GB1237764A - New diarylethylamines, process for their production and compositions containing same - Google Patents

New diarylethylamines, process for their production and compositions containing same

Info

Publication number
GB1237764A
GB1237764A GB3415068A GB3415068A GB1237764A GB 1237764 A GB1237764 A GB 1237764A GB 3415068 A GB3415068 A GB 3415068A GB 3415068 A GB3415068 A GB 3415068A GB 1237764 A GB1237764 A GB 1237764A
Authority
GB
United Kingdom
Prior art keywords
formula
alkoxy
compounds
compound
diarylethylamines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3415068A
Inventor
Ralph David Tanz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to NL6809840A priority Critical patent/NL6809840A/xx
Application filed by JR Geigy AG filed Critical JR Geigy AG
Priority to DE19681768970 priority patent/DE1768970A1/en
Priority to BE718240D priority patent/BE718240A/xx
Priority to GB3415068A priority patent/GB1237764A/en
Publication of GB1237764A publication Critical patent/GB1237764A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/39—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
    • C07C205/42—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton

Abstract

1,237,764. Diarylethylamine derivatives. J. R. GEIGY A.G. 18 July, 1968, No. 34150/68. Heading C2C. Compounds of the general formula (W = H, Cl, F, Br, OH; X, Y = H, Cl, F, OH, C 1-3 alkoxy; Z = H, OH, CH 2 OH; R 1 = H, Me, Et; R 2 , 3 , 4 , 6 = H, Me; R 5 = H, Me, Ph, hydroxyphenyl) and their acid addition salts are prepared by (a) reducing a compound of the formula (Z<SP>1</SP> = H, OH, COOH, COOAlkyl), (b)-in the case of compounds of the formula (W<SP>11</SP> = H, OH; X<SP>11</SP>, Y<SP>11</SP> = H, OH, C 1-3 alkoxy; R<SP>1</SP> 3 = Me; R 4 , 5 = H, Me)-reducing a compound of the formula or (c)-in the ease of compounds of the formula (X<SP>11</SP> = H, OH, C 1-3 alkoxy)-condensing #- naphthol with a compound of the formula (X<SP>111</SP> = H, OH, C 1-3 alkoxy, acetoxy, propionoxy), optionally followed in each case by salt formation. The above compounds are useful in the treatment of primary arrhythmias and also have hypotensive and local anaesthetic activity. They may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
GB3415068A 1968-07-11 1968-07-18 New diarylethylamines, process for their production and compositions containing same Expired GB1237764A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
NL6809840A NL6809840A (en) 1968-07-11 1968-07-11
DE19681768970 DE1768970A1 (en) 1968-07-11 1968-07-18 New Diarylaethylamines and Processes for Their Preparation
BE718240D BE718240A (en) 1968-07-11 1968-07-18
GB3415068A GB1237764A (en) 1968-07-11 1968-07-18 New diarylethylamines, process for their production and compositions containing same

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
NL6809840A NL6809840A (en) 1968-07-11 1968-07-11
DE19681768970 DE1768970A1 (en) 1968-07-11 1968-07-18 New Diarylaethylamines and Processes for Their Preparation
GB3415068A GB1237764A (en) 1968-07-11 1968-07-18 New diarylethylamines, process for their production and compositions containing same
BE718240 1968-07-18

Publications (1)

Publication Number Publication Date
GB1237764A true GB1237764A (en) 1971-06-30

Family

ID=27424921

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3415068A Expired GB1237764A (en) 1968-07-11 1968-07-18 New diarylethylamines, process for their production and compositions containing same

Country Status (4)

Country Link
BE (1) BE718240A (en)
DE (1) DE1768970A1 (en)
GB (1) GB1237764A (en)
NL (1) NL6809840A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2267088A (en) * 1992-05-22 1993-11-24 Ciba Geigy Ag Benzofuran-2-ones as stabilisers
GB2267491A (en) * 1992-05-22 1993-12-08 Ciba Geigy Ag Benzofuran-2-one stabilisers

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2267088A (en) * 1992-05-22 1993-11-24 Ciba Geigy Ag Benzofuran-2-ones as stabilisers
GB2267491A (en) * 1992-05-22 1993-12-08 Ciba Geigy Ag Benzofuran-2-one stabilisers
US5367008A (en) * 1992-05-22 1994-11-22 Ciba-Geigy Corporation 3-(alkoxyphenyl)benzofuran-2-ones as stabilisers
US5369159A (en) * 1992-05-22 1994-11-29 Ciba-Geigy Corporation 3-(acyloxyphenyl)benzofuran-2-one stabilizers
GB2267491B (en) * 1992-05-22 1996-01-10 Ciba Geigy Ag 3-(Acyloxyphenyl) benzofuran-2-one stabilisers
GB2267088B (en) * 1992-05-22 1996-01-24 Ciba Geigy Ag 3-(Alkoxyphenyl)benzofuran-2-ones as stabilisers
US5488117A (en) * 1992-05-22 1996-01-30 Ciba-Geigy Corporation 3-(acyloxyphenyl)benzofuran-2-one stabilisers

Also Published As

Publication number Publication date
BE718240A (en) 1969-01-20
DE1768970A1 (en) 1972-01-05
NL6809840A (en) 1970-01-13

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