GB1313219A - Process for the preparation of compound having a 2,3,5,6-tetrahydro- imidazo 2,1-b thiazole ring system - Google Patents
Process for the preparation of compound having a 2,3,5,6-tetrahydro- imidazo 2,1-b thiazole ring systemInfo
- Publication number
- GB1313219A GB1313219A GB3483770A GB3483770A GB1313219A GB 1313219 A GB1313219 A GB 1313219A GB 3483770 A GB3483770 A GB 3483770A GB 3483770 A GB3483770 A GB 3483770A GB 1313219 A GB1313219 A GB 1313219A
- Authority
- GB
- United Kingdom
- Prior art keywords
- preparation
- thiazolidine
- imino
- compound
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical group C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 4
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- SGJVENMTWFTZOJ-UHFFFAOYSA-N 1-bromo-2-isothiocyanatoethane Chemical compound BrCCN=C=S SGJVENMTWFTZOJ-UHFFFAOYSA-N 0.000 abstract 1
- NGKOCETVOBCCII-UHFFFAOYSA-N 2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole Chemical class C1CN=C2SCCN21 NGKOCETVOBCCII-UHFFFAOYSA-N 0.000 abstract 1
- NTVOLTHVRHHPCS-UHFFFAOYSA-N 2-(4-amino-2,5-dihydro-1,3-thiazol-2-yl)ethanol Chemical compound OCCC1SCC(N1)=N NTVOLTHVRHHPCS-UHFFFAOYSA-N 0.000 abstract 1
- IJXJGQCXFSSHNL-UHFFFAOYSA-N 2-amino-2-phenylethanol Chemical compound OCC(N)C1=CC=CC=C1 IJXJGQCXFSSHNL-UHFFFAOYSA-N 0.000 abstract 1
- ZQQFSKYVOMMSPD-UHFFFAOYSA-N 2-methylsulfanyl-4,5-dihydro-1,3-thiazole;hydroiodide Chemical compound I.CSC1=NCCS1 ZQQFSKYVOMMSPD-UHFFFAOYSA-N 0.000 abstract 1
- PRGOLSFIIJUXRN-UHFFFAOYSA-N I.OCCC1SCC(N1)=N Chemical compound I.OCCC1SCC(N1)=N PRGOLSFIIJUXRN-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- DDBREPKUVSBGFI-UHFFFAOYSA-N phenobarbital Chemical compound C=1C=CC=CC=1C1(CC)C(=O)NC(=O)NC1=O DDBREPKUVSBGFI-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000006798 ring closing metathesis reaction Methods 0.000 abstract 1
- 125000004953 trihalomethyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUCI000923 HU162754B (enrdf_load_stackoverflow) | 1969-10-01 | 1969-10-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1313219A true GB1313219A (en) | 1973-04-11 |
Family
ID=10994369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3483770A Expired GB1313219A (en) | 1969-10-01 | 1970-07-17 | Process for the preparation of compound having a 2,3,5,6-tetrahydro- imidazo 2,1-b thiazole ring system |
Country Status (14)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3359907A (en) * | 1965-06-24 | 1967-12-26 | Gen Electric | Centra-turbine pump |
| DE102006011574A1 (de) * | 2006-03-10 | 2007-10-31 | Grünenthal GmbH | Substituierte Imidazo[2,1-b]thiazol-Verbindungen und ihre Verwendung zur Herstellung von Arzneimitteln |
-
0
- BE BE755204D patent/BE755204A/xx not_active IP Right Cessation
-
1969
- 1969-10-01 HU HUCI000923 patent/HU162754B/hu unknown
-
1970
- 1970-07-07 AT AT612470A patent/AT296978B/de active
- 1970-07-09 DE DE19702065854 patent/DE2065854C3/de not_active Expired
- 1970-07-17 GB GB3483770A patent/GB1313219A/en not_active Expired
- 1970-07-27 SE SE1031070A patent/SE375994B/xx unknown
- 1970-07-28 DK DK391970A patent/DK132706C/da not_active IP Right Cessation
- 1970-07-29 FR FR7028004A patent/FR2065842A5/fr not_active Expired
- 1970-07-30 SU SU1469620A patent/SU474149A3/ru active
- 1970-07-30 YU YU192070A patent/YU34242B/xx unknown
- 1970-09-01 NL NL7012909A patent/NL153546B/xx not_active IP Right Cessation
- 1970-09-17 CH CH1382970A patent/CH542234A/de not_active IP Right Cessation
- 1970-09-29 CS CS659570A patent/CS171334B1/cs unknown
- 1970-10-01 CA CA094542A patent/CA921924A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2065854C3 (de) | 1978-08-24 |
| HU162754B (enrdf_load_stackoverflow) | 1973-04-28 |
| SU474149A3 (ru) | 1975-06-14 |
| FR2065842A5 (enrdf_load_stackoverflow) | 1971-08-06 |
| BE755204A (enrdf_load_stackoverflow) | 1971-02-01 |
| DK132706B (da) | 1976-01-26 |
| NL153546B (nl) | 1977-06-15 |
| DE2065854A1 (de) | 1976-07-08 |
| DE2065854B2 (de) | 1977-12-01 |
| CH542234A (de) | 1973-09-30 |
| CA921924A (en) | 1973-02-27 |
| AT296978B (de) | 1972-03-10 |
| SE375994B (enrdf_load_stackoverflow) | 1975-05-05 |
| DE2034081A1 (de) | 1971-04-08 |
| DE2034081B2 (de) | 1977-05-18 |
| DK132706C (da) | 1976-08-02 |
| CS171334B1 (enrdf_load_stackoverflow) | 1976-10-29 |
| NL7012909A (enrdf_load_stackoverflow) | 1971-04-05 |
| YU192070A (en) | 1978-10-31 |
| YU34242B (en) | 1979-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLE | Entries relating assignments, transmissions, licences in the register of patents | ||
| PE20 | Patent expired after termination of 20 years |