GB1314955A - 4-4-alpha-hydroxybenzyl piperidino 4-fluorobutyrophenone derivative - Google Patents

4-4-alpha-hydroxybenzyl piperidino 4-fluorobutyrophenone derivative

Info

Publication number
GB1314955A
GB1314955A GB4994271A GB4994271A GB1314955A GB 1314955 A GB1314955 A GB 1314955A GB 4994271 A GB4994271 A GB 4994271A GB 4994271 A GB4994271 A GB 4994271A GB 1314955 A GB1314955 A GB 1314955A
Authority
GB
United Kingdom
Prior art keywords
phenyl
fluorobutyrophenone
followed
substituted
reduction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4994271A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Inc
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of GB1314955A publication Critical patent/GB1314955A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB4994271A 1970-11-27 1971-10-27 4-4-alpha-hydroxybenzyl piperidino 4-fluorobutyrophenone derivative Expired GB1314955A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9349570A 1970-11-27 1970-11-27

Publications (1)

Publication Number Publication Date
GB1314955A true GB1314955A (en) 1973-04-26

Family

ID=22239276

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4994271A Expired GB1314955A (en) 1970-11-27 1971-10-27 4-4-alpha-hydroxybenzyl piperidino 4-fluorobutyrophenone derivative

Country Status (16)

Country Link
JP (1) JPS5623985B2 (es)
BE (1) BE775593A (es)
CA (1) CA957376A (es)
CH (1) CH562215A5 (es)
DE (1) DE2158136C2 (es)
DK (1) DK135895B (es)
ES (1) ES397370A1 (es)
FR (1) FR2115451B1 (es)
GB (1) GB1314955A (es)
IE (1) IE35778B1 (es)
IL (1) IL38079A (es)
NL (1) NL175411C (es)
NO (1) NO135248C (es)
PH (1) PH9306A (es)
SE (1) SE369900B (es)
ZA (1) ZA717147B (es)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0208235A1 (en) * 1985-07-02 1987-01-14 Merrell Dow Pharmaceuticals Inc. N-Aralkyl piperidinemethanol derivatives
US4783471A (en) * 1985-07-02 1988-11-08 Merrell Dow Pharmaceuticals Inc. N-aralkyl piperidine methanol derivatives and the uses thereof
WO2006031764A2 (en) * 2004-09-13 2006-03-23 Bayer Cropscience Ag Processes for prepating n-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and intermediates

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7409245L (es) * 1973-07-19 1975-01-20 Robins Co Inc A H
US4246268A (en) * 1979-02-09 1981-01-20 Richardson-Merrell Inc. Neuroleptic-4-(naphthylmethyl)piperidine derivatives
IE49998B1 (en) * 1979-08-06 1986-01-22 Merrell Dow Pharma 4-(naphthalenyloxy)piperidine derivatives
US4283404A (en) * 1979-09-04 1981-08-11 Richardson-Merrell Inc. Aroylethenylpiperidinobutyrophenone antipsychotic agents
US4284636A (en) * 1979-09-04 1981-08-18 Richardson-Merrell Inc. Cinnamoylpiperidinobutyrophenone antipsychotic agents
ZA806501B (en) * 1979-10-27 1981-10-28 Richardson Merrell Inc 4-(4-alkyl-aroyl-1-piperidino)butyrophenone antipsychotic agents
IL117149A0 (en) * 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0208235A1 (en) * 1985-07-02 1987-01-14 Merrell Dow Pharmaceuticals Inc. N-Aralkyl piperidinemethanol derivatives
US4783471A (en) * 1985-07-02 1988-11-08 Merrell Dow Pharmaceuticals Inc. N-aralkyl piperidine methanol derivatives and the uses thereof
WO2006031764A2 (en) * 2004-09-13 2006-03-23 Bayer Cropscience Ag Processes for prepating n-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and intermediates
WO2006031764A3 (en) * 2004-09-13 2006-07-13 Fmc Corp Processes for prepating n-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and intermediates

Also Published As

Publication number Publication date
CA957376A (en) 1974-11-05
FR2115451B1 (es) 1975-02-07
BE775593A (fr) 1972-03-16
DK135895B (da) 1977-07-11
IL38079A0 (en) 1972-01-27
NO135248B (es) 1976-11-29
JPS5623985B2 (es) 1981-06-03
DE2158136A1 (de) 1972-05-31
FR2115451A1 (es) 1972-07-07
NL175411C (nl) 1984-11-01
NL175411B (nl) 1984-06-01
IL38079A (en) 1974-10-22
IE35778L (en) 1972-05-27
CH562215A5 (es) 1975-05-30
SE369900B (es) 1974-09-23
DE2158136C2 (de) 1982-11-18
DK135895C (es) 1977-12-12
NO135248C (es) 1977-03-09
ES397370A1 (es) 1974-05-16
ZA717147B (en) 1972-07-26
NL7116194A (es) 1972-05-30
PH9306A (en) 1975-08-18
IE35778B1 (en) 1976-05-26

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years