GB1224017A - Process for the preparation of 6-aminopenicillanic acid - Google Patents

Process for the preparation of 6-aminopenicillanic acid

Info

Publication number
GB1224017A
GB1224017A GB44655/68A GB4465568A GB1224017A GB 1224017 A GB1224017 A GB 1224017A GB 44655/68 A GB44655/68 A GB 44655/68A GB 4465568 A GB4465568 A GB 4465568A GB 1224017 A GB1224017 A GB 1224017A
Authority
GB
United Kingdom
Prior art keywords
aminopenicillanic acid
preparation
acid
reacted
alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB44655/68A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Delft BV
Original Assignee
Koninklijke Nederlandsche Gist en Spiritusfabriek BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Nederlandsche Gist en Spiritusfabriek BV filed Critical Koninklijke Nederlandsche Gist en Spiritusfabriek BV
Publication of GB1224017A publication Critical patent/GB1224017A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Abstract

1,224,017. 6 - Aminopenicillanic acid. KONINKLIJKE NEDERLANDSCHE GISTEN SPIRITUSFABRIEK N.V. 19 Sept., 1968 [11 Oct., 1967], No. 44655/68. Addition to 1,189,022. Heading C2A. A process for the preparation of 6-aminopenicillanic acid or a salt thereof as claimed in claim 2 of Specification 1,189,022, in which the silyl ester of the 6-acylaminopenicillanic acid is reacted with a substance capable of forming an imino halide on the 6-amido nitrogen atom and in which the imino halide is reacted with an alcohol to form the imino ether at a temperature not exceeding - 20‹ C. Preferably the reaction with the alcohol is carried out at temperatures of - 40‹ to - 60‹ C.
GB44655/68A 1967-10-11 1968-09-19 Process for the preparation of 6-aminopenicillanic acid Expired GB1224017A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL676713809A NL145861B (en) 1967-10-11 1967-10-11 IMPROVEMENT OF THE METHOD FOR THE CHEMICAL PREPARATION OF 6-AMINOPENICILLAN ACID OR SALTS THEREOF.

Publications (1)

Publication Number Publication Date
GB1224017A true GB1224017A (en) 1971-03-03

Family

ID=19801429

Family Applications (1)

Application Number Title Priority Date Filing Date
GB44655/68A Expired GB1224017A (en) 1967-10-11 1968-09-19 Process for the preparation of 6-aminopenicillanic acid

Country Status (17)

Country Link
JP (1) JPS516152B1 (en)
BE (1) BE722052A (en)
BR (1) BR6803037D0 (en)
CH (1) CH546257A (en)
CS (1) CS159750B2 (en)
DK (1) DK130347B (en)
ES (1) ES358992A2 (en)
FI (1) FI50423C (en)
FR (1) FR95946E (en)
GB (1) GB1224017A (en)
IE (1) IE32415B1 (en)
IL (1) IL30758A0 (en)
IT (1) IT1064102B (en)
NL (1) NL145861B (en)
NO (1) NO136097C (en)
SE (1) SE356301B (en)
YU (1) YU33005B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK155604B (en) * 1979-12-10 1989-04-24 Gist Brocades Nv METHOD OF PREPARING 6-AMINOPENICILLANIC ACID-1,1-DIOXIDE AND ITS NON-TOXIC PHARMACEUTICAL ACCEPTABLE SALTS

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1388265A (en) * 1971-03-12 1975-03-26 Glaxo Lab Ltd Preparation of antibiotic compounds
JPS5976997U (en) * 1982-11-17 1984-05-24 中濃窯業株式会社 Baking jig
JPS61145299U (en) * 1985-02-28 1986-09-08
JPS61159792U (en) * 1985-03-22 1986-10-03

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK155604B (en) * 1979-12-10 1989-04-24 Gist Brocades Nv METHOD OF PREPARING 6-AMINOPENICILLANIC ACID-1,1-DIOXIDE AND ITS NON-TOXIC PHARMACEUTICAL ACCEPTABLE SALTS

Also Published As

Publication number Publication date
DE1795436A1 (en) 1973-01-04
CH546257A (en) 1974-02-28
NO136097C (en) 1977-07-20
IE32415L (en) 1969-04-11
FI50423C (en) 1976-03-10
FR95946E (en) 1972-03-10
BR6803037D0 (en) 1973-02-22
CS159750B2 (en) 1975-01-31
JPS516152B1 (en) 1976-02-25
YU232368A (en) 1975-08-31
YU33005B (en) 1976-03-31
BE722052A (en) 1969-04-09
FI50423B (en) 1975-12-01
DE1795436B2 (en) 1975-06-26
NL6713809A (en) 1969-04-15
NL145861B (en) 1975-05-15
DK130347B (en) 1975-02-10
NO136097B (en) 1977-04-12
SE356301B (en) 1973-05-21
IL30758A0 (en) 1968-11-27
ES358992A2 (en) 1970-05-16
IE32415B1 (en) 1973-07-25
DK130347C (en) 1975-07-07
IT1064102B (en) 1985-02-18

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