GB1385620A - Carbazoles - Google Patents

Carbazoles

Info

Publication number
GB1385620A
GB1385620A GB3496873A GB3496873A GB1385620A GB 1385620 A GB1385620 A GB 1385620A GB 3496873 A GB3496873 A GB 3496873A GB 3496873 A GB3496873 A GB 3496873A GB 1385620 A GB1385620 A GB 1385620A
Authority
GB
United Kingdom
Prior art keywords
amino
group
lower alkyl
formula
lower alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3496873A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1385620A publication Critical patent/GB1385620A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB3496873A 1972-07-24 1973-07-23 Carbazoles Expired GB1385620A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27414272A 1972-07-24 1972-07-24

Publications (1)

Publication Number Publication Date
GB1385620A true GB1385620A (en) 1975-02-26

Family

ID=23046965

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3496873A Expired GB1385620A (en) 1972-07-24 1973-07-23 Carbazoles

Country Status (26)

Country Link
JP (1) JPS5740144B2 (enExample)
KR (1) KR780000289B1 (enExample)
AR (1) AR205331A1 (enExample)
AT (1) AT325607B (enExample)
AU (1) AU475534B2 (enExample)
BE (1) BE802596A (enExample)
CA (1) CA1026348A (enExample)
CH (1) CH587819A5 (enExample)
DD (1) DD107681A5 (enExample)
DE (1) DE2337340C2 (enExample)
DK (1) DK138537B (enExample)
FI (1) FI59244C (enExample)
FR (1) FR2193611B1 (enExample)
GB (1) GB1385620A (enExample)
HK (1) HK49878A (enExample)
HU (1) HU167611B (enExample)
IE (1) IE37942B1 (enExample)
IL (1) IL42799A (enExample)
KE (1) KE2847A (enExample)
LU (1) LU68071A1 (enExample)
MY (1) MY7800315A (enExample)
NL (1) NL169877C (enExample)
NO (1) NO142865C (enExample)
SE (2) SE402283B (enExample)
SU (1) SU509220A3 (enExample)
ZA (1) ZA734047B (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0060445A1 (en) * 1981-03-12 1982-09-22 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Process for the resolution of racemates and lactone esters used in said process
EP0239306A2 (en) 1986-03-27 1987-09-30 Merck Frosst Canada Inc. Tetrahydrocarbazole esters
EP0304156A1 (en) * 1987-07-21 1989-02-22 Merck Frosst Canada Inc. Cyclohept b indolealkanoic acids
RU2182148C2 (ru) * 1998-06-16 2002-05-10 Пфайзер Продактс Инк. Способ очистки ди(с1-с6)алкилового сложного эфира (6-хлор-2-карбазолил)метилмалоновой кислоты
US7601856B2 (en) 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146542A (en) * 1978-06-12 1979-03-27 Hoffmann-La Roche Inc. Dihydrocarbazole acetic acid and esters thereof
US4150031A (en) * 1978-06-26 1979-04-17 Hoffmann-La Roche Inc. Hydroxy methyl carbazole acetic acid and esters
US4158007A (en) * 1978-08-21 1979-06-12 Hoffmann-La Roche Inc. Carbazole methyl malonates
JPS6040256U (ja) * 1983-08-25 1985-03-20 伊東　璋 容器類洗浄機
IL81325A (en) * 1986-01-23 1990-11-29 Merck Frosst Canada Inc Tetrahydrocarbazole 1-alkanoic acids and pharmaceutical compositions containing them
EP0307077A1 (en) * 1987-07-21 1989-03-15 Merck Frosst Canada Inc. Tetrahydrocarbazoles for the improvement of cyclosporin therapy
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
JP2004010601A (ja) * 2002-06-11 2004-01-15 Nippon Steel Chem Co Ltd インドール誘導体の製造方法及びそのための有用な中間体
AU2004206796A1 (en) 2003-01-14 2004-08-05 Merck & Co., Inc. Geminally di-substituted NSAID derivatives as Abeta 42 lowering agents
MXPA05011850A (es) * 2003-05-06 2006-05-25 Air Prod & Chem Almacen de hidrogeno reversible hidrogenado de los sustratros pi-conjugados.
CA2535497A1 (en) * 2003-08-15 2005-02-24 Universite Laval Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbazoles
US9447040B2 (en) * 2011-11-15 2016-09-20 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Tricyclic compounds, compositions comprising them and uses thereof
JP5940036B2 (ja) * 2013-10-08 2016-06-29 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ
JP7747621B2 (ja) * 2020-03-25 2025-10-01 Jnc株式会社 化合物、液晶組成物および液晶表示素子

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD70880A (enExample) *
US3580926A (en) * 1969-11-10 1971-05-25 Parke Davis & Co Carbazole-4-alkanoic acids and tetrahydrocarbazole-4-alkanoic acids
ZA715217B (en) * 1970-08-20 1972-04-26 Org Nv Anti-inflammatory preparations

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0060445A1 (en) * 1981-03-12 1982-09-22 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Process for the resolution of racemates and lactone esters used in said process
EP0239306A2 (en) 1986-03-27 1987-09-30 Merck Frosst Canada Inc. Tetrahydrocarbazole esters
EP0304156A1 (en) * 1987-07-21 1989-02-22 Merck Frosst Canada Inc. Cyclohept b indolealkanoic acids
RU2182148C2 (ru) * 1998-06-16 2002-05-10 Пфайзер Продактс Инк. Способ очистки ди(с1-с6)алкилового сложного эфира (6-хлор-2-карбазолил)метилмалоновой кислоты
US7601856B2 (en) 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators

Also Published As

Publication number Publication date
FR2193611A1 (enExample) 1974-02-22
DE2337340C2 (de) 1985-05-02
KE2847A (en) 1978-06-30
DK138537C (enExample) 1979-03-05
FR2193611B1 (enExample) 1976-05-14
JPS4943973A (enExample) 1974-04-25
AU475534B2 (en) 1976-08-26
NO142865B (no) 1980-07-28
ZA734047B (en) 1974-03-27
NO142865C (no) 1980-11-05
AU5839073A (en) 1975-01-23
JPS5740144B2 (enExample) 1982-08-25
HU167611B (enExample) 1975-11-28
SE402283B (sv) 1978-06-26
DK138537B (da) 1978-09-25
NL169877C (nl) 1982-09-01
ATA649773A (de) 1975-01-15
AR205331A1 (es) 1976-04-30
IE37942L (en) 1974-01-24
FI59244B (fi) 1981-03-31
KR780000289B1 (en) 1978-08-10
FI59244C (fi) 1981-07-10
SE7605813L (sv) 1976-05-21
IE37942B1 (en) 1977-11-23
DD107681A5 (enExample) 1974-08-12
IL42799A0 (en) 1973-10-25
NL169877B (nl) 1982-04-01
MY7800315A (en) 1978-12-31
CA1026348A (en) 1978-02-14
IL42799A (en) 1977-03-31
HK49878A (en) 1978-09-08
SU509220A3 (ru) 1976-03-30
AT325607B (de) 1975-10-27
CH587819A5 (enExample) 1977-05-13
NL7310275A (enExample) 1974-01-28
BE802596A (fr) 1974-01-21
DE2337340A1 (de) 1974-02-14
LU68071A1 (enExample) 1975-04-11

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PE20 Patent expired after termination of 20 years

Effective date: 19930722