GB1378241A - Amines and processes for their manufacture - Google Patents
Amines and processes for their manufactureInfo
- Publication number
- GB1378241A GB1378241A GB814172A GB814172A GB1378241A GB 1378241 A GB1378241 A GB 1378241A GB 814172 A GB814172 A GB 814172A GB 814172 A GB814172 A GB 814172A GB 1378241 A GB1378241 A GB 1378241A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- radical
- group
- converted
- propyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001412 amines Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 150000003254 radicals Chemical group 0.000 abstract 4
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- -1 3-methyl-5-oxazolidinyl Chemical group 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- KGMDODIDEQTIRA-UHFFFAOYSA-N 1,2-dihydrocyclobuta[a]anthracene Chemical class C1=CC2=CC3=CC=CC=C3C=C2C2=C1CC2 KGMDODIDEQTIRA-UHFFFAOYSA-N 0.000 abstract 1
- BTZRDVYVSRZQTE-UHFFFAOYSA-N 9 -(chlorocarbonylmethyl)-9,10-dihydro-9,10-ethano-anthracene Chemical compound C12=CC=CC=C2C2(CC(=O)Cl)C3=CC=CC=C3C1CC2 BTZRDVYVSRZQTE-UHFFFAOYSA-N 0.000 abstract 1
- IKHGUXGNUITLKF-UHFFFAOYSA-N Acetaldehyde Chemical class CC=O IKHGUXGNUITLKF-UHFFFAOYSA-N 0.000 abstract 1
- 229910010082 LiAlH Inorganic materials 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000003055 glycidyl group Chemical group C(C1CO1)* 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000001302 tertiary amino group Chemical group 0.000 abstract 1
- BPLKQGGAXWRFOE-UHFFFAOYSA-M trimethylsulfoxonium iodide Chemical compound [I-].C[S+](C)(C)=O BPLKQGGAXWRFOE-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH257871A CH548364A (de) | 1971-02-23 | 1971-02-23 | Verfahren zur herstellung neuer 9-(2-hydroxy-3-aminopropyl-9,10-dihydro-9,10-aethanoanthracene. |
| CH66972A CH561685A5 (en) | 1972-01-17 | 1972-01-17 | Substd 9-(2-hydroxy-3-aminoprop-1-enyl) -9,10-dihydro-9,10-ethano - anthracenes - antidepressants |
| AT335873A AT323726B (de) | 1971-02-23 | 1972-02-22 | Verfahren zur herstellung neuen 9-(2-hydroxy-3-aminopropyl-9,10-dihydro-9,10-äthanoanthracene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1378241A true GB1378241A (en) | 1974-12-27 |
Family
ID=32329363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB814172A Expired GB1378241A (en) | 1971-02-23 | 1972-02-22 | Amines and processes for their manufacture |
Country Status (17)
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL127069C (enrdf_load_stackoverflow) * | 1961-10-10 | |||
| US3706765A (en) * | 1969-01-03 | 1972-12-19 | Ciba Geigy Corp | Hydroxyethano-anthracenes |
| BE759571A (fr) * | 1969-11-28 | 1971-05-27 | Ciba Geigy | Nouvelles amines et procede pour leur preparation |
-
1972
- 1972-01-01 AR AR24066872A patent/AR204070A1/es active
- 1972-02-14 CA CA134,595A patent/CA993892A/en not_active Expired
- 1972-02-16 DE DE19722207097 patent/DE2207097C2/de not_active Expired
- 1972-02-18 SE SE199472A patent/SE387110B/xx unknown
- 1972-02-21 YU YU43172A patent/YU36288B/xx unknown
- 1972-02-21 AU AU39174/72A patent/AU476863B2/en not_active Expired
- 1972-02-21 ES ES400022A patent/ES400022A1/es not_active Expired
- 1972-02-22 NL NL7202326A patent/NL174826C/xx not_active IP Right Cessation
- 1972-02-22 BE BE779665A patent/BE779665A/xx not_active IP Right Cessation
- 1972-02-22 DK DK81872A patent/DK141508B/da not_active IP Right Cessation
- 1972-02-22 GB GB814172A patent/GB1378241A/en not_active Expired
- 1972-02-22 HU HUCI001211 patent/HU164585B/hu unknown
- 1972-02-23 JP JP47018166A patent/JPS5817740B1/ja active Granted
- 1972-02-23 FR FR7206115A patent/FR2126353B1/fr not_active Expired
-
1973
- 1973-01-01 AR AR24656873A patent/AR204309A1/es active
- 1973-02-19 AR AR24665873A patent/AR202178A1/es active
- 1973-02-19 AR AR24665773A patent/AR201551A1/es active
- 1973-11-19 AR AR15206373A patent/AR202284A1/es active
-
1977
- 1977-11-15 KE KE279577A patent/KE2795A/xx unknown
- 1977-12-08 HK HK61377A patent/HK61377A/xx unknown
-
1978
- 1978-12-30 MY MY7800117A patent/MY7800117A/xx unknown
-
1979
- 1979-06-18 YU YU143079A patent/YU40752B/xx unknown
- 1979-06-18 YU YU142979A patent/YU40843B/xx unknown
- 1979-06-18 YU YU143279A patent/YU41642B/xx unknown
- 1979-06-18 YU YU143179A patent/YU41867B/xx unknown
-
1980
- 1980-05-12 YU YU126180A patent/YU36363B/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |