GB1211722A - Amine salts of an aromatic phosphoric ester - Google Patents
Amine salts of an aromatic phosphoric esterInfo
- Publication number
- GB1211722A GB1211722A GB35174/69A GB3517469A GB1211722A GB 1211722 A GB1211722 A GB 1211722A GB 35174/69 A GB35174/69 A GB 35174/69A GB 3517469 A GB3517469 A GB 3517469A GB 1211722 A GB1211722 A GB 1211722A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amine
- salts
- amine salts
- nov
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
- C12Q2334/10—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases p-Nitrophenol derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
1,211,722. Amine salts of p-nitrophenyl phosphoric acid. SMITH KLINE & FRENCH LABORATORIES. 1 Nov., 1967 [14 Nov., 1966], No. 35174/69. Divided out of 1,211,721. Heading C2C. The invention comprises amine salts of the general formula wherein R is an amine molecule other than that of 2 - amino - 2 - methyl - 1 - propanol or 2- amino - 2 - methyl - 1,3 - propanediol and n is 1 or 2. They may be obtained by reacting an appropriate amine with p-nitrophenyl phosphoric acid, the amine salt being suitably isolated by precipitation which may be effected by concentration or by the addition of an organic solvent. Examples are given for the production of the di-(cyclohexylammonium) and dimorpholinium salts and the tris-(hydroxymethyl) aminomethane-, methylamine-, ethylamine-, dimethylamine-, trimethylamine-, monobenzylamine-, furfurylamine-, aniline-, and diethanolamine-mono salts. The products are useful in reagent mixtures for detecting and measuring phosphatases in biological liquids such as serum.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59374066A | 1966-11-14 | 1966-11-14 | |
US62743067A | 1967-03-31 | 1967-03-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1211722A true GB1211722A (en) | 1970-11-11 |
Family
ID=27081784
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB35174/69A Expired GB1211722A (en) | 1966-11-14 | 1967-11-01 | Amine salts of an aromatic phosphoric ester |
GB49698/67A Expired GB1211721A (en) | 1966-11-14 | 1967-11-01 | Laboratory reagent for assay of acid or alkaline phosphatase |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB49698/67A Expired GB1211721A (en) | 1966-11-14 | 1967-11-01 | Laboratory reagent for assay of acid or alkaline phosphatase |
Country Status (9)
Country | Link |
---|---|
US (1) | US3425912A (en) |
CA (1) | CA930655A (en) |
CH (1) | CH497702A (en) |
DE (1) | DE1673047C2 (en) |
DK (1) | DK140267B (en) |
GB (2) | GB1211722A (en) |
IL (1) | IL28842A (en) |
NL (1) | NL6715288A (en) |
SE (2) | SE336687B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2415300A1 (en) * | 1978-01-20 | 1979-08-17 | Sclavo Inst Sieroterapeut | COMPOSITION FOR THE ANALYSIS OF ALKALINE PHOSPHATASE AND METHOD FOR ITS IMPLEMENTATION |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3791929A (en) * | 1968-09-08 | 1974-02-12 | Searle & Co | Phosphatase assay using lyophilized aryl phosphate monesters |
US3723579A (en) * | 1969-09-08 | 1973-03-27 | Searle & Co | Lyophilized aryl phosphate monoesters and process therefor |
US3926735A (en) * | 1971-10-20 | 1975-12-16 | Mallinckrodt Inc | Alkaline phosphatase assay |
US3896008A (en) * | 1971-10-28 | 1975-07-22 | Owens Illinois Inc | Electrochemical potentiometric method for selectively determining alkaline phosphatase content in aqueous fluids |
IT1065125B (en) * | 1975-08-20 | 1985-02-25 | Boehringer Mannheim Gmbh | PROCESS TO KEEP THE ACTIVITY OF ALKALINE PHOSPHATASE AND CONTROL SERUM CONTAINING SUCH PHOSPHATASE CONSTANT |
ZA756003B (en) * | 1975-09-22 | 1977-04-27 | Chembro Holdings Pty Ltd | Measurement of alkaline phophatase levels in body fluids |
CH625833A5 (en) * | 1975-12-24 | 1981-10-15 | Hoffmann La Roche | Method for the determination of acid phosphatase |
US4206280A (en) * | 1975-12-24 | 1980-06-03 | Hoffmann-La Roche Inc. | Determination of acid phosphatase |
JPS5377015A (en) * | 1976-12-16 | 1978-07-08 | Asahi Glass Co Ltd | Preparation of fluorine-containing phosphoric acid ester |
US4132598A (en) * | 1977-06-03 | 1979-01-02 | Modrovich Ivan Endre | Stabilized liquid phosphate containing diagnostic compositions and method of preparing same |
US4472499A (en) * | 1982-01-22 | 1984-09-18 | American Hoechst Corporation | Reagents for the determination of enzymes |
US4555484A (en) * | 1983-07-25 | 1985-11-26 | Eastman Kodak Company | Analytical element and method for alkaline phosphatase assay |
CN102297962B (en) * | 2011-05-23 | 2014-01-08 | 董理 | Kit for detecting alkaline phosphatase |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2359052A (en) * | 1940-07-01 | 1944-09-26 | Scharer Harry | Method for detecting enzyme activity |
US3002893A (en) * | 1958-11-13 | 1961-10-03 | Warner Lambert Pharmaceutical | Method for the determination of serum acid phosphatase and diagnostic preparation therefor |
US3069330A (en) * | 1960-08-30 | 1962-12-18 | Warner Lambert Pharmaceutical | Method of determining glutamic-oxal-acetic transaminase and composition therefor |
-
1966
- 1966-11-14 US US593740A patent/US3425912A/en not_active Expired - Lifetime
-
1967
- 1967-10-29 IL IL28842A patent/IL28842A/en unknown
- 1967-11-01 GB GB35174/69A patent/GB1211722A/en not_active Expired
- 1967-11-01 GB GB49698/67A patent/GB1211721A/en not_active Expired
- 1967-11-07 DK DK554067AA patent/DK140267B/en not_active IP Right Cessation
- 1967-11-10 SE SE15439/67A patent/SE336687B/xx unknown
- 1967-11-10 NL NL6715288A patent/NL6715288A/xx unknown
- 1967-11-10 SE SE7006732A patent/SE375384B/xx unknown
- 1967-11-13 CA CA004851A patent/CA930655A/en not_active Expired
- 1967-11-13 DE DE1673047A patent/DE1673047C2/en not_active Expired
- 1967-11-14 CH CH1587567A patent/CH497702A/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2415300A1 (en) * | 1978-01-20 | 1979-08-17 | Sclavo Inst Sieroterapeut | COMPOSITION FOR THE ANALYSIS OF ALKALINE PHOSPHATASE AND METHOD FOR ITS IMPLEMENTATION |
Also Published As
Publication number | Publication date |
---|---|
SE375384B (en) | 1975-04-14 |
DK140267B (en) | 1979-07-16 |
SU444376A3 (en) | 1974-09-25 |
DE1673047B1 (en) | 1972-06-08 |
CA930655A (en) | 1973-07-24 |
DE1673047C2 (en) | 1973-01-04 |
US3425912A (en) | 1969-02-04 |
CH497702A (en) | 1970-10-15 |
NL6715288A (en) | 1968-05-15 |
DK140267C (en) | 1979-12-10 |
GB1211721A (en) | 1970-11-11 |
SE336687B (en) | 1971-07-12 |
IL28842A (en) | 1972-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PE20 | Patent expired after termination of 20 years |