GB1382887A - Thiazole-5-carboxylic acid esters - Google Patents
Thiazole-5-carboxylic acid estersInfo
- Publication number
- GB1382887A GB1382887A GB2789372A GB2789372A GB1382887A GB 1382887 A GB1382887 A GB 1382887A GB 2789372 A GB2789372 A GB 2789372A GB 2789372 A GB2789372 A GB 2789372A GB 1382887 A GB1382887 A GB 1382887A
- Authority
- GB
- United Kingdom
- Prior art keywords
- piperazinyl
- thiazole
- carboxylic acid
- acid esters
- june
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7121466A FR2141526B1 (fr) | 1971-06-14 | 1971-06-14 | |
FR7306847A FR2247243B2 (fr) | 1971-06-14 | 1973-02-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1382887A true GB1382887A (en) | 1975-02-05 |
Family
ID=26216449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2789372A Expired GB1382887A (en) | 1971-06-14 | 1972-06-14 | Thiazole-5-carboxylic acid esters |
Country Status (10)
Country | Link |
---|---|
US (1) | US3853875A (fr) |
JP (1) | JPS5519251A (fr) |
AT (1) | AT317895B (fr) |
BE (1) | BE784777A (fr) |
CA (1) | CA1001629A (fr) |
CH (1) | CH555362A (fr) |
FR (2) | FR2141526B1 (fr) |
GB (1) | GB1382887A (fr) |
NL (2) | NL176072C (fr) |
SE (1) | SE389673B (fr) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0032058A1 (fr) * | 1980-01-03 | 1981-07-15 | Fujisawa Pharmaceutical Co., Ltd. | Dérivés du thiazole, procédés pour leur préparation et compositions pharmaceutiques les contenant |
US4457936A (en) * | 1980-01-29 | 1984-07-03 | Hoechst Aktiengesellschaft | Use of hydroxyphenyl-thiazole-, -thiazoline- and -thiazolidine-carboxylic acids, for influencing the collagen metabolism |
US6521652B1 (en) | 1998-08-31 | 2003-02-18 | University Of Florida Research Foundation, Inc. | Thiazoline acid derivatives |
US6864270B2 (en) | 1998-09-21 | 2005-03-08 | University Of Florida Research Foundation, Inc. | Iron binding agents |
US8278458B2 (en) | 2005-04-04 | 2012-10-02 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
US8324397B2 (en) | 2007-03-15 | 2012-12-04 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
US8604216B2 (en) | 2003-09-09 | 2013-12-10 | University Of Florida Research Foundation, Inc. | Desferrithiocin derivatives and methods of use thereof |
US10010535B2 (en) | 2013-11-22 | 2018-07-03 | University Of Florida Research Foundation, Incorporated | Desferrithiocin analogs and uses thereof |
US10570104B2 (en) | 2015-04-27 | 2020-02-25 | University Of Florida Research Foundation, Incorporated | Metabolically programmed metal chelators and uses thereof |
US11931346B2 (en) | 2011-12-16 | 2024-03-19 | University Of Florida Research Foundation, Incorporated | Uses of 4′-desferrithiocin analogs |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4339617C2 (de) * | 1993-11-20 | 2003-06-05 | Vortex Gmbh Dt | Rückschlagventil für ein Brauchwasser-Zirkulationssystem |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3238203A (en) * | 1962-10-12 | 1966-03-01 | Olin Mathieson | Basic esters of n-alkenoylanthranilic acid |
FR2073284B1 (fr) * | 1969-12-23 | 1973-07-13 | Ferlux |
-
1971
- 1971-06-14 FR FR7121466A patent/FR2141526B1/fr not_active Expired
-
1972
- 1972-06-12 CH CH871872A patent/CH555362A/fr not_active IP Right Cessation
- 1972-06-13 SE SE7207750A patent/SE389673B/xx unknown
- 1972-06-13 CA CA144,628A patent/CA1001629A/fr not_active Expired
- 1972-06-13 BE BE784777A patent/BE784777A/fr not_active IP Right Cessation
- 1972-06-14 AT AT510672A patent/AT317895B/de not_active IP Right Cessation
- 1972-06-14 NL NLAANVRAGE7208138,A patent/NL176072C/xx not_active IP Right Cessation
- 1972-06-14 GB GB2789372A patent/GB1382887A/en not_active Expired
- 1972-06-14 US US00262785A patent/US3853875A/en not_active Expired - Lifetime
-
1973
- 1973-02-27 FR FR7306847A patent/FR2247243B2/fr not_active Expired
-
1979
- 1979-06-12 JP JP7313379A patent/JPS5519251A/ja active Pending
- 1979-11-13 NL NL7908300A patent/NL7908300A/nl active Search and Examination
Cited By (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4411900A (en) * | 1980-01-03 | 1983-10-25 | Fujisawa Pharmaceutical Co., Ltd. | Benzhydrylpiperozinyl thiazole derivatives and pharmaceutical composition comprising the same |
EP0032058A1 (fr) * | 1980-01-03 | 1981-07-15 | Fujisawa Pharmaceutical Co., Ltd. | Dérivés du thiazole, procédés pour leur préparation et compositions pharmaceutiques les contenant |
US4457936A (en) * | 1980-01-29 | 1984-07-03 | Hoechst Aktiengesellschaft | Use of hydroxyphenyl-thiazole-, -thiazoline- and -thiazolidine-carboxylic acids, for influencing the collagen metabolism |
US8008502B2 (en) | 1998-08-31 | 2011-08-30 | University Of Florida Research Foundation, Inc. | Thiazoline acid derivatives |
US6521652B1 (en) | 1998-08-31 | 2003-02-18 | University Of Florida Research Foundation, Inc. | Thiazoline acid derivatives |
US6525080B1 (en) | 1998-08-31 | 2003-02-25 | University Of Florida Research Foundation, Inc. | Thiazoline acid derivatives |
US6559315B1 (en) | 1998-08-31 | 2003-05-06 | University Of Florida Research Foundation, Inc. | Thiazoline acid derivatives |
USRE39132E1 (en) | 1998-08-31 | 2006-06-13 | University Of Florida, Research Foundation, Inc. | Thiazoline acid derivatives |
US7126004B2 (en) | 1998-08-31 | 2006-10-24 | University Of Florida Research Foundation, Inc. | Thiazoline acid derivatives |
US6864270B2 (en) | 1998-09-21 | 2005-03-08 | University Of Florida Research Foundation, Inc. | Iron binding agents |
US7879886B2 (en) | 1998-09-21 | 2011-02-01 | University Of Florida Research Foundation, Inc. | Iron binding agents |
US7144904B2 (en) | 1998-09-21 | 2006-12-05 | University Of Florida Research Foundation, Inc. | Iron binding agents |
US8604216B2 (en) | 2003-09-09 | 2013-12-10 | University Of Florida Research Foundation, Inc. | Desferrithiocin derivatives and methods of use thereof |
US8278458B2 (en) | 2005-04-04 | 2012-10-02 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
US8722899B2 (en) | 2005-04-04 | 2014-05-13 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
US9096553B2 (en) | 2005-04-04 | 2015-08-04 | University Of Florida Research Foundation, Incorporated | Desferrithiocin polyether analogues |
US9567309B2 (en) | 2005-04-04 | 2017-02-14 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
US9994535B2 (en) | 2005-04-04 | 2018-06-12 | University Of Florida Foundation, Inc. | Desferrithiocin polyether analogues |
US8324397B2 (en) | 2007-03-15 | 2012-12-04 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
US9174948B2 (en) | 2007-03-15 | 2015-11-03 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
US9730917B2 (en) | 2007-03-15 | 2017-08-15 | University Of Florida Research Foundation, Incorporated | Desferrithiocin polyether analogues |
US11931346B2 (en) | 2011-12-16 | 2024-03-19 | University Of Florida Research Foundation, Incorporated | Uses of 4′-desferrithiocin analogs |
US10010535B2 (en) | 2013-11-22 | 2018-07-03 | University Of Florida Research Foundation, Incorporated | Desferrithiocin analogs and uses thereof |
US10570104B2 (en) | 2015-04-27 | 2020-02-25 | University Of Florida Research Foundation, Incorporated | Metabolically programmed metal chelators and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
FR2141526B1 (fr) | 1975-05-30 |
US3853875A (en) | 1974-12-10 |
FR2247243B2 (fr) | 1976-12-03 |
FR2141526A1 (fr) | 1973-01-26 |
NL7908300A (nl) | 1980-03-31 |
CA1001629A (fr) | 1976-12-14 |
DE2228805B2 (de) | 1977-03-31 |
AT317895B (de) | 1974-09-25 |
DE2228805A1 (de) | 1972-12-21 |
JPS5519251A (en) | 1980-02-09 |
NL7208138A (fr) | 1972-12-18 |
CH555362A (fr) | 1974-10-31 |
FR2247243A2 (fr) | 1975-05-09 |
NL176072C (nl) | 1985-02-18 |
NL176072B (nl) | 1984-09-17 |
BE784777A (fr) | 1972-12-13 |
SE389673B (sv) | 1976-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |