GB1315735A - Derivative of adenosine - Google Patents

Derivative of adenosine

Info

Publication number
GB1315735A
GB1315735A GB5134471A GB5134471A GB1315735A GB 1315735 A GB1315735 A GB 1315735A GB 5134471 A GB5134471 A GB 5134471A GB 5134471 A GB5134471 A GB 5134471A GB 1315735 A GB1315735 A GB 1315735A
Authority
GB
United Kingdom
Prior art keywords
triacetyl
nov
adenosine
derivative
chloroadenosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5134471A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1315735A publication Critical patent/GB1315735A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1315735 N(6) - (2,5 - dimethyl - benzyl) - 2- chloroadenosine BOEHRINGER MANNHEIM GmbH 4 Nov 1971 [10 Nov 1970] 51344/71 Heading C2C Novel compound of the formula is prepared by reacting triacetyl-2,6-dichloro-9- (#-D-ribofuranosyl)-purine with 2,5-dimethylbenzylamine in the presence of a weak base (preferably triethylamine) and subsequently saponifying the triacetyl groups preferably using ammoniacal alcohol. The above compound is active against atherosclerosis and with an adjuvant forms a pharmaceutical composition which may be administered orally or parenterally.
GB5134471A 1970-11-10 1971-11-04 Derivative of adenosine Expired GB1315735A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702055160 DE2055160A1 (en) 1970-11-10 1970-11-10 N (6M2,5-dimethylbenzyl) -2-chloradenosine

Publications (1)

Publication Number Publication Date
GB1315735A true GB1315735A (en) 1973-05-02

Family

ID=5787639

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5134471A Expired GB1315735A (en) 1970-11-10 1971-11-04 Derivative of adenosine

Country Status (12)

Country Link
AT (1) AT303976B (en)
CA (1) CA953715A (en)
CH (1) CH551424A (en)
DE (1) DE2055160A1 (en)
ES (1) ES396653A1 (en)
FR (1) FR2113889B1 (en)
GB (1) GB1315735A (en)
HU (1) HU164380B (en)
NL (1) NL7115188A (en)
SE (1) SE380026B (en)
SU (1) SU413678A3 (en)
ZA (1) ZA717391B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3406533A1 (en) * 1984-02-23 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim USE OF ADENOSINE DERIVATIVES AS ANTIALLERGICA AND MEDICINAL PRODUCTS CONTAINING THEM
CZ2009298A3 (en) * 2009-05-14 2010-11-24 Univerzita Palackého v Olomouci Substituted 6-benzylaminopurine ribosides, their use and pharmaceutical composition in which said compounds are comprised

Also Published As

Publication number Publication date
NL7115188A (en) 1972-05-15
CH551424A (en) 1974-07-15
AT303976B (en) 1972-12-27
CA953715A (en) 1974-08-27
DE2055160A1 (en) 1972-05-18
ES396653A1 (en) 1974-06-01
FR2113889B1 (en) 1975-06-06
ZA717391B (en) 1972-08-30
HU164380B (en) 1974-02-28
FR2113889A1 (en) 1972-06-30
SU413678A3 (en) 1974-01-30
SE380026B (en) 1975-10-27

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees