GB1365455A - Imdazobensodiazepines - Google Patents
ImdazobensodiazepinesInfo
- Publication number
- GB1365455A GB1365455A GB4627872A GB4627872A GB1365455A GB 1365455 A GB1365455 A GB 1365455A GB 4627872 A GB4627872 A GB 4627872A GB 4627872 A GB4627872 A GB 4627872A GB 1365455 A GB1365455 A GB 1365455A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- imidazobenzodiazepines
- alkenyl
- prepared
- tranquillizers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- KLNFAMGHSZQYHR-UHFFFAOYSA-N imidazo[4,5-i][1,2]benzodiazepine Chemical class C1=CC=NN=C2C3=NC=NC3=CC=C21 KLNFAMGHSZQYHR-UHFFFAOYSA-N 0.000 abstract 2
- 125000006698 (C1-C3) dialkylamino group Chemical group 0.000 abstract 1
- 125000006705 (C5-C7) cycloalkyl group Chemical group 0.000 abstract 1
- UDLAUVFRZXIQJS-UHFFFAOYSA-N 1,3-dihydro-1,4-benzodiazepin-2-one Chemical compound N1C(=O)CN=CC2=CC=CC=C21 UDLAUVFRZXIQJS-UHFFFAOYSA-N 0.000 abstract 1
- -1 2-pyrimidyl Chemical group 0.000 abstract 1
- YPXQSGWOGQPLQO-UHFFFAOYSA-N 5-nitro-1,3-dihydrobenzimidazole-2-thione Chemical compound [O-][N+](=O)C1=CC=C2N=C(S)NC2=C1 YPXQSGWOGQPLQO-UHFFFAOYSA-N 0.000 abstract 1
- 101100188555 Arabidopsis thaliana OCT6 gene Proteins 0.000 abstract 1
- 101100037762 Caenorhabditis elegans rnh-2 gene Proteins 0.000 abstract 1
- KTLRWTOPTKGYQY-UHFFFAOYSA-N N-methyl-4-pyridone-3-carboxamide Chemical compound CN1C=CC(=O)C(C(N)=O)=C1 KTLRWTOPTKGYQY-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 239000003674 animal food additive Substances 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000003326 hypnotic agent Substances 0.000 abstract 1
- 230000000147 hypnotic effect Effects 0.000 abstract 1
- 244000144972 livestock Species 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008267 milk Substances 0.000 abstract 1
- 210000004080 milk Anatomy 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- CYQAYERJWZKYML-UHFFFAOYSA-N phosphorus pentasulfide Chemical compound S1P(S2)(=S)SP3(=S)SP1(=S)SP2(=S)S3 CYQAYERJWZKYML-UHFFFAOYSA-N 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19504971A | 1971-11-02 | 1971-11-02 | |
| US00364616A US3846443A (en) | 1971-11-02 | 1973-05-29 | 1H-IMIDAZO{8 1,2a{9 {8 1,4{9 BENZO-DIAZEPINE-1,2(3H)-DIONES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1365455A true GB1365455A (en) | 1974-09-04 |
Family
ID=26890656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4627872A Expired GB1365455A (en) | 1971-11-02 | 1972-10-06 | Imdazobensodiazepines |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3846443A (enrdf_load_stackoverflow) |
| JP (1) | JPS5545557B2 (enrdf_load_stackoverflow) |
| AU (1) | AU474359B2 (enrdf_load_stackoverflow) |
| BE (1) | BE790839A (enrdf_load_stackoverflow) |
| DE (1) | DE2252079A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2158414B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1365455A (enrdf_load_stackoverflow) |
| NL (1) | NL7214469A (enrdf_load_stackoverflow) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA755418B (en) * | 1974-09-11 | 1977-06-29 | Hoffmann La Roche | Diazepine derivatives |
| US4044142A (en) * | 1975-02-03 | 1977-08-23 | Roussel Uclaf | 1,2-Dihydro-6-phenyl-1H,4H-imidazobenzodiazepin-1-ones |
| US4134976A (en) * | 1975-02-15 | 1979-01-16 | Roussel Uclaf | 1,2-Dihydro-6-phenyl-1H,4H-imidazobenzodiazepin-1-ones |
| US4185102A (en) * | 1975-11-04 | 1980-01-22 | Roussel Uclaf | 1,2-Dihydro-6-phenyl-1H,4H-imidazobenzodiazepin-1-ones |
| DE3151597A1 (de) * | 1981-12-28 | 1983-07-07 | Kali-Chemie Pharma Gmbh, 3000 Hannover | (1,2)-anellierte 1,4-benzodiazepin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US4545935A (en) * | 1983-09-12 | 1985-10-08 | Iowa State University Research Foundation, Inc. | Amidoalkylation reactions of anilines |
| CA2504481A1 (en) * | 2002-10-30 | 2004-05-21 | Pointilliste, Inc. | Systems for capture and analysis of biological particles and methods using the systems |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1545214A (fr) * | 1966-11-23 | 1968-11-08 | Hoffmann La Roche | Procédé pour la préparation de dérivés de benzodiazépine |
| ZA713364B (en) * | 1970-06-18 | 1972-01-26 | Upjohn Co | Prganic compounds and process |
-
0
- BE BE790839D patent/BE790839A/xx not_active IP Right Cessation
-
1972
- 1972-10-06 GB GB4627872A patent/GB1365455A/en not_active Expired
- 1972-10-11 AU AU47634/72A patent/AU474359B2/en not_active Expired
- 1972-10-24 DE DE2252079A patent/DE2252079A1/de active Pending
- 1972-10-26 NL NL7214469A patent/NL7214469A/xx not_active Application Discontinuation
- 1972-10-28 JP JP10764472A patent/JPS5545557B2/ja not_active Expired
- 1972-10-31 FR FR7238639A patent/FR2158414B1/fr not_active Expired
-
1973
- 1973-05-29 US US00364616A patent/US3846443A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2158414A1 (enrdf_load_stackoverflow) | 1973-06-15 |
| FR2158414B1 (enrdf_load_stackoverflow) | 1977-01-14 |
| NL7214469A (enrdf_load_stackoverflow) | 1973-05-04 |
| AU474359B2 (en) | 1976-07-22 |
| BE790839A (fr) | 1973-04-30 |
| DE2252079A1 (de) | 1973-05-03 |
| JPS5545557B2 (enrdf_load_stackoverflow) | 1980-11-18 |
| US3846443A (en) | 1974-11-05 |
| JPS4856699A (enrdf_load_stackoverflow) | 1973-08-09 |
| AU4763472A (en) | 1974-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |