ES370066A1 - Pyrimidopyrimidine derivatives - Google Patents
Pyrimidopyrimidine derivativesInfo
- Publication number
- ES370066A1 ES370066A1 ES370066A ES370066A ES370066A1 ES 370066 A1 ES370066 A1 ES 370066A1 ES 370066 A ES370066 A ES 370066A ES 370066 A ES370066 A ES 370066A ES 370066 A1 ES370066 A1 ES 370066A1
- Authority
- ES
- Spain
- Prior art keywords
- morpholino
- group
- formula
- compound
- interchanged
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Compounds of the general formula (R 1 = C 2-3 alkyl or hydroxyalkyl or methoxy (C 2-3 alkyl) R 2 = C 2-3 hydroxyalkyl) are prepared by (a) reducing a compound of the formula and oxidizing the hydrogenated compound obtained, or (b) reacting a compound of the formula (A = group which may be interchanged with -NR 1 R 2 by reaction with an appropriate amine and A 1 , 2 = morpholino, or A = -NR 1 R 2 and A 1 , 2 = morpholino or group which may be interchanged with a morpholino group by reaction with morpholine, provided that at least one of A 1 , 2 is not morpholino) with R 1 R 2 NH and/or morpholine. The above compounds act on the heart and circulation and inhibit thrombocyte aggregation. They may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19681795032 DE1795032A1 (en) | 1968-07-31 | 1968-07-31 | 2,6-Dimorpholino-8-diaethanolamino-pyrimido [5,4-d] pyrimidine |
| DE19691933426 DE1933426A1 (en) | 1969-07-01 | 1969-07-01 | 2,6-Dimorpholino-8-alkanolamino-pyrimido- [5,4-d] pyrimidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES370066A1 true ES370066A1 (en) | 1971-04-01 |
Family
ID=25756098
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES370066A Expired ES370066A1 (en) | 1968-07-31 | 1969-07-30 | Pyrimidopyrimidine derivatives |
| ES370065A Expired ES370065A1 (en) | 1968-07-31 | 1969-07-30 | Pyrimidopyrimidine derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES370065A Expired ES370065A1 (en) | 1968-07-31 | 1969-07-30 | Pyrimidopyrimidine derivatives |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS4819320B1 (en) |
| AT (2) | AT297716B (en) |
| BE (1) | BE736918A (en) |
| BG (2) | BG17321A3 (en) |
| CH (2) | CH516589A (en) |
| DK (1) | DK125248B (en) |
| ES (2) | ES370066A1 (en) |
| FR (1) | FR2014090B1 (en) |
| GB (1) | GB1219249A (en) |
| IL (1) | IL32738A (en) |
| NL (1) | NL6911659A (en) |
| PL (1) | PL80260B1 (en) |
| RO (2) | RO57682A (en) |
| SE (1) | SE351850B (en) |
| SU (1) | SU425397A3 (en) |
-
1969
- 1969-07-22 BG BG012723A patent/BG17321A3/en unknown
- 1969-07-22 BG BG012722A patent/BG17320A3/en unknown
- 1969-07-23 SU SU1352298A patent/SU425397A3/en active
- 1969-07-24 DK DK402769AA patent/DK125248B/en unknown
- 1969-07-28 SE SE10591/69A patent/SE351850B/xx unknown
- 1969-07-29 RO RO196971083A patent/RO57682A/ro unknown
- 1969-07-29 RO RO196960654A patent/RO56101A/ro unknown
- 1969-07-30 ES ES370066A patent/ES370066A1/en not_active Expired
- 1969-07-30 AT AT388471A patent/AT297716B/en not_active IP Right Cessation
- 1969-07-30 AT AT735469A patent/AT296993B/en not_active IP Right Cessation
- 1969-07-30 ES ES370065A patent/ES370065A1/en not_active Expired
- 1969-07-30 JP JP44059720A patent/JPS4819320B1/ja active Pending
- 1969-07-30 PL PL1969135131A patent/PL80260B1/pl unknown
- 1969-07-30 NL NL6911659A patent/NL6911659A/xx unknown
- 1969-07-30 IL IL32738A patent/IL32738A/en unknown
- 1969-07-31 FR FR696926307A patent/FR2014090B1/fr not_active Expired
- 1969-07-31 CH CH1169769A patent/CH516589A/en not_active IP Right Cessation
- 1969-07-31 BE BE736918D patent/BE736918A/xx unknown
- 1969-07-31 CH CH1409471A patent/CH529164A/en not_active IP Right Cessation
- 1969-07-31 GB GB38448/69A patent/GB1219249A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT296993B (en) | 1972-03-10 |
| BE736918A (en) | 1970-02-02 |
| IL32738A (en) | 1973-07-30 |
| JPS4819320B1 (en) | 1973-06-12 |
| ES370065A1 (en) | 1971-04-01 |
| PL80260B1 (en) | 1975-08-30 |
| RO56101A (en) | 1974-03-01 |
| DK125248B (en) | 1973-01-22 |
| BG17321A3 (en) | 1973-07-25 |
| AT297716B (en) | 1972-04-10 |
| FR2014090A1 (en) | 1970-04-10 |
| CH529164A (en) | 1972-10-15 |
| CH516589A (en) | 1971-12-15 |
| SE351850B (en) | 1972-12-11 |
| IL32738A0 (en) | 1969-11-12 |
| FR2014090B1 (en) | 1973-07-13 |
| BG17320A3 (en) | 1973-07-25 |
| RO57682A (en) | 1975-01-15 |
| NL6911659A (en) | 1970-02-03 |
| SU425397A3 (en) | 1974-04-25 |
| GB1219249A (en) | 1971-01-13 |
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