GB1391081A - Optically active benzodiazepines - Google Patents
Optically active benzodiazepinesInfo
- Publication number
- GB1391081A GB1391081A GB1256772A GB1256772A GB1391081A GB 1391081 A GB1391081 A GB 1391081A GB 1256772 A GB1256772 A GB 1256772A GB 1256772 A GB1256772 A GB 1256772A GB 1391081 A GB1391081 A GB 1391081A
- Authority
- GB
- United Kingdom
- Prior art keywords
- optically active
- benzodiazepines
- march
- alkyl
- protecting group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940049706 benzodiazepine Drugs 0.000 title abstract 2
- 150000001557 benzodiazepines Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH386871A CH554349A (de) | 1971-03-17 | 1971-03-17 | Verfahren zur herstellung von optisch aktiven 1,3-dihydro-2h-1,4-benzodiazepin-2-onen. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1391081A true GB1391081A (en) | 1975-04-16 |
Family
ID=4265209
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1256772A Expired GB1391081A (en) | 1971-03-17 | 1972-03-17 | Optically active benzodiazepines |
| GB4955674A Expired GB1391082A (en) | 1971-03-17 | 1972-03-17 | Optically active amino benzophenones |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4955674A Expired GB1391082A (en) | 1971-03-17 | 1972-03-17 | Optically active amino benzophenones |
Country Status (16)
| Country | Link |
|---|---|
| AT (1) | AT327909B (cg-RX-API-DMAC7.html) |
| BE (1) | BE780892A (cg-RX-API-DMAC7.html) |
| CA (1) | CA992079A (cg-RX-API-DMAC7.html) |
| CH (1) | CH554349A (cg-RX-API-DMAC7.html) |
| DE (1) | DE2212526A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES400851A1 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2130342B1 (cg-RX-API-DMAC7.html) |
| GB (2) | GB1391081A (cg-RX-API-DMAC7.html) |
| HU (1) | HU165496B (cg-RX-API-DMAC7.html) |
| IL (2) | IL38991A (cg-RX-API-DMAC7.html) |
| NL (1) | NL7203536A (cg-RX-API-DMAC7.html) |
| NO (1) | NO137896C (cg-RX-API-DMAC7.html) |
| SE (1) | SE399887B (cg-RX-API-DMAC7.html) |
| SU (1) | SU453842A3 (cg-RX-API-DMAC7.html) |
| YU (1) | YU34882B (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA721845B (cg-RX-API-DMAC7.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001010846A3 (en) * | 1999-08-05 | 2001-11-08 | Igt Pharma Inc | 1,4-diazepine derivatives for the treatment of diseases related to the central nervous system |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH602672A5 (cg-RX-API-DMAC7.html) * | 1974-06-28 | 1978-07-31 | Hoffmann La Roche | |
| CH603655A5 (cg-RX-API-DMAC7.html) * | 1974-10-21 | 1978-08-31 | Hoffmann La Roche |
-
1971
- 1971-03-17 CH CH386871A patent/CH554349A/xx not_active IP Right Cessation
-
1972
- 1972-03-14 AT AT214972A patent/AT327909B/de not_active IP Right Cessation
- 1972-03-15 DE DE19722212526 patent/DE2212526A1/de active Pending
- 1972-03-16 ES ES72400851A patent/ES400851A1/es not_active Expired
- 1972-03-16 IL IL38991A patent/IL38991A/en unknown
- 1972-03-16 NO NO853/72A patent/NO137896C/no unknown
- 1972-03-16 CA CA137,294A patent/CA992079A/en not_active Expired
- 1972-03-16 FR FR7209250A patent/FR2130342B1/fr not_active Expired
- 1972-03-16 IL IL47123A patent/IL47123A/en unknown
- 1972-03-16 YU YU697/72A patent/YU34882B/xx unknown
- 1972-03-16 NL NL7203536A patent/NL7203536A/xx unknown
- 1972-03-17 GB GB1256772A patent/GB1391081A/en not_active Expired
- 1972-03-17 HU HUCA323A patent/HU165496B/hu unknown
- 1972-03-17 GB GB4955674A patent/GB1391082A/en not_active Expired
- 1972-03-17 BE BE780892A patent/BE780892A/xx unknown
- 1972-03-17 SE SE7203457A patent/SE399887B/xx unknown
- 1972-03-17 SU SU1761120A patent/SU453842A3/ru active
- 1972-03-17 ZA ZA721845A patent/ZA721845B/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001010846A3 (en) * | 1999-08-05 | 2001-11-08 | Igt Pharma Inc | 1,4-diazepine derivatives for the treatment of diseases related to the central nervous system |
Also Published As
| Publication number | Publication date |
|---|---|
| YU69772A (en) | 1979-10-31 |
| YU34882B (en) | 1980-04-30 |
| ES400851A1 (es) | 1975-01-16 |
| SU453842A3 (cg-RX-API-DMAC7.html) | 1974-12-15 |
| GB1391082A (en) | 1975-04-16 |
| FR2130342B1 (cg-RX-API-DMAC7.html) | 1977-01-14 |
| SE399887B (sv) | 1978-03-06 |
| FR2130342A1 (cg-RX-API-DMAC7.html) | 1972-11-03 |
| NO137896C (no) | 1978-05-16 |
| CA992079A (en) | 1976-06-29 |
| NO137896B (no) | 1978-02-06 |
| NL7203536A (cg-RX-API-DMAC7.html) | 1972-09-19 |
| IL38991A (en) | 1976-09-30 |
| CH554349A (de) | 1974-09-30 |
| DE2212526A1 (de) | 1972-09-21 |
| ATA214972A (de) | 1975-05-15 |
| IL47123A (en) | 1976-09-30 |
| IL38991A0 (en) | 1972-05-30 |
| AT327909B (de) | 1976-02-25 |
| BE780892A (fr) | 1972-07-17 |
| HU165496B (cg-RX-API-DMAC7.html) | 1974-09-28 |
| ZA721845B (en) | 1972-12-27 |
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| GB1290468A (cg-RX-API-DMAC7.html) | ||
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |