GB1357633A - Chromanone basic ether derivatives - Google Patents
Chromanone basic ether derivativesInfo
- Publication number
- GB1357633A GB1357633A GB585671A GB585671A GB1357633A GB 1357633 A GB1357633 A GB 1357633A GB 585671 A GB585671 A GB 585671A GB 585671 A GB585671 A GB 585671A GB 1357633 A GB1357633 A GB 1357633A
- Authority
- GB
- United Kingdom
- Prior art keywords
- groups
- alkyl
- formula
- group
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- MSTDXOZUKAQDRL-UHFFFAOYSA-N 4-Chromanone Chemical compound C1=CC=C2C(=O)CCOC2=C1 MSTDXOZUKAQDRL-UHFFFAOYSA-N 0.000 title abstract 2
- 150000002170 ethers Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000001033 ether group Chemical group 0.000 abstract 2
- 238000006266 etherification reaction Methods 0.000 abstract 2
- 150000002923 oximes Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 150000007659 semicarbazones Chemical class 0.000 abstract 2
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000005597 hydrazone group Chemical group 0.000 abstract 1
- 150000007857 hydrazones Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000005936 piperidyl group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB585671A GB1357633A (en) | 1971-03-02 | 1971-03-02 | Chromanone basic ether derivatives |
CA135,729A CA970369A (en) | 1971-03-02 | 1972-02-28 | Basic ethers derivatives of 4-chromanone |
NL7202578A NL7202578A (enrdf_load_stackoverflow) | 1971-03-02 | 1972-02-28 | |
FR7207017A FR2128454B1 (enrdf_load_stackoverflow) | 1971-03-02 | 1972-03-01 | |
DE19722209854 DE2209854A1 (de) | 1971-03-02 | 1972-03-01 | Chromanone, Verfahren zu ihrer Her stellung und diese Verbindungen enthaltende Arzneipraparate |
BE780137A BE780137A (fr) | 1971-03-02 | 1972-03-02 | Composes organiques bicycliques |
CH307872A CH577991A5 (enrdf_load_stackoverflow) | 1971-03-02 | 1972-03-02 | |
AU39589/72A AU456547B2 (en) | 1971-03-02 | 1972-03-02 | Chromanone basic ethers, methods for their preparation and compositions containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB585671A GB1357633A (en) | 1971-03-02 | 1971-03-02 | Chromanone basic ether derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1357633A true GB1357633A (en) | 1974-06-26 |
Family
ID=9803914
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB585671A Expired GB1357633A (en) | 1971-03-02 | 1971-03-02 | Chromanone basic ether derivatives |
Country Status (8)
Country | Link |
---|---|
AU (1) | AU456547B2 (enrdf_load_stackoverflow) |
BE (1) | BE780137A (enrdf_load_stackoverflow) |
CA (1) | CA970369A (enrdf_load_stackoverflow) |
CH (1) | CH577991A5 (enrdf_load_stackoverflow) |
DE (1) | DE2209854A1 (enrdf_load_stackoverflow) |
FR (1) | FR2128454B1 (enrdf_load_stackoverflow) |
GB (1) | GB1357633A (enrdf_load_stackoverflow) |
NL (1) | NL7202578A (enrdf_load_stackoverflow) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4080335A (en) * | 1975-07-28 | 1978-03-21 | Beecham Group Limited | Anorexic chromans |
US4148909A (en) * | 1974-07-30 | 1979-04-10 | Beecham Group Limited | Chromans to treat depression and reduce appetite |
US4167515A (en) * | 1974-07-30 | 1979-09-11 | Beecham Group Limited | Anorexic chromans |
USRE30739E (en) * | 1974-07-30 | 1981-09-08 | Beecham Group Limited | Anorexic chromans |
US4376123A (en) * | 1979-12-13 | 1983-03-08 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Hexahydroazepinyloxy-chromones useful as antidepressants |
EP0129636A1 (de) * | 1983-02-16 | 1985-01-02 | ALKALOIDA VEGYéSZETI GYáR | Neues Verfahren zur Herstellung von Chromen-Derivaten |
EP0424525B1 (en) * | 1987-12-11 | 1994-12-21 | Mitsui Petrochemical Industries, Ltd. | Novel amines and their use |
EP0864087A4 (en) * | 1995-11-03 | 1999-04-07 | Pharmacopeia Inc | COMBINATORIAL BANK OF DIHYDROBENZOPYRANES |
