GB1357394A - 17-carboxyvinyl steroid glycosides and derivates thereof - Google Patents
17-carboxyvinyl steroid glycosides and derivates thereofInfo
- Publication number
- GB1357394A GB1357394A GB4993671A GB4993671A GB1357394A GB 1357394 A GB1357394 A GB 1357394A GB 4993671 A GB4993671 A GB 4993671A GB 4993671 A GB4993671 A GB 4993671A GB 1357394 A GB1357394 A GB 1357394A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- cardioactive
- oct
- alkyl
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930002534 steroid glycoside Natural products 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- -1 benzyloxy, benzyloxycarbonyloxy, trimethylsiloxy Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- JQWHASGSAFIOCM-UHFFFAOYSA-M sodium periodate Chemical compound [Na+].[O-]I(=O)(=O)=O JQWHASGSAFIOCM-UHFFFAOYSA-M 0.000 abstract 2
- QUQBOXYLXZAONE-DRPHTYIMSA-N 1-[(8R,9S,10S,13S,14S,17S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethane-1,2-diol Chemical class C[C@]12CC[C@H]3[C@@H](CCC4CCCC[C@]34C)[C@@H]1CC[C@@H]2C(O)CO QUQBOXYLXZAONE-DRPHTYIMSA-N 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000005161 aryl oxy carbonyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- KHIWWQKSHDUIBK-UHFFFAOYSA-N periodic acid Chemical compound OI(=O)(=O)=O KHIWWQKSHDUIBK-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 abstract 1
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/009—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by only one oxygen atom doubly bound
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702052634 DE2052634A1 (de) | 1970-10-27 | 1970-10-27 | Neue durch einen Steroidrest substi tuierte Derivate der Acrylsäure und Ver fahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1357394A true GB1357394A (en) | 1974-06-19 |
Family
ID=5786264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4993671A Expired GB1357394A (en) | 1970-10-27 | 1971-10-27 | 17-carboxyvinyl steroid glycosides and derivates thereof |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3752803A (en:Method) |
| AT (1) | AT306255B (en:Method) |
| AU (1) | AU462855B2 (en:Method) |
| BE (1) | BE774509A (en:Method) |
| CH (1) | CH565817A5 (en:Method) |
| DE (1) | DE2052634A1 (en:Method) |
| DK (1) | DK130309B (en:Method) |
| ES (1) | ES395530A1 (en:Method) |
| FR (1) | FR2111864B1 (en:Method) |
| GB (1) | GB1357394A (en:Method) |
| NL (1) | NL7114776A (en:Method) |
| SE (1) | SE372528B (en:Method) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2245726B2 (de) * | 1972-09-18 | 1979-01-18 | Dr. Karl Thomae Gmbh, 7950 Biberach | -androstan-17 ß -yl)-acrylnitril-3",4"-carbonat, Verfahren zu seiner Herstellung und diese enthaltende Arzneimittel |
| US3949074A (en) * | 1973-09-17 | 1976-04-06 | Boehringer Ingelheim Gmbh | Cardiotonic pharmaceutical compositions containing a cardiac glycoside and method of use |
| US4229441A (en) * | 1978-12-01 | 1980-10-21 | Merck & Co., Inc. | Immunologic adjuvant |
| US5144017A (en) * | 1988-07-13 | 1992-09-01 | University Of Manitoba | Compounds that bind to digitalis receptor |
-
1970
- 1970-10-27 DE DE19702052634 patent/DE2052634A1/de active Pending
-
1971
- 1971-09-29 ES ES395530A patent/ES395530A1/es not_active Expired
- 1971-10-18 US US00190279A patent/US3752803A/en not_active Expired - Lifetime
- 1971-10-22 CH CH1543471A patent/CH565817A5/xx not_active IP Right Cessation
- 1971-10-25 SE SE7113523A patent/SE372528B/xx unknown
- 1971-10-25 AU AU34940/71A patent/AU462855B2/en not_active Expired
- 1971-10-26 BE BE774509A patent/BE774509A/xx unknown
- 1971-10-26 DK DK520271AA patent/DK130309B/da unknown
- 1971-10-27 AT AT926371A patent/AT306255B/de not_active IP Right Cessation
- 1971-10-27 FR FR7138585A patent/FR2111864B1/fr not_active Expired
- 1971-10-27 GB GB4993671A patent/GB1357394A/en not_active Expired
- 1971-10-27 NL NL7114776A patent/NL7114776A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT306255B (de) | 1973-04-10 |
| SE372528B (en:Method) | 1974-12-23 |
| BE774509A (fr) | 1972-04-26 |
| DK130309B (da) | 1975-02-03 |
| AU462855B2 (en) | 1975-07-10 |
| DK130309C (en:Method) | 1975-06-30 |
| ES395530A1 (es) | 1973-12-01 |
| FR2111864A1 (en:Method) | 1972-06-09 |
| FR2111864B1 (en:Method) | 1975-10-10 |
| AU3494071A (en) | 1973-05-03 |
| US3752803A (en) | 1973-08-14 |
| CH565817A5 (en:Method) | 1975-08-29 |
| DE2052634A1 (de) | 1972-05-04 |
| NL7114776A (en:Method) | 1972-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |