GB1376713A - Process for the preparation of benzimidazol-2-yl-carbamic acid alkyl esters - Google Patents
Process for the preparation of benzimidazol-2-yl-carbamic acid alkyl estersInfo
- Publication number
- GB1376713A GB1376713A GB2746073A GB2746073A GB1376713A GB 1376713 A GB1376713 A GB 1376713A GB 2746073 A GB2746073 A GB 2746073A GB 2746073 A GB2746073 A GB 2746073A GB 1376713 A GB1376713 A GB 1376713A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- alkyl
- hydrogen
- benzimidazol
- carbamic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- JWYUFVNJZUSCSM-UHFFFAOYSA-N 2-aminobenzimidazole Chemical compound C1=CC=C2NC(N)=NC2=C1 JWYUFVNJZUSCSM-UHFFFAOYSA-N 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 1
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 235000013877 carbamide Nutrition 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000855 fungicidal effect Effects 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2227919A DE2227919C2 (de) | 1972-06-08 | 1972-06-08 | Verfahren zur Herstellung von Benzimidazol-2-yl-carbaminsäure-methylester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1376713A true GB1376713A (en) | 1974-12-11 |
Family
ID=5847182
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2746073A Expired GB1376713A (en) | 1972-06-08 | 1973-06-08 | Process for the preparation of benzimidazol-2-yl-carbamic acid alkyl esters |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3933846A (enExample) |
| BE (1) | BE800593A (enExample) |
| BR (1) | BR7304273D0 (enExample) |
| CH (1) | CH584691A5 (enExample) |
| DE (1) | DE2227919C2 (enExample) |
| FR (1) | FR2187786B1 (enExample) |
| GB (1) | GB1376713A (enExample) |
| IL (1) | IL42438A (enExample) |
| IT (1) | IT985327B (enExample) |
| NL (1) | NL7307824A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4299837A (en) | 1979-12-05 | 1981-11-10 | Montedison S.P.A. | Anthelmintic benzimidazole-carbamates |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2625391A1 (de) * | 1976-06-05 | 1977-12-15 | Bayer Ag | Mikrobizides mittel |
| US5276187A (en) * | 1991-08-23 | 1994-01-04 | Alliedsignal Inc. | Ketoxime carbonates and process for the synthesis of ketoxime carbonates generally |
| KR100314828B1 (ko) * | 1994-08-29 | 2002-02-19 | 유승렬 | 신규한벤즈이미다졸-2-카르바민산알킬에스터화합물및그의제조방법 |
| US6479526B1 (en) | 1995-04-12 | 2002-11-12 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of viruses and cancers |
| US6506783B1 (en) * | 1997-05-16 | 2003-01-14 | The Procter & Gamble Company | Cancer treatments and pharmaceutical compositions therefor |
| US6423734B1 (en) | 1999-08-13 | 2002-07-23 | The Procter & Gamble Company | Method of preventing cancer |
| US6380232B1 (en) * | 2000-09-26 | 2002-04-30 | The Procter & Gamble Company | Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof |
| US6608096B1 (en) * | 2000-09-26 | 2003-08-19 | University Of Arizona Foundation | Compounds and methods for use thereof in the treatment of cancer or viral infections |
| US6462062B1 (en) * | 2000-09-26 | 2002-10-08 | The Procter & Gamble Company | Compounds and methods for use thereof in the treatment of cancer or viral infections |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE122096C (enExample) * | ||||
| DE544211C (de) * | 1931-01-03 | 1932-02-17 | Hoffmann La Roche & Co Akt Ges | Verfahren zur Darstellung von disubstituierten Carbaminsaeureestern |
| DE676049C (de) * | 1934-08-05 | 1939-05-25 | Byk Guldenwerke Chem Fab Akt G | Verfahren zur Darstellung von Monourethanen der Alkylendiamine |
| US2041733A (en) * | 1934-11-03 | 1936-05-26 | Du Pont | Plastic composition |
| US2197479A (en) * | 1936-01-04 | 1940-04-16 | Du Pont | Carbamic acid esters of monoalkyl ethers of polyalkylene glycols |
| US3010968A (en) * | 1959-11-25 | 1961-11-28 | Du Pont | Process for manufacture of certain alkyl esters of benzimidazole carbamic acids |
| US3374265A (en) * | 1962-02-06 | 1968-03-19 | Armour Pharma | Diphenyl hydroxy carbamate compounds |
| IL28858A (en) * | 1966-11-15 | 1971-08-25 | Du Pont | Process for the preparation of 2-benzimidazole carbamic acid esters |
| DK131821C (da) * | 1967-03-22 | 1976-03-08 | Smith Kline French Lab | Analogifremgangsmade til fremstilling af en 2-karbalkoksyaminobenzimidazol |
| US3649674A (en) * | 1967-08-25 | 1972-03-14 | Schering Ag | Salts of carbamic and thiocarbamic esters with fungicidal and fungistatic action |
| DE1932297C3 (de) * | 1969-06-26 | 1974-09-12 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von Benzimidazol -2-carbaminsäureestern |
| US3763217A (en) * | 1970-12-03 | 1973-10-02 | Halcon International Inc | Preparation of carbamates |
-
1972
- 1972-06-08 DE DE2227919A patent/DE2227919C2/de not_active Expired
-
1973
- 1973-05-24 US US05/363,673 patent/US3933846A/en not_active Expired - Lifetime
- 1973-06-05 IL IL7342438A patent/IL42438A/en unknown
- 1973-06-05 NL NL7307824A patent/NL7307824A/xx unknown
- 1973-06-06 CH CH822473A patent/CH584691A5/xx not_active IP Right Cessation
- 1973-06-06 IT IT50469/73A patent/IT985327B/it active
- 1973-06-07 BR BR4273/73A patent/BR7304273D0/pt unknown
- 1973-06-07 BE BE131992A patent/BE800593A/xx not_active IP Right Cessation
- 1973-06-08 FR FR737320965A patent/FR2187786B1/fr not_active Expired
- 1973-06-08 GB GB2746073A patent/GB1376713A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4299837A (en) | 1979-12-05 | 1981-11-10 | Montedison S.P.A. | Anthelmintic benzimidazole-carbamates |
Also Published As
| Publication number | Publication date |
|---|---|
| IT985327B (it) | 1974-11-30 |
| BE800593A (fr) | 1973-12-07 |
| NL7307824A (enExample) | 1973-12-11 |
| FR2187786A1 (enExample) | 1974-01-18 |
| BR7304273D0 (pt) | 1974-06-27 |
| FR2187786B1 (enExample) | 1977-12-30 |
| DE2227919A1 (de) | 1973-12-20 |
| DE2227919C2 (de) | 1982-12-23 |
| CH584691A5 (enExample) | 1977-02-15 |
| US3933846A (en) | 1976-01-20 |
| IL42438A0 (en) | 1973-08-29 |
| IL42438A (en) | 1976-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 429A | Application made for amendment of specification (sect. 29/1949) | ||
| 429H | Application (made) for amendment of specification now open to opposition (sect. 29/1949) | ||
| 429D | Case decided by the comptroller ** specification amended (sect. 29/1949) |