CN106905286A (zh) * | 2015-12-23 | 2017-06-30 | 江苏恩华药业股份有限公司 | 一种黄酮类化合物衍生物及其应用 |
US10266510B2 (en) | 2017-01-18 | 2019-04-23 | King Abdulaziz University | Antimicrobial and cytotoxic compounds and methods for treating cancer, a bacterial infection, and/or a fungal infection |
WO2021198283A1 (en) * | 2020-03-31 | 2021-10-07 | Janssen Pharmaceutica Nv | Inhibitors of antigen presentation by hla-dr |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH619701A5 (enrdf_load_stackoverflow) * | 1975-08-07 | 1980-10-15 | Bayer Ag | |
FI79535C (fi) * | 1982-05-06 | 1990-01-10 | Erba Farmitalia | Foerfarande foer framstaellning av dihydrobensopyrans och dihydrobensotiopyrans substituerade iminoderivat. |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1261111A (en) * | 1969-04-25 | 1972-01-19 | Science Union & Cie | New benzothiopyran derivatives and process for preparing them |
-
1971
- 1971-03-02 GB GB585671A patent/GB1357633A/en not_active Expired
-
1972
- 1972-02-28 CA CA135,729A patent/CA970369A/en not_active Expired
- 1972-02-28 NL NL7202578A patent/NL7202578A/xx unknown
- 1972-03-01 FR FR7207017A patent/FR2128454B1/fr not_active Expired
- 1972-03-01 DE DE19722209854 patent/DE2209854A1/de active Pending
- 1972-03-02 BE BE780137A patent/BE780137A/xx unknown
- 1972-03-02 AU AU39589/72A patent/AU456547B2/en not_active Expired
- 1972-03-02 CH CH307872A patent/CH577991A5/xx not_active IP Right Cessation
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4148909A (en) * | 1974-07-30 | 1979-04-10 | Beecham Group Limited | Chromans to treat depression and reduce appetite |
US4153617A (en) * | 1974-07-30 | 1979-05-08 | Beecham Group Limited | Anorexic chromans |
US4167515A (en) * | 1974-07-30 | 1979-09-11 | Beecham Group Limited | Anorexic chromans |
USRE30739E (en) * | 1974-07-30 | 1981-09-08 | Beecham Group Limited | Anorexic chromans |
US4080335A (en) * | 1975-07-28 | 1978-03-21 | Beecham Group Limited | Anorexic chromans |
US4780478A (en) * | 1979-12-13 | 1988-10-25 | Merck Patent Gesellschaft Mit Berschrankter Haftung | Aminopropoxy-chromones useful as antidepressants |
US4376123A (en) * | 1979-12-13 | 1983-03-08 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Hexahydroazepinyloxy-chromones useful as antidepressants |
US4508732A (en) * | 1979-12-13 | 1985-04-02 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Basic ethers useful as antidepressant agents |
EP0129636A1 (de) * | 1983-02-16 | 1985-01-02 | ALKALOIDA VEGYéSZETI GYáR | Neues Verfahren zur Herstellung von Chromen-Derivaten |
EP0424525B1 (en) * | 1987-12-11 | 1994-12-21 | Mitsui Petrochemical Industries, Ltd. | Novel amines and their use |
EP0864087A4 (en) * | 1995-11-03 | 1999-04-07 | Pharmacopeia Inc | COMBINATORIAL BANK OF DIHYDROBENZOPYRANES |
CN106905286A (zh) * | 2015-12-23 | 2017-06-30 | 江苏恩华药业股份有限公司 | 一种黄酮类化合物衍生物及其应用 |
CN106905286B (zh) * | 2015-12-23 | 2020-07-24 | 江苏恩华药业股份有限公司 | 一种黄酮类化合物衍生物及其应用 |
US10266510B2 (en) | 2017-01-18 | 2019-04-23 | King Abdulaziz University | Antimicrobial and cytotoxic compounds and methods for treating cancer, a bacterial infection, and/or a fungal infection |
WO2021198283A1 (en) * | 2020-03-31 | 2021-10-07 | Janssen Pharmaceutica Nv | Inhibitors of antigen presentation by hla-dr |
Also Published As
Publication number | Publication date |
---|---|
NL7202578A (enrdf_load_stackoverflow) | 1972-09-05 |
BE780137A (fr) | 1972-09-04 |
AU3958972A (en) | 1973-09-06 |
DE2209854A1 (de) | 1972-09-14 |
CA970369A (en) | 1975-07-01 |
CH577991A5 (enrdf_load_stackoverflow) | 1976-07-30 |
FR2128454B1 (enrdf_load_stackoverflow) | 1975-10-10 |
AU456547B2 (en) | 1974-12-04 |
FR2128454A1 (enrdf_load_stackoverflow) | 1972-10-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PLNP | Patent lapsed through nonpayment of renewal fees |