IL42438A - The preparation of benzimidazol-2 yl carbamic acid alkyl esters - Google Patents
The preparation of benzimidazol-2 yl carbamic acid alkyl estersInfo
- Publication number
- IL42438A IL42438A IL7342438A IL4243873A IL42438A IL 42438 A IL42438 A IL 42438A IL 7342438 A IL7342438 A IL 7342438A IL 4243873 A IL4243873 A IL 4243873A IL 42438 A IL42438 A IL 42438A
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- formula
- compound
- process according
- admixture
- Prior art date
Links
- KXDHJXZQYSOELW-UHFFFAOYSA-N carbonic acid monoamide Natural products NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 229910052739 hydrogen Inorganic materials 0.000 claims 6
- 239000001257 hydrogen Substances 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- 239000003085 diluting agent Substances 0.000 claims 4
- 241000233866 Fungi Species 0.000 claims 3
- 125000003545 alkoxy group Chemical group 0.000 claims 3
- 125000004432 carbon atom Chemical group C* 0.000 claims 3
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 150000002367 halogens Chemical class 0.000 claims 3
- JWYUFVNJZUSCSM-UHFFFAOYSA-N 2-aminobenzimidazole Chemical compound C1=CC=C2NC(N)=NC2=C1 JWYUFVNJZUSCSM-UHFFFAOYSA-N 0.000 claims 2
- 241000238876 Acari Species 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 125000004429 atom Chemical group 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000000304 alkynyl group Chemical group 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 230000000855 fungicidal effect Effects 0.000 claims 1
- 239000012442 inert solvent Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2227919A DE2227919C2 (de) | 1972-06-08 | 1972-06-08 | Verfahren zur Herstellung von Benzimidazol-2-yl-carbaminsäure-methylester |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL42438A0 IL42438A0 (en) | 1973-08-29 |
| IL42438A true IL42438A (en) | 1976-03-31 |
Family
ID=5847182
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL7342438A IL42438A (en) | 1972-06-08 | 1973-06-05 | The preparation of benzimidazol-2 yl carbamic acid alkyl esters |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3933846A (enExample) |
| BE (1) | BE800593A (enExample) |
| BR (1) | BR7304273D0 (enExample) |
| CH (1) | CH584691A5 (enExample) |
| DE (1) | DE2227919C2 (enExample) |
| FR (1) | FR2187786B1 (enExample) |
| GB (1) | GB1376713A (enExample) |
| IL (1) | IL42438A (enExample) |
| IT (1) | IT985327B (enExample) |
| NL (1) | NL7307824A (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2625391A1 (de) * | 1976-06-05 | 1977-12-15 | Bayer Ag | Mikrobizides mittel |
| US4299837A (en) | 1979-12-05 | 1981-11-10 | Montedison S.P.A. | Anthelmintic benzimidazole-carbamates |
| US5276187A (en) * | 1991-08-23 | 1994-01-04 | Alliedsignal Inc. | Ketoxime carbonates and process for the synthesis of ketoxime carbonates generally |
| KR100314828B1 (ko) * | 1994-08-29 | 2002-02-19 | 유승렬 | 신규한벤즈이미다졸-2-카르바민산알킬에스터화합물및그의제조방법 |
| US6479526B1 (en) | 1995-04-12 | 2002-11-12 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of viruses and cancers |
| US6506783B1 (en) * | 1997-05-16 | 2003-01-14 | The Procter & Gamble Company | Cancer treatments and pharmaceutical compositions therefor |
| US6423734B1 (en) | 1999-08-13 | 2002-07-23 | The Procter & Gamble Company | Method of preventing cancer |
| US6380232B1 (en) * | 2000-09-26 | 2002-04-30 | The Procter & Gamble Company | Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof |
| US6608096B1 (en) * | 2000-09-26 | 2003-08-19 | University Of Arizona Foundation | Compounds and methods for use thereof in the treatment of cancer or viral infections |
| US6462062B1 (en) * | 2000-09-26 | 2002-10-08 | The Procter & Gamble Company | Compounds and methods for use thereof in the treatment of cancer or viral infections |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE122096C (enExample) * | ||||
| DE544211C (de) * | 1931-01-03 | 1932-02-17 | Hoffmann La Roche & Co Akt Ges | Verfahren zur Darstellung von disubstituierten Carbaminsaeureestern |
| DE676049C (de) * | 1934-08-05 | 1939-05-25 | Byk Guldenwerke Chem Fab Akt G | Verfahren zur Darstellung von Monourethanen der Alkylendiamine |
| US2041733A (en) * | 1934-11-03 | 1936-05-26 | Du Pont | Plastic composition |
| US2197479A (en) * | 1936-01-04 | 1940-04-16 | Du Pont | Carbamic acid esters of monoalkyl ethers of polyalkylene glycols |
| US3010968A (en) * | 1959-11-25 | 1961-11-28 | Du Pont | Process for manufacture of certain alkyl esters of benzimidazole carbamic acids |
| US3374265A (en) * | 1962-02-06 | 1968-03-19 | Armour Pharma | Diphenyl hydroxy carbamate compounds |
| IL28858A (en) * | 1966-11-15 | 1971-08-25 | Du Pont | Process for the preparation of 2-benzimidazole carbamic acid esters |
| DK131821C (da) * | 1967-03-22 | 1976-03-08 | Smith Kline French Lab | Analogifremgangsmade til fremstilling af en 2-karbalkoksyaminobenzimidazol |
| US3649674A (en) * | 1967-08-25 | 1972-03-14 | Schering Ag | Salts of carbamic and thiocarbamic esters with fungicidal and fungistatic action |
| DE1932297C3 (de) * | 1969-06-26 | 1974-09-12 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von Benzimidazol -2-carbaminsäureestern |
| US3763217A (en) * | 1970-12-03 | 1973-10-02 | Halcon International Inc | Preparation of carbamates |
-
1972
- 1972-06-08 DE DE2227919A patent/DE2227919C2/de not_active Expired
-
1973
- 1973-05-24 US US05/363,673 patent/US3933846A/en not_active Expired - Lifetime
- 1973-06-05 IL IL7342438A patent/IL42438A/en unknown
- 1973-06-05 NL NL7307824A patent/NL7307824A/xx unknown
- 1973-06-06 CH CH822473A patent/CH584691A5/xx not_active IP Right Cessation
- 1973-06-06 IT IT50469/73A patent/IT985327B/it active
- 1973-06-07 BR BR4273/73A patent/BR7304273D0/pt unknown
- 1973-06-07 BE BE131992A patent/BE800593A/xx not_active IP Right Cessation
- 1973-06-08 FR FR737320965A patent/FR2187786B1/fr not_active Expired
- 1973-06-08 GB GB2746073A patent/GB1376713A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1376713A (en) | 1974-12-11 |
| IT985327B (it) | 1974-11-30 |
| BE800593A (fr) | 1973-12-07 |
| NL7307824A (enExample) | 1973-12-11 |
| FR2187786A1 (enExample) | 1974-01-18 |
| BR7304273D0 (pt) | 1974-06-27 |
| FR2187786B1 (enExample) | 1977-12-30 |
| DE2227919A1 (de) | 1973-12-20 |
| DE2227919C2 (de) | 1982-12-23 |
| CH584691A5 (enExample) | 1977-02-15 |
| US3933846A (en) | 1976-01-20 |
| IL42438A0 (en) | 1973-08-29 |
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