GB1205995A - Novel benzodiazepine derivatives and a process for the manufacture thereof - Google Patents

Novel benzodiazepine derivatives and a process for the manufacture thereof

Info

Publication number
GB1205995A
GB1205995A GB31473/68A GB3147368A GB1205995A GB 1205995 A GB1205995 A GB 1205995A GB 31473/68 A GB31473/68 A GB 31473/68A GB 3147368 A GB3147368 A GB 3147368A GB 1205995 A GB1205995 A GB 1205995A
Authority
GB
United Kingdom
Prior art keywords
formula
compound
absent
alkyl
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB31473/68A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1205995A publication Critical patent/GB1205995A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB31473/68A 1967-07-03 1968-07-02 Novel benzodiazepine derivatives and a process for the manufacture thereof Expired GB1205995A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65065167A 1967-07-03 1967-07-03
US65065267A 1967-07-03 1967-07-03

Publications (1)

Publication Number Publication Date
GB1205995A true GB1205995A (en) 1970-09-23

Family

ID=27095915

Family Applications (2)

Application Number Title Priority Date Filing Date
GB31473/68A Expired GB1205995A (en) 1967-07-03 1968-07-02 Novel benzodiazepine derivatives and a process for the manufacture thereof
GB44589/69A Expired GB1205996A (en) 1967-07-03 1968-07-02 Benzophenone derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB44589/69A Expired GB1205996A (en) 1967-07-03 1968-07-02 Benzophenone derivatives

Country Status (11)

Country Link
US (1) US3523939A (https=)
BE (1) BE717478A (https=)
CA (1) CA952106A (https=)
CH (3) CH526558A (https=)
DE (1) DE1770778A1 (https=)
FR (2) FR8488M (https=)
GB (2) GB1205995A (https=)
IE (1) IE32217B1 (https=)
IL (2) IL38208A (https=)
NL (1) NL6809403A (https=)
SE (1) SE358167B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4837280B1 (https=) * 1969-03-08 1973-11-09
US3723414A (en) * 1970-02-13 1973-03-27 Schering Corp 1-polyfluoroalkyl benzodiazepines
AT333284B (de) * 1971-12-09 1976-11-10 Degussa Verfahren zur herstellung von neuen 6-aza-3h-1,4-benzodiazepinen, deren optischen isomeren und deren salzen
US4089953A (en) * 1973-06-20 1978-05-16 Ddsa Pharmaceuticals 1,5-Benzodiazocines
US4056525A (en) * 1975-06-02 1977-11-01 American Home Products Corporation 2,3-dialkoxy-3h-1,4-benzodiazepines
US9096546B2 (en) * 2007-05-10 2015-08-04 Albany Molecular Research, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
AR084070A1 (es) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc Inhibidores del bromodominio y usos de los mismos
US9249161B2 (en) 2010-12-02 2016-02-02 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
WO2012151512A2 (en) 2011-05-04 2012-11-08 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
EP2721031B1 (en) 2011-06-17 2016-01-20 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
TWI602820B (zh) 2012-06-06 2017-10-21 星宿藥物公司 溴域抑制劑及其用途
EP2864336B1 (en) 2012-06-06 2016-11-23 Constellation Pharmaceuticals, Inc. Benzo[b]isoxazoloazepine bromodomain inhibitors and uses thereof
CA2952830C (en) 2014-06-20 2022-11-01 Constellation Pharmaceuticals, Inc. Crystalline forms of 2-((4s)-6-(4-chlorophenyl)-1-methyl-4h-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2893992A (en) * 1959-07-07 I ii i i
US3109843A (en) * 1963-11-05 Process for preparing
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones
GB1051795A (https=) * 1964-02-11

Also Published As

Publication number Publication date
US3523939A (en) 1970-08-11
CH526558A (de) 1972-08-15
SE358167B (https=) 1973-07-23
CA952106A (en) 1974-07-30
IL30282A0 (en) 1968-09-26
FR1586872A (https=) 1970-03-06
DE1770778A1 (de) 1972-02-17
CH512475A (de) 1971-09-15
IL38208A (en) 1973-04-30
NL6809403A (https=) 1969-01-07
GB1205996A (en) 1970-09-23
FR8488M (https=) 1973-07-27
CH524621A (de) 1972-06-30
IE32217L (en) 1969-01-03
BE717478A (https=) 1969-01-02
IE32217B1 (en) 1973-05-16
IL30282A (en) 1972-11-28

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee