GB1219249A - Pyrimidopyrimidine derivatives - Google Patents
Pyrimidopyrimidine derivativesInfo
- Publication number
- GB1219249A GB1219249A GB38448/69A GB3844869A GB1219249A GB 1219249 A GB1219249 A GB 1219249A GB 38448/69 A GB38448/69 A GB 38448/69A GB 3844869 A GB3844869 A GB 3844869A GB 1219249 A GB1219249 A GB 1219249A
- Authority
- GB
- United Kingdom
- Prior art keywords
- morpholino
- july
- group
- formula
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1,219,249. Pyrimidopyrimidine derivatives. KARL THOMAE G.m.b.H. 31 July, 1969 [31 July, 1968; 1 July, 1969], No. 38448/69. Heading C2C. Compounds of the general formula (R 1 = C 2-3 alkyl or hydroxyalkyl or methoxy (C 2-3 alkyl); R 2 = C 2-3 hydroxyalkyl) are prepared by (a) reducing a compound of the formula and oxidizing the hydrogenated compound obtained, or (b) reacting a compound of the formula (A = group which may be interchanged with -NR 1 R 2 by reaction with an appropriate amine and A 1 , 2 = morpholino, or A = -NR 1 R 2 and A 1 , 2 = morpholino or group which may be interchanged with a morpholino group by reaction with morpholine, provided that at least one of A 1 , 2 is not morpholino) with R 1 R 2 NH and/or morpholine. The above compounds act on the heart and circulation and inhibit thrombocyte aggregation. They may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19681795032 DE1795032A1 (en) | 1968-07-31 | 1968-07-31 | 2,6-Dimorpholino-8-diaethanolamino-pyrimido [5,4-d] pyrimidine |
| DE19691933426 DE1933426A1 (en) | 1969-07-01 | 1969-07-01 | 2,6-Dimorpholino-8-alkanolamino-pyrimido- [5,4-d] pyrimidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1219249A true GB1219249A (en) | 1971-01-13 |
Family
ID=25756098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB38448/69A Expired GB1219249A (en) | 1968-07-31 | 1969-07-31 | Pyrimidopyrimidine derivatives |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS4819320B1 (en) |
| AT (2) | AT297716B (en) |
| BE (1) | BE736918A (en) |
| BG (2) | BG17320A3 (en) |
| CH (2) | CH516589A (en) |
| DK (1) | DK125248B (en) |
| ES (2) | ES370066A1 (en) |
| FR (1) | FR2014090B1 (en) |
| GB (1) | GB1219249A (en) |
| IL (1) | IL32738A (en) |
| NL (1) | NL6911659A (en) |
| PL (1) | PL80260B1 (en) |
| RO (2) | RO57682A (en) |
| SE (1) | SE351850B (en) |
| SU (1) | SU425397A3 (en) |
-
1969
- 1969-07-22 BG BG12722A patent/BG17320A3/xx unknown
- 1969-07-22 BG BG12723A patent/BG17321A3/xx unknown
- 1969-07-23 SU SU1352298A patent/SU425397A3/en active
- 1969-07-24 DK DK402769AA patent/DK125248B/en unknown
- 1969-07-28 SE SE10591/69A patent/SE351850B/xx unknown
- 1969-07-29 RO RO196971083A patent/RO57682A/ro unknown
- 1969-07-29 RO RO196960654A patent/RO56101A/ro unknown
- 1969-07-30 IL IL32738A patent/IL32738A/en unknown
- 1969-07-30 ES ES370066A patent/ES370066A1/en not_active Expired
- 1969-07-30 AT AT388471A patent/AT297716B/en not_active IP Right Cessation
- 1969-07-30 PL PL1969135131A patent/PL80260B1/pl unknown
- 1969-07-30 JP JP44059720A patent/JPS4819320B1/ja active Pending
- 1969-07-30 AT AT735469A patent/AT296993B/en not_active IP Right Cessation
- 1969-07-30 ES ES370065A patent/ES370065A1/en not_active Expired
- 1969-07-30 NL NL6911659A patent/NL6911659A/xx unknown
- 1969-07-31 GB GB38448/69A patent/GB1219249A/en not_active Expired
- 1969-07-31 FR FR696926307A patent/FR2014090B1/fr not_active Expired
- 1969-07-31 CH CH1169769A patent/CH516589A/en not_active IP Right Cessation
- 1969-07-31 CH CH1409471A patent/CH529164A/en not_active IP Right Cessation
- 1969-07-31 BE BE736918D patent/BE736918A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4819320B1 (en) | 1973-06-12 |
| AT297716B (en) | 1972-04-10 |
| ES370066A1 (en) | 1971-04-01 |
| ES370065A1 (en) | 1971-04-01 |
| RO57682A (en) | 1975-01-15 |
| CH516589A (en) | 1971-12-15 |
| SU425397A3 (en) | 1974-04-25 |
| CH529164A (en) | 1972-10-15 |
| FR2014090A1 (en) | 1970-04-10 |
| IL32738A0 (en) | 1969-11-12 |
| BG17320A3 (en) | 1973-07-25 |
| AT296993B (en) | 1972-03-10 |
| IL32738A (en) | 1973-07-30 |
| SE351850B (en) | 1972-12-11 |
| RO56101A (en) | 1974-03-01 |
| BE736918A (en) | 1970-02-02 |
| PL80260B1 (en) | 1975-08-30 |
| DK125248B (en) | 1973-01-22 |
| NL6911659A (en) | 1970-02-03 |
| BG17321A3 (en) | 1973-07-25 |
| FR2014090B1 (en) | 1973-07-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1147379A (en) | 4-alkyl-dialkoxy-ª‡-methylphenethylamines and pharmacologically acceptable salts | |
| GB1475314A (en) | Phenyl-propylamine derivatives | |
| GB1219249A (en) | Pyrimidopyrimidine derivatives | |
| GB1280288A (en) | Pyrimidopyrimidines | |
| GB1507414A (en) | Hydantoin derivatives | |
| SE7412147L (en) | ||
| GB1387803A (en) | Watersoluble salts of polyhydroxyphenylchromanones | |
| GB1132397A (en) | Improvements in or relating to fluorene derivatives and the manufacture thereof | |
| GB1244961A (en) | Thiazole derivatives | |
| GB1175617A (en) | Substituted Pteridine Derivatives | |
| GB1431259A (en) | 1-substituted-6-phenyl-4h-s-triazolo- 4,3-a- 1,4- benzodiazepines | |
| GB1371757A (en) | Substituted aminoquinolizinium bromides their preparation and compositions thereof | |
| GB1327930A (en) | 1,4-benzodiazepine derivatives | |
| GB1394184A (en) | 4,5-dihydropyridazine-3 2h- ones | |
| GB1391081A (en) | Optically active benzodiazepines | |
| GB1313056A (en) | Pyrimidopyrimidines | |
| GB1432731A (en) | Pyrimidopyrimidines | |
| GB1470748A (en) | 6-2-pyridyl-4h-s-triazolo-4,3-a-1,4-benzodiazepines | |
| GB1442222A (en) | Benzodiazepine derivatives | |
| GB1189782A (en) | New Propanolol Derivatives, Process for their Preparation and Therapeutical Composition Containing Same | |
| GB1374475A (en) | Benzodiazepine derivatives | |
| GB1171827A (en) | Improvements in or relating to Substituted Propanols and the Manufacture thereof | |
| GB1235957A (en) | Alkaloid derivative | |
| GB1276942A (en) | Derivatives of chloramphenicol and thiamphenicol | |
| GB1329130A (en) | Isoindolo 1,2-b benzothiazol-11 -4bh- one 5-oxides |