GB1368049A - Purine derivative - Google Patents

Purine derivative

Info

Publication number
GB1368049A
GB1368049A GB1259673A GB1259673A GB1368049A GB 1368049 A GB1368049 A GB 1368049A GB 1259673 A GB1259673 A GB 1259673A GB 1259673 A GB1259673 A GB 1259673A GB 1368049 A GB1368049 A GB 1368049A
Authority
GB
United Kingdom
Prior art keywords
methylpurine
dimethylamino
methylpurin
amino
purine derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1259673A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
V N I KHIMIKOFARMATSEVTICHESKY
Original Assignee
V N I KHIMIKOFARMATSEVTICHESKY
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by V N I KHIMIKOFARMATSEVTICHESKY filed Critical V N I KHIMIKOFARMATSEVTICHESKY
Priority to GB1259673A priority Critical patent/GB1368049A/en
Publication of GB1368049A publication Critical patent/GB1368049A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/564—Three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1368049 Purine derivatives VSESOJUZNY NAUCHNO - ISSLEDOVATELSKY KHIMIKO - FARMATSEVTICHESKY INSTITUT IMENI S ORDZHONIKIDZE 15 March 1973 12596/73 Headings C2P and C2C The invention comprises p,p-bis-(1-aziridinyl)- N - [2 - (dimethylamino) - 7 - methylpurin - 6- yl]phosphinic amide (I) of formula and its preparation from theobromine (II) by the sequence II # 2,6-dichloro-7-methylpurine # 2 - chloro - 6 - amino - 7 - methylpurine # 2 - dimethylamino - 6 - amino - 7- methylpurine # N - [2 - (dimethylamino)- 7 - methylpurin - 6 - yl]phosphoramidic dichloride#I. Compound I is said to have cancerolytic, anti-tumour and anti-leukemic activities, and may be made up with carriers into pharmaceutical compositions for oral and parenteral administration.
GB1259673A 1973-03-15 1973-03-15 Purine derivative Expired GB1368049A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1259673A GB1368049A (en) 1973-03-15 1973-03-15 Purine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1259673A GB1368049A (en) 1973-03-15 1973-03-15 Purine derivative

Publications (1)

Publication Number Publication Date
GB1368049A true GB1368049A (en) 1974-09-25

Family

ID=10007563

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1259673A Expired GB1368049A (en) 1973-03-15 1973-03-15 Purine derivative

Country Status (1)

Country Link
GB (1) GB1368049A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147867A (en) * 1975-08-11 1979-04-03 Golovchinskaya Elena S 2-Dimethylamino-6-diethylenimidophosphamido-7-methyl-purine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147867A (en) * 1975-08-11 1979-04-03 Golovchinskaya Elena S 2-Dimethylamino-6-diethylenimidophosphamido-7-methyl-purine

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee