GB1320362A - 21-phosphonoalkanoyloxy-pregnanes - Google Patents
21-phosphonoalkanoyloxy-pregnanesInfo
- Publication number
- GB1320362A GB1320362A GB5279472A GB5279470A GB1320362A GB 1320362 A GB1320362 A GB 1320362A GB 5279472 A GB5279472 A GB 5279472A GB 5279470 A GB5279470 A GB 5279470A GB 1320362 A GB1320362 A GB 1320362A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tetrahydropyran
- june
- alkyl
- formula
- phosphonoalkanoyloxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
1320362 Steroid phosphonic esters DR KARL THOMAE GmbH 10 June 1970 [10 June 1969] 52794/72 Divided out of 1320361 Heading C2U [Also in Division C3] The invention comprises compounds of formula wherein R<SP>1</SP> 1 is hydrogen, acyloxy, trialkylsiloxy, tetrahydropyran-2-yloxy or benzyloxy; R 3 is C 1-4 alkyl ; X is F, Cl, C 1-4 alkyl or C 1-4 alkoxy and A<SP>1</SP> is a group of formula wherein R<SP>1</SP> 2 is acyl, trialkylsilyl, tetrahydropyran-2-yl or benzyl. Preparation thereof is from the corresponding 21-hydroxysteroids (wherein R<SP>1</SP> 1 and R<SP>1</SP> 2 may additionally be OH and H respectively) by reaction with HO 2 C-CHX-PO(OR 3 ) 2 or a functional derivative thereof. When the starting material contains free hydroxyl group(s) in the 12-position or 3-sugar radical, these are also phosphonoacylated.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19691929427 DE1929427C (en) | 1969-06-10 | 22 Fluorocardohd glycosides and medicinal products containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1320362A true GB1320362A (en) | 1973-06-13 |
Family
ID=5736593
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2819670A Expired GB1320361A (en) | 1969-06-10 | 1970-06-10 | 22-substituted cardenolideglycosides |
GB5279472A Expired GB1320362A (en) | 1969-06-10 | 1970-06-10 | 21-phosphonoalkanoyloxy-pregnanes |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2819670A Expired GB1320361A (en) | 1969-06-10 | 1970-06-10 | 22-substituted cardenolideglycosides |
Country Status (16)
Country | Link |
---|---|
AT (1) | AT300205B (en) |
BE (1) | BE751768A (en) |
BG (1) | BG17306A3 (en) |
CH (1) | CH549563A (en) |
DK (1) | DK128900B (en) |
ES (1) | ES380440A1 (en) |
FI (1) | FI47182C (en) |
FR (1) | FR2052944B1 (en) |
GB (2) | GB1320361A (en) |
IE (1) | IE34292B1 (en) |
IL (1) | IL34690A (en) |
NL (1) | NL7008408A (en) |
PL (1) | PL81115B1 (en) |
RO (1) | RO58404A (en) |
SE (1) | SE360357B (en) |
ZA (1) | ZA703907B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE788669A (en) * | 1971-09-11 | 1973-03-12 | Thomae Gmbh Dr K | NEW CARDENOLIDE-GLUCOSIDES |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1013910A (en) * | 1962-11-28 | 1965-12-22 | Manuf De Produits Pharmaoeutiq | New derivative of gitoxin, the use and preparation thereof |
CH459190A (en) * | 1965-02-01 | 1968-07-15 | Sandoz Ag | Process for the production of a new cardenolide |
-
1970
- 1970-06-04 BG BG014854A patent/BG17306A3/en unknown
- 1970-06-05 ES ES380440A patent/ES380440A1/en not_active Expired
- 1970-06-05 RO RO63560A patent/RO58404A/ro unknown
- 1970-06-08 FI FI701616A patent/FI47182C/en active
- 1970-06-09 CH CH863270A patent/CH549563A/en not_active IP Right Cessation
- 1970-06-09 ZA ZA703907A patent/ZA703907B/en unknown
- 1970-06-09 AT AT518170A patent/AT300205B/en not_active IP Right Cessation
- 1970-06-09 IE IE749/70A patent/IE34292B1/en unknown
- 1970-06-09 IL IL34690A patent/IL34690A/en unknown
- 1970-06-09 PL PL1970141186A patent/PL81115B1/pl unknown
- 1970-06-09 FR FR7021111A patent/FR2052944B1/fr not_active Expired
- 1970-06-09 DK DK298770AA patent/DK128900B/en unknown
- 1970-06-10 GB GB2819670A patent/GB1320361A/en not_active Expired
- 1970-06-10 BE BE751768D patent/BE751768A/en unknown
- 1970-06-10 SE SE08079/70A patent/SE360357B/xx unknown
- 1970-06-10 NL NL7008408A patent/NL7008408A/xx unknown
- 1970-06-10 GB GB5279472A patent/GB1320362A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DK128900B (en) | 1974-07-22 |
CH549563A (en) | 1974-05-31 |
NL7008408A (en) | 1970-12-14 |
IL34690A0 (en) | 1970-08-19 |
AT300205B (en) | 1972-07-25 |
FI47182B (en) | 1973-07-02 |
FI47182C (en) | 1973-10-10 |
BG17306A3 (en) | 1973-07-25 |
IE34292B1 (en) | 1975-04-02 |
DE1929427A1 (en) | 1971-01-07 |
BE751768A (en) | 1970-12-10 |
IL34690A (en) | 1974-06-30 |
IE34292L (en) | 1970-12-19 |
SE360357B (en) | 1973-09-24 |
GB1320361A (en) | 1973-06-13 |
FR2052944A1 (en) | 1971-04-16 |
ZA703907B (en) | 1971-02-24 |
RO58404A (en) | 1975-09-15 |
ES380440A1 (en) | 1972-09-01 |
PL81115B1 (en) | 1975-08-30 |
FR2052944B1 (en) | 1974-08-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PLNP | Patent lapsed through nonpayment of renewal fees |