA-N 0.000 abstract 1
- 229960000611 pyrimethamine Drugs 0.000 abstract 1
- YAAWASYJIRZXSZ-UHFFFAOYSA-N pyrimidine-2,4-diamine Chemical class NC1=CC=NC(N)=N1 YAAWASYJIRZXSZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 abstract 1
- 229960001082 trimethoprim Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Fodder In General (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE787236D BE787236A (fr) | 1971-08-05 | Compositions de potentialisation | |
| GB3581772A GB1405246A (en) | 1971-08-05 | 1972-08-01 | Potentiated antimicrobial compositions |
| HUWE464A HU170534B (enrdf_load_stackoverflow) | 1971-08-05 | 1972-08-04 | |
| IT52002/72A IT1057861B (it) | 1971-08-05 | 1972-08-04 | Composizione per la diagnosi ed il trattamento di infezioni microbiche |
| JP47078240A JPS6036409B2 (ja) | 1971-08-05 | 1972-08-04 | 微生物感染処置用組成物 |
| CS5448A CS172956B2 (enrdf_load_stackoverflow) | 1971-08-05 | 1972-08-04 | |
| IE1103/72A IE36867B1 (en) | 1971-08-05 | 1972-08-04 | Potentiated antimicrobial compositions |
| NO2781/72A NO139004C (no) | 1971-08-05 | 1972-08-04 | Preparat for proeving og bestemmelse av protozoelle og bakterielle infeksjoner |
| NL7210719A NL7210719A (enrdf_load_stackoverflow) | 1971-08-05 | 1972-08-04 | |
| IL40050A IL40050A (en) | 1971-08-05 | 1972-08-04 | Compositions for treating microbial infections containing piperidine derivatives |
| SE7210162A SE434337B (sv) | 1971-08-05 | 1972-08-04 | Forfarande for framstellning av en farmaceutisk komposition med synergistiska egenskaper for anvendning vid behandling av infektioner fororsakade av mikroorganismer |
| DE2238536A DE2238536C2 (de) | 1971-08-05 | 1972-08-04 | Zubereitungen zur Behandlung von Mikrobeninfektionen |
| FR7228236A FR2150733B1 (enrdf_load_stackoverflow) | 1971-08-05 | 1972-08-04 | |
| LU65857A LU65857A1 (enrdf_load_stackoverflow) | 1971-08-05 | 1972-08-04 | |
| CA148,837A CA1007566A (en) | 1971-08-05 | 1972-08-04 | Potentiating formulations |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3677471 | 1971-08-05 | ||
| GB3581772A GB1405246A (en) | 1971-08-05 | 1972-08-01 | Potentiated antimicrobial compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1405246A true GB1405246A (en) | 1975-09-10 |
Family
ID=26262869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3581772A Expired GB1405246A (en) | 1971-08-05 | 1972-08-01 | Potentiated antimicrobial compositions |
Country Status (14)
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2400218A1 (de) * | 1973-01-05 | 1974-07-18 | Wellcome Found | Pharmazeutische formulierungen |
| DE2816064A1 (de) * | 1977-04-14 | 1978-10-19 | Wellcome Found | Veterinaermedizinische zubereitung zur behandlung von bakteriellen und protozoen-erkrankungen bei gefluegel |
| EP0108890B1 (en) * | 1982-09-20 | 1988-12-07 | The Wellcome Foundation Limited | Pharmaceutically active pteridine derivatives |
| CN113897413A (zh) * | 2021-10-12 | 2022-01-07 | 广州达安基因股份有限公司 | 一种体外诊断试剂防腐剂及其用途 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1451043A (en) * | 1972-08-01 | 1976-09-29 | Wellcome Found | Biologicylly acitve compounds and compositions |
| GB1454165A (en) * | 1972-08-01 | 1976-10-27 | Wellcome Found | Biologically active compounds and compositions |
| JPS63121616U (enrdf_load_stackoverflow) * | 1987-01-30 | 1988-08-08 |
-
0
- BE BE787236D patent/BE787236A/xx not_active IP Right Cessation
-
1972
- 1972-08-01 GB GB3581772A patent/GB1405246A/en not_active Expired
- 1972-08-04 SE SE7210162A patent/SE434337B/xx unknown
- 1972-08-04 LU LU65857A patent/LU65857A1/xx unknown
- 1972-08-04 DE DE2238536A patent/DE2238536C2/de not_active Expired
- 1972-08-04 HU HUWE464A patent/HU170534B/hu unknown
- 1972-08-04 FR FR7228236A patent/FR2150733B1/fr not_active Expired
- 1972-08-04 JP JP47078240A patent/JPS6036409B2/ja not_active Expired
- 1972-08-04 IE IE1103/72A patent/IE36867B1/xx unknown
- 1972-08-04 IT IT52002/72A patent/IT1057861B/it active
- 1972-08-04 NO NO2781/72A patent/NO139004C/no unknown
- 1972-08-04 CS CS5448A patent/CS172956B2/cs unknown
- 1972-08-04 NL NL7210719A patent/NL7210719A/xx unknown
- 1972-08-04 IL IL40050A patent/IL40050A/en unknown
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2400218A1 (de) * | 1973-01-05 | 1974-07-18 | Wellcome Found | Pharmazeutische formulierungen |
| DE2816064A1 (de) * | 1977-04-14 | 1978-10-19 | Wellcome Found | Veterinaermedizinische zubereitung zur behandlung von bakteriellen und protozoen-erkrankungen bei gefluegel |
| EP0108890B1 (en) * | 1982-09-20 | 1988-12-07 | The Wellcome Foundation Limited | Pharmaceutically active pteridine derivatives |
| CN113897413A (zh) * | 2021-10-12 | 2022-01-07 | 广州达安基因股份有限公司 | 一种体外诊断试剂防腐剂及其用途 |
| WO2023060818A1 (zh) * | 2021-10-12 | 2023-04-20 | 广州达安基因股份有限公司 | 一种体外诊断试剂防腐剂及其用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| NO139004C (no) | 1978-12-20 |
| FR2150733A1 (enrdf_load_stackoverflow) | 1973-04-13 |
| IE36867L (en) | 1973-02-05 |
| CS172956B2 (enrdf_load_stackoverflow) | 1977-01-28 |
| DE2238536C2 (de) | 1984-11-29 |
| HU170534B (enrdf_load_stackoverflow) | 1977-06-28 |
| SE434337B (sv) | 1984-07-23 |
| IL40050A (en) | 1976-02-29 |
| IT1057861B (it) | 1982-03-30 |
| IL40050A0 (en) | 1972-10-29 |
| DE2238536A1 (de) | 1973-02-22 |
| NL7210719A (enrdf_load_stackoverflow) | 1973-02-07 |
| IE36867B1 (en) | 1977-03-16 |
| LU65857A1 (enrdf_load_stackoverflow) | 1973-02-01 |
| NO139004B (no) | 1978-09-11 |
| JPS4828610A (enrdf_load_stackoverflow) | 1973-04-16 |
| JPS6036409B2 (ja) | 1985-08-20 |
| BE787236A (fr) | 1973-02-05 |
| FR2150733B1 (enrdf_load_stackoverflow) | 1975-06-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |