FR2247243B2 - - Google Patents

Info

Publication number
FR2247243B2
FR2247243B2 FR7306847A FR7306847A FR2247243B2 FR 2247243 B2 FR2247243 B2 FR 2247243B2 FR 7306847 A FR7306847 A FR 7306847A FR 7306847 A FR7306847 A FR 7306847A FR 2247243 B2 FR2247243 B2 FR 2247243B2
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7306847A
Other versions
FR2247243A2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR7121466A priority Critical patent/FR2141526B1/fr
Priority to CH871872A priority patent/CH555362A/fr
Priority to SE7207750A priority patent/SE389673B/xx
Priority to DE19722228805 priority patent/DE2228805C3/de
Priority to CA144,628A priority patent/CA1001629A/fr
Priority to BE784777A priority patent/BE784777A/fr
Priority to GB2789372A priority patent/GB1382887A/en
Priority to NLAANVRAGE7208138,A priority patent/NL176072C/xx
Priority to US00262785A priority patent/US3853875A/en
Priority to AT510672A priority patent/AT317895B/de
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7306847A priority patent/FR2247243B2/fr
Publication of FR2247243A2 publication Critical patent/FR2247243A2/fr
Application granted granted Critical
Publication of FR2247243B2 publication Critical patent/FR2247243B2/fr
Priority to JP7313379A priority patent/JPS5519251A/ja
Priority to NL7908300A priority patent/NL7908300A/nl
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR7306847A 1971-06-14 1973-02-27 Expired FR2247243B2 (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR7121466A FR2141526B1 (fr) 1971-06-14 1971-06-14
CH871872A CH555362A (fr) 1971-06-14 1972-06-12 Procede de preparation de nouveaux esters de l'acide 2-alcoyl thiazole 5-carboxylique.
CA144,628A CA1001629A (fr) 1971-06-14 1972-06-13 Procede de preparation de nouveaux esters de l'acide 2-alcoylthiazol 5-carboxylique
BE784777A BE784777A (fr) 1971-06-14 1972-06-13 Nouveaux esters de l'acide 2-alcoyl thiazol 5-carboxylique et procede de preparation
SE7207750A SE389673B (sv) 1971-06-14 1972-06-13 Sett att framstella nya estrar av 2-alkyltiazol-5-karbonsyra
DE19722228805 DE2228805C3 (de) 1971-06-14 1972-06-13 Substituierte Piperazinoäthylester der 2-Propylthiazol-5-carbonsäure, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen
GB2789372A GB1382887A (en) 1971-06-14 1972-06-14 Thiazole-5-carboxylic acid esters
NLAANVRAGE7208138,A NL176072C (nl) 1971-06-14 1972-06-14 Werkwijze ter bereiding van 2-alkyl 5-thiazool-carbonzuuresters, en van een geneesmiddel met vaatverwijdende werking; gevormd geneesmiddel.
US00262785A US3853875A (en) 1971-06-14 1972-06-14 Esters of 2-alkyl thiazole 5-carboxylic acid
AT510672A AT317895B (de) 1971-06-14 1972-06-14 Verfahren zur Herstellung neuer Ester der 2-Alkyl-thiazol-5-carbonsäure sowie deren Säureadditionssalzen
FR7306847A FR2247243B2 (fr) 1971-06-14 1973-02-27
JP7313379A JPS5519251A (en) 1971-06-14 1979-06-12 Manufacture of substituted piperazinoethanol
NL7908300A NL7908300A (nl) 1971-06-14 1979-11-13 Werkwijze voor de bereiding van nieuwe piperazino- -ethanol-verbindingen.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7121466A FR2141526B1 (fr) 1971-06-14 1971-06-14
FR7306847A FR2247243B2 (fr) 1971-06-14 1973-02-27

Publications (2)

Publication Number Publication Date
FR2247243A2 FR2247243A2 (fr) 1975-05-09
FR2247243B2 true FR2247243B2 (fr) 1976-12-03

Family

ID=26216449

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7121466A Expired FR2141526B1 (fr) 1971-06-14 1971-06-14
FR7306847A Expired FR2247243B2 (fr) 1971-06-14 1973-02-27

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7121466A Expired FR2141526B1 (fr) 1971-06-14 1971-06-14

Country Status (10)

Country Link
US (1) US3853875A (fr)
JP (1) JPS5519251A (fr)
AT (1) AT317895B (fr)
BE (1) BE784777A (fr)
CA (1) CA1001629A (fr)
CH (1) CH555362A (fr)
FR (2) FR2141526B1 (fr)
GB (1) GB1382887A (fr)
NL (2) NL176072C (fr)
SE (1) SE389673B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411900A (en) * 1980-01-03 1983-10-25 Fujisawa Pharmaceutical Co., Ltd. Benzhydrylpiperozinyl thiazole derivatives and pharmaceutical composition comprising the same
DE3002989A1 (de) * 1980-01-29 1981-07-30 Hoechst Ag, 6000 Frankfurt Hydroxyphenyl-thiazol, -thiazolin und -thiazolidin-carbonsaeuren, verfahren zu ihrer herstellung und ihre verwendung zur beeinflussung des kollagenstoffwechsels
DE4339617C2 (de) * 1993-11-20 2003-06-05 Vortex Gmbh Dt Rückschlagventil für ein Brauchwasser-Zirkulationssystem
US6083966A (en) 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
NZ526880A (en) 1998-09-21 2005-05-27 Univ Florida Antimalarial agents
AU2003270473A1 (en) 2003-09-09 2005-04-27 University Of Florida Desferrithiocin derivatives and their use as iron chelators
BRPI0610644B8 (pt) 2005-04-04 2021-05-25 Univ Florida composto e composição farmacêutica que compreende tal composto e um veículo ou diluente farmaceuticamente aceitável.
NZ579994A (en) 2007-03-15 2011-09-30 Univ Florida Desferrithiocin polyether analogues useful in the treatment of pathological conditions responsive to chelation or sequestration of trivalent metal
AU2012352025B2 (en) 2011-12-16 2018-01-18 University Of Florida Research Foundation, Inc. Uses of 4'-desferrithiocin analogs
EP3071201A4 (fr) 2013-11-22 2017-04-26 University of Florida Research Foundation, Inc. Analogues de la desferrithiocine et leurs utilisations
KR20170140306A (ko) 2015-04-27 2017-12-20 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 대사적으로 프로그램화된 금속 킬레이트화제 및 그의 용도

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238203A (en) * 1962-10-12 1966-03-01 Olin Mathieson Basic esters of n-alkenoylanthranilic acid
FR2073284B1 (fr) * 1969-12-23 1973-07-13 Ferlux

Also Published As

Publication number Publication date
NL7908300A (nl) 1980-03-31
NL176072C (nl) 1985-02-18
NL176072B (nl) 1984-09-17
GB1382887A (en) 1975-02-05
DE2228805B2 (de) 1977-03-31
BE784777A (fr) 1972-12-13
SE389673B (sv) 1976-11-15
NL7208138A (fr) 1972-12-18
DE2228805A1 (de) 1972-12-21
FR2141526A1 (fr) 1973-01-26
AT317895B (de) 1974-09-25
JPS5519251A (en) 1980-02-09
CA1001629A (fr) 1976-12-14
CH555362A (fr) 1974-10-31
FR2247243A2 (fr) 1975-05-09
US3853875A (en) 1974-12-10
FR2141526B1 (fr) 1975-05-30

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