BE775593A - Derives de fluoro-4'((alpha-hydroxybenzyl)-4 piperidino) -4 butyrophenone et procede de leur preparation - Google Patents

Derives de fluoro-4'((alpha-hydroxybenzyl)-4 piperidino) -4 butyrophenone et procede de leur preparation

Info

Publication number
BE775593A
BE775593A BE775593A BE775593A BE775593A BE 775593 A BE775593 A BE 775593A BE 775593 A BE775593 A BE 775593A BE 775593 A BE775593 A BE 775593A BE 775593 A BE775593 A BE 775593A
Authority
BE
Belgium
Prior art keywords
butyrophenone
hydroxybenzyl
piperidino
fluoro
alpha
Prior art date
Application number
BE775593A
Other languages
English (en)
Inventor
A A Carr
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of BE775593A publication Critical patent/BE775593A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BE775593A 1970-11-27 1971-11-19 Derives de fluoro-4'((alpha-hydroxybenzyl)-4 piperidino) -4 butyrophenone et procede de leur preparation BE775593A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9349570A 1970-11-27 1970-11-27

Publications (1)

Publication Number Publication Date
BE775593A true BE775593A (fr) 1972-03-16

Family

ID=22239276

Family Applications (1)

Application Number Title Priority Date Filing Date
BE775593A BE775593A (fr) 1970-11-27 1971-11-19 Derives de fluoro-4'((alpha-hydroxybenzyl)-4 piperidino) -4 butyrophenone et procede de leur preparation

Country Status (16)

Country Link
JP (1) JPS5623985B2 (fr)
BE (1) BE775593A (fr)
CA (1) CA957376A (fr)
CH (1) CH562215A5 (fr)
DE (1) DE2158136C2 (fr)
DK (1) DK135895B (fr)
ES (1) ES397370A1 (fr)
FR (1) FR2115451B1 (fr)
GB (1) GB1314955A (fr)
IE (1) IE35778B1 (fr)
IL (1) IL38079A (fr)
NL (1) NL175411C (fr)
NO (1) NO135248C (fr)
PH (1) PH9306A (fr)
SE (1) SE369900B (fr)
ZA (1) ZA717147B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7409245L (fr) * 1973-07-19 1975-01-20 Robins Co Inc A H
US4246268A (en) * 1979-02-09 1981-01-20 Richardson-Merrell Inc. Neuroleptic-4-(naphthylmethyl)piperidine derivatives
IE49998B1 (en) * 1979-08-06 1986-01-22 Merrell Dow Pharma 4-(naphthalenyloxy)piperidine derivatives
US4284636A (en) * 1979-09-04 1981-08-18 Richardson-Merrell Inc. Cinnamoylpiperidinobutyrophenone antipsychotic agents
US4283404A (en) * 1979-09-04 1981-08-11 Richardson-Merrell Inc. Aroylethenylpiperidinobutyrophenone antipsychotic agents
ZA806501B (en) * 1979-10-27 1981-10-28 Richardson Merrell Inc 4-(4-alkyl-aroyl-1-piperidino)butyrophenone antipsychotic agents
CA1280421C (fr) * 1985-07-02 1991-02-19 Albert A. Carr Derives piperidinyl disubstitutes en 1,4
US4783471A (en) * 1985-07-02 1988-11-08 Merrell Dow Pharmaceuticals Inc. N-aralkyl piperidine methanol derivatives and the uses thereof
IL117149A0 (en) * 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists
AR052977A1 (es) * 2004-09-13 2007-04-18 Fmc Corp Procesos para preparar n-(arilmetil sustituido)-4-(metil disustituido)piperidinas e intermediarios

Also Published As

Publication number Publication date
IE35778L (en) 1972-05-27
NL175411B (nl) 1984-06-01
PH9306A (en) 1975-08-18
NO135248B (fr) 1976-11-29
DE2158136A1 (de) 1972-05-31
NL175411C (nl) 1984-11-01
DK135895B (da) 1977-07-11
JPS5623985B2 (fr) 1981-06-03
FR2115451A1 (fr) 1972-07-07
CA957376A (en) 1974-11-05
DK135895C (fr) 1977-12-12
NL7116194A (fr) 1972-05-30
NO135248C (fr) 1977-03-09
GB1314955A (en) 1973-04-26
IE35778B1 (en) 1976-05-26
IL38079A (en) 1974-10-22
ZA717147B (en) 1972-07-26
FR2115451B1 (fr) 1975-02-07
ES397370A1 (es) 1974-05-16
SE369900B (fr) 1974-09-23
DE2158136C2 (de) 1982-11-18
IL38079A0 (en) 1972-01-27
CH562215A5 (fr) 1975-05-30

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: RICHARDSON MERRELL INC.

Effective date: 19911119