GB1357733A - 1,2,4-oxadiazole derivatives - Google Patents

1,2,4-oxadiazole derivatives

Info

Publication number
GB1357733A
GB1357733A GB1227270A GB1227270A GB1357733A GB 1357733 A GB1357733 A GB 1357733A GB 1227270 A GB1227270 A GB 1227270A GB 1227270 A GB1227270 A GB 1227270A GB 1357733 A GB1357733 A GB 1357733A
Authority
GB
United Kingdom
Prior art keywords
together form
pharmaceutical compositions
carbon bond
carbon
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1227270A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Priority to GB1227270A priority Critical patent/GB1357733A/en
Priority to DE19712137523 priority patent/DE2137523A1/en
Priority to FR7127409A priority patent/FR2100958B1/fr
Priority to NL7110316A priority patent/NL7110316A/xx
Priority to CH1107071A priority patent/CH579544A5/xx
Publication of GB1357733A publication Critical patent/GB1357733A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical

Abstract

1357733 Pharmaceutical compositions GLAXO LABORATORIES Ltd 10 Sept 1971 [28 July 1970] 12272/70 Heading A5B [Also in Division C2] Pharmaceutical compositions having antiparasitic, antimicrobial and antiviral activity, for oral, topical, rectal, vaginal or parenteral administration, comprise a compound of formula I: in which each of R<SP>1</SP> and R<SP>2</SP> is H, C 1-5 alkyl or halogen or R<SP>1</SP> and R<SP>2</SP> together form a carbon-carbon bond, R<SP>3</SP> is substituted phenyl, X and Y are both H or together form a nitrogen-carbon bond and R is a substituted or unsubstituted alkyl, aryl, alkenyl or alkynyl group, a primary, secondary or tertiary amino, acylamino, alkoxy, alkylthio, hydroxy, carboxy, carbalkoxy or hydrazino group or a halogen atom or a salt thereof, together with a pharmaceutical carrier or excipient. The compositions may also contain an anti-inflammatory agent, e.g. betamethasone-21-phosphate or an antibotic, e.g. tetracycline.
GB1227270A 1970-07-28 1970-07-28 1,2,4-oxadiazole derivatives Expired GB1357733A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB1227270A GB1357733A (en) 1970-07-28 1970-07-28 1,2,4-oxadiazole derivatives
DE19712137523 DE2137523A1 (en) 1970-07-28 1971-07-27 Oxadiazole derivatives
FR7127409A FR2100958B1 (en) 1970-07-28 1971-07-27
NL7110316A NL7110316A (en) 1970-07-28 1971-07-27
CH1107071A CH579544A5 (en) 1970-07-28 1971-07-27

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1227270A GB1357733A (en) 1970-07-28 1970-07-28 1,2,4-oxadiazole derivatives

Publications (1)

Publication Number Publication Date
GB1357733A true GB1357733A (en) 1974-06-26

Family

ID=10001510

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1227270A Expired GB1357733A (en) 1970-07-28 1970-07-28 1,2,4-oxadiazole derivatives

Country Status (5)

Country Link
CH (1) CH579544A5 (en)
DE (1) DE2137523A1 (en)
FR (1) FR2100958B1 (en)
GB (1) GB1357733A (en)
NL (1) NL7110316A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0492249A1 (en) * 1990-12-22 1992-07-01 Bayer Ag Use of substituted 1,2,4-oxadiazole derivatives for controlling endoparasites, new 1,2,4-oxadiazole derivatives and process for their preparation
WO1995019354A1 (en) * 1994-01-17 1995-07-20 Bayer Aktiengesellschaft 3-aryl alkenyl-1,2,4-oxadiazole derivatives and their use as parasiticides for animals

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1397073A (en) * 1971-05-19 1975-06-11 Glaxo Lab Ltd 1,2,4-oxadizoles

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0492249A1 (en) * 1990-12-22 1992-07-01 Bayer Ag Use of substituted 1,2,4-oxadiazole derivatives for controlling endoparasites, new 1,2,4-oxadiazole derivatives and process for their preparation
AU649086B2 (en) * 1990-12-22 1994-05-12 Bayer Animal Health Gmbh Use of substituted 1,2,4-oxadiazole derivatives for combating endoparasites, new substituted 1,2,4-oxadiazole derivatives, and processes for their preparation
US5371231A (en) * 1990-12-22 1994-12-06 Bayer Aktiengesellschaft Substituted 1,2,4-oxadiazole derivatives
US5585493A (en) * 1990-12-22 1996-12-17 Bayer Aktiengesellschaft Use of substituted 1,2,4-oxadiazole derivatives for combating endoparasites, new substituted 1,2,4-oxadiazole derivatives, and processes for their preparation
WO1995019354A1 (en) * 1994-01-17 1995-07-20 Bayer Aktiengesellschaft 3-aryl alkenyl-1,2,4-oxadiazole derivatives and their use as parasiticides for animals
AU698783B2 (en) * 1994-01-17 1998-11-05 Bayer Aktiengesellschaft 3-aryl-alkenyl-1,2,4-oxadiazole derivatives and their use for combating animal pests

Also Published As

Publication number Publication date
FR2100958A1 (en) 1972-03-24
FR2100958B1 (en) 1974-10-18
CH579544A5 (en) 1976-09-15
DE2137523A1 (en) 1972-02-03
NL7110316A (en) 1972-02-01

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees