GB1338905A - Amino purine derivatives - Google Patents

Amino purine derivatives

Info

Publication number
GB1338905A
GB1338905A GB5450270A GB5450270A GB1338905A GB 1338905 A GB1338905 A GB 1338905A GB 5450270 A GB5450270 A GB 5450270A GB 5450270 A GB5450270 A GB 5450270A GB 1338905 A GB1338905 A GB 1338905A
Authority
GB
United Kingdom
Prior art keywords
amino
purine derivatives
amino purine
nov
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5450270A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of GB1338905A publication Critical patent/GB1338905A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

1338905 Antiviral compositions WELLCOME FOUNDATION Ltd 16 Nov 1970 [17 Nov 1969] 54502/70 Heading A5B [Also in Division C2] Pharmaceutical compositions useful as suppressors of the immune response and as antiviral agents comprise a compound I in which R<SP>1</SP> is amino or 1-4C alkylamino and R<SP>2</SP> is amino, provided that when R<SP>1</SP> is amino, R<SP>2</SP> is amino, and a suitable diluent or carrier. The compositions may be administered orally, rectally, topically or parenterally.
GB5450270A 1969-11-17 1970-11-16 Amino purine derivatives Expired GB1338905A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87744369A 1969-11-17 1969-11-17

Publications (1)

Publication Number Publication Date
GB1338905A true GB1338905A (en) 1973-11-28

Family

ID=25369972

Family Applications (2)

Application Number Title Priority Date Filing Date
GB5450270A Expired GB1338905A (en) 1969-11-17 1970-11-16 Amino purine derivatives
GB2751373A Expired GB1338906A (en) 1969-11-17 1970-11-16 Amino purine derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB2751373A Expired GB1338906A (en) 1969-11-17 1970-11-16 Amino purine derivatives

Country Status (26)

Country Link
US (1) US3666856A (en)
JP (1) JPS5429520B1 (en)
AT (1) AT309696B (en)
BE (1) BE759011A (en)
BR (1) BR6915136D0 (en)
CA (1) CA967564A (en)
CH (2) CH555344A (en)
CS (1) CS181701B2 (en)
DE (1) DE2056327C2 (en)
DK (1) DK128117B (en)
ES (2) ES385590A1 (en)
FI (1) FI54315C (en)
FR (1) FR2073364B1 (en)
GB (2) GB1338905A (en)
HU (1) HU163812B (en)
IE (1) IE34737B1 (en)
IL (1) IL35658A (en)
LU (1) LU62071A1 (en)
MC (1) MC869A1 (en)
NL (1) NL171589C (en)
NO (1) NO128156B (en)
PL (1) PL81167B1 (en)
SE (1) SE385374B (en)
YU (2) YU35033B (en)
ZA (1) ZA707722B (en)
ZM (1) ZM12970A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210745A (en) * 1978-01-04 1980-07-01 The United States Of America As Represented By The Department Of Health, Education And Welfare Procedure for the preparation of 9-β-D-arabinofuranosyl-2-fluoroadenine

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4081534A (en) * 1973-09-11 1978-03-28 Burroughs Wellcome Co. Amino purine nucleosides as autoimmune suppressant agents
GB1562899A (en) * 1975-06-17 1980-03-19 Wellcome Found Pharmaceutical compositions containing substituted 9-( -d-arabnofuranosyl)purine-5'-phosphate and salts thereof
DE3319282A1 (en) * 1983-05-27 1984-11-29 Gödecke AG, 1000 Berlin USE OF ADENOSINE IN THE TREATMENT OF HERPES
GB8712745D0 (en) * 1987-05-30 1987-07-01 Wellcome Found Antiviral compounds
JP3090456B2 (en) * 1988-03-16 2000-09-18 スクリップス クリニック アンド リサーチ ファウンデーション Substituted adenine derivatives useful as therapeutic agents
IE882585L (en) * 1988-08-25 1990-02-25 Prendergast Patrick T Viral treatment system
US5292725A (en) * 1988-08-25 1994-03-08 Prendergast Patrick T Administering particular compounds against various parasites, mycoplasmas, other indications and other infections
US5681941A (en) * 1990-01-11 1997-10-28 Isis Pharmaceuticals, Inc. Substituted purines and oligonucleotide cross-linking
US5308837A (en) * 1990-08-22 1994-05-03 Merrell Dow Pharmaceuticals Inc. 5'-amine substituted adenosine analogs as immunosuppressants
US6338963B1 (en) 1994-07-25 2002-01-15 Neotherapeutics, Inc. Use of carbon monoxide dependent guanylyl cyclase modifiers to stimulate neuritogenesis
US6232463B1 (en) 1997-10-09 2001-05-15 Isis Pharmaceuticals, Inc. Substituted purines and oligonucleotide cross-linking
AU3786299A (en) 1998-05-04 1999-11-23 Neotherapeutics, Inc. Novel serotonin-like 9-substituted hypoxanthine and methods of use
US6288069B1 (en) 1999-11-16 2001-09-11 Neotherapeutics, Inc. Use of 9-substituted hypoxanthine derivatives to stimulate regeneration of nervous tissue
US6407237B1 (en) 2001-02-21 2002-06-18 Neotherapeutics, Inc. Crystal forms of 9-substituted hypoxanthine derivatives
US6849735B1 (en) * 2000-06-23 2005-02-01 Merck Eprova Ag Methods of synthesis for 9-substituted hypoxanthine derivatives
WO2002004452A2 (en) 2000-07-07 2002-01-17 Neotherapeutics, Inc. Methods for treatment of disease-induced peripheral neuropathy and related conditions
US6759427B2 (en) * 2001-04-20 2004-07-06 Spectrum Pharmaceuticals, Inc. Synthesis and methods of use of tetrahydroindolone analogues and derivatives
US20030055249A1 (en) * 2001-07-17 2003-03-20 Fick David B. Synthesis and methods of use of pyrimidine analogues and derivatives
CN105237602B (en) * 2015-06-25 2018-05-18 新乡学院 A kind of preparation method of 2- amino arabinosy ladenosine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3208997A (en) * 1962-11-15 1965-09-28 Sankyo Co Process for preparing purine and pyrimidine nucleosides
US3407191A (en) * 1966-08-29 1968-10-22 Lilly Co Eli Adamantoate esters of nucleosides
JPH1097965A (en) * 1996-09-20 1998-04-14 Sony Corp Production control method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210745A (en) * 1978-01-04 1980-07-01 The United States Of America As Represented By The Department Of Health, Education And Welfare Procedure for the preparation of 9-β-D-arabinofuranosyl-2-fluoroadenine

Also Published As

Publication number Publication date
AT309696B (en) 1973-08-27
ZA707722B (en) 1972-06-28
IL35658A (en) 1974-10-22
DE2056327C2 (en) 1984-10-11
PL81167B1 (en) 1975-08-30
GB1338906A (en) 1973-11-28
DK128117B (en) 1974-03-04
LU62071A1 (en) 1971-08-12
CS181701B2 (en) 1978-03-31
ZM12970A1 (en) 1972-07-21
JPS5429520B1 (en) 1979-09-25
NL171589C (en) 1983-04-18
CA967564A (en) 1975-05-13
FR2073364B1 (en) 1974-03-22
HU163812B (en) 1973-10-27
FI54315C (en) 1978-11-10
NL171589B (en) 1982-11-16
FR2073364A1 (en) 1971-10-01
IE34737B1 (en) 1975-08-06
IE34737L (en) 1971-05-17
YU201978A (en) 1979-12-31
CH555833A (en) 1974-11-15
ES385590A1 (en) 1973-10-01
YU35034B (en) 1980-06-30
SE385374B (en) 1976-06-28
BR6915136D0 (en) 1973-04-19
US3666856A (en) 1972-05-30
DE2056327A1 (en) 1971-06-03
FI54315B (en) 1978-07-31
ES413787A1 (en) 1976-01-16
NL7016766A (en) 1971-05-19
NO128156B (en) 1973-10-08
CH555344A (en) 1974-10-31
YU280670A (en) 1979-12-31
MC869A1 (en) 1971-09-28
YU35033B (en) 1980-06-30
IL35658A0 (en) 1971-01-28
BE759011A (en) 1971-05-17

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee