GB1256593A - - Google Patents
Info
- Publication number
- GB1256593A GB1256593A GB1256593DA GB1256593A GB 1256593 A GB1256593 A GB 1256593A GB 1256593D A GB1256593D A GB 1256593DA GB 1256593 A GB1256593 A GB 1256593A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- amino
- alkylamino
- alkoxy
- isopropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000003282 alkyl amino group Chemical group 0.000 abstract 3
- 230000002152 alkylating effect Effects 0.000 abstract 3
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 abstract 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- SSKHXNLRGBGXTO-UHFFFAOYSA-N (2-amino-5-chloro-4-methylphenyl)-phenylmethanol Chemical compound NC1=C(C(C2=CC=CC=C2)O)C=C(C(=C1)C)Cl SSKHXNLRGBGXTO-UHFFFAOYSA-N 0.000 abstract 1
- CTOUNZIAEBIWAW-UHFFFAOYSA-N 3,4-dihydro-1h-quinazolin-2-one Chemical class C1=CC=C2NC(=O)NCC2=C1 CTOUNZIAEBIWAW-UHFFFAOYSA-N 0.000 abstract 1
- XCEYKKJMLOFDSS-UHFFFAOYSA-N 4-chloro-n-methylaniline Chemical compound CNC1=CC=C(Cl)C=C1 XCEYKKJMLOFDSS-UHFFFAOYSA-N 0.000 abstract 1
- PFUUEZRQEPXGQU-UHFFFAOYSA-N [4-methyl-2-(propan-2-ylamino)phenyl]-phenylmethanone Chemical compound CC(C)NC1=CC(C)=CC=C1C(=O)C1=CC=CC=C1 PFUUEZRQEPXGQU-UHFFFAOYSA-N 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/80—Oxygen atoms
- C07D239/82—Oxygen atoms with an aryl radical attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
- G02B27/02—Viewing or reading apparatus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74180768A | 1968-07-01 | 1968-07-01 | |
| US78725468A | 1968-12-26 | 1968-12-26 | |
| US81943569A | 1969-04-25 | 1969-04-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1256593A true GB1256593A (enrdf_load_stackoverflow) | 1971-12-08 |
Family
ID=27419280
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1256593D Expired GB1256593A (enrdf_load_stackoverflow) | 1968-07-01 | 1969-06-13 |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE735439A (enrdf_load_stackoverflow) |
| CH (1) | CH515911A (enrdf_load_stackoverflow) |
| DE (1) | DE1932396A1 (enrdf_load_stackoverflow) |
| ES (6) | ES368949A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2012062A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1256593A (enrdf_load_stackoverflow) |
| NL (1) | NL6909864A (enrdf_load_stackoverflow) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE759671A (fr) * | 1969-12-01 | 1971-06-01 | Sandoz Sa | Derives de la quinazolinone, leur preparation et medicaments contenant ces derives |
| DK129348B (da) * | 1970-07-13 | 1974-09-30 | Sumitomo Chemical Co | Analogifremgangsmåde til fremstilling af 1-substituerede 3,4-dihydro-2(1H)-quinazolinonderivater. |
| AU438472B2 (en) * | 1970-12-23 | 1973-08-09 | Sumitomo Chemical Company, Limited | Quinazolinone derivatives anda process for production thereof |
| IL102764A0 (en) * | 1991-08-16 | 1993-01-31 | Merck & Co Inc | Quinazoline derivatives,and pharmaceutical compositions containing them |
| WO1993004047A1 (en) * | 1991-08-16 | 1993-03-04 | Merck & Co., Inc. | Quinazoline derivatives as inhibitors of hiv reverse transcriptase |
| EP0626373B1 (en) * | 1993-05-26 | 1998-12-23 | Sumitomo Pharmaceuticals Company, Limited | Quinazolinone derivatives |
| EP3102567B1 (en) * | 2014-02-04 | 2019-07-17 | University of Tennessee Research Foundation | Inhibitors of paxillin function and related compositions and methods |
-
1969
- 1969-06-11 CH CH889369A patent/CH515911A/de not_active IP Right Cessation
- 1969-06-13 GB GB1256593D patent/GB1256593A/en not_active Expired
- 1969-06-26 DE DE19691932396 patent/DE1932396A1/de active Pending
- 1969-06-26 NL NL6909864A patent/NL6909864A/xx unknown
- 1969-06-30 FR FR6921995A patent/FR2012062A1/fr not_active Withdrawn
- 1969-06-30 ES ES368949A patent/ES368949A1/es not_active Expired
- 1969-06-30 BE BE735439D patent/BE735439A/xx unknown
-
1971
- 1971-03-01 ES ES388762A patent/ES388762A1/es not_active Expired
- 1971-03-01 ES ES388759A patent/ES388759A1/es not_active Expired
- 1971-03-01 ES ES388760A patent/ES388760A1/es not_active Expired
- 1971-03-01 ES ES388758A patent/ES388758A1/es not_active Expired
- 1971-03-01 ES ES388761A patent/ES388761A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES388758A1 (es) | 1974-03-01 |
| ES388762A1 (es) | 1974-03-01 |
| ES388759A1 (es) | 1974-03-01 |
| ES388761A1 (es) | 1974-03-01 |
| ES368949A1 (es) | 1971-07-16 |
| BE735439A (enrdf_load_stackoverflow) | 1969-12-30 |
| FR2012062A1 (enrdf_load_stackoverflow) | 1970-03-13 |
| ES388760A1 (es) | 1974-03-01 |
| CH515911A (de) | 1971-11-30 |
| DE1932396A1 (de) | 1970-01-08 |
| NL6909864A (enrdf_load_stackoverflow) | 1970-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |