GB1321938A - Benzodiazepine derivatives and a process for the manjfacture thereof - Google Patents
Benzodiazepine derivatives and a process for the manjfacture thereofInfo
- Publication number
- GB1321938A GB1321938A GB5998071A GB5998071A GB1321938A GB 1321938 A GB1321938 A GB 1321938A GB 5998071 A GB5998071 A GB 5998071A GB 5998071 A GB5998071 A GB 5998071A GB 1321938 A GB1321938 A GB 1321938A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- dec
- manjfacture
- benzodiazepine derivatives
- dihydrobenzodiazepines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1321938 Benzodiazepines F HOFFMANNLA ROCHE & CO AG 23 Dec 1971 [23 Dec 1970] 59980/71 Heading C2C Compounds of the general formula (R, R<SP>1</SP>, R<SP>2</SP> = H, C 1-7 alkyl; R<SP>3</SP>=H, halogen; R<SP>4,5</SP>=H or R<SP>4+5</SP>= additional bond; R<SP>6,7</SP> alone or together = moiety removable by acid hydrolysis), 4-oxides of the dihydrobenzodiazepines and acid addition salts of the basic compounds are prepared by cyclizing a compound of the formula optionally followed by one or more of the steps reduction, oxidation, alkylation, salt formation. The above compounds are muscle relaxants, sedatives and anticonvulsants, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10118370A | 1970-12-23 | 1970-12-23 | |
US10111770A | 1970-12-23 | 1970-12-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1321938A true GB1321938A (en) | 1973-07-04 |
Family
ID=26797912
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5998071A Expired GB1321938A (en) | 1970-12-23 | 1971-12-23 | Benzodiazepine derivatives and a process for the manjfacture thereof |
Country Status (21)
Country | Link |
---|---|
JP (1) | JPS5610310B1 (en) |
AR (1) | AR193632A1 (en) |
AT (2) | AT322556B (en) |
AU (1) | AU458983B2 (en) |
BE (2) | BE777097A (en) |
BG (1) | BG17804A3 (en) |
BR (1) | BR7108411D0 (en) |
CA (2) | CA935157A (en) |
CH (2) | CH582162A5 (en) |
DD (1) | DD95384A5 (en) |
DE (2) | DE2163522A1 (en) |
ES (1) | ES398222A1 (en) |
FR (2) | FR2154391B1 (en) |
GB (1) | GB1321938A (en) |
HU (1) | HU164249B (en) |
IL (1) | IL38234A0 (en) |
LU (1) | LU64491A1 (en) |
NL (3) | NL7117480A (en) |
PL (1) | PL83080B1 (en) |
RO (1) | RO70586A (en) |
YU (1) | YU35004B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100932093B1 (en) | 2006-09-27 | 2009-12-16 | 주식회사종근당 | Benzophenone Derivatives Useful as Inhibitors of Microtubule Formation |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4833759A (en) * | 1971-09-01 | 1973-05-12 |
-
1971
- 1971-11-26 IL IL38234A patent/IL38234A0/en unknown
- 1971-11-30 CH CH1740171A patent/CH582162A5/xx not_active IP Right Cessation
- 1971-12-03 CH CH1761371A patent/CH565775A5/xx not_active IP Right Cessation
- 1971-12-03 CA CA129226A patent/CA935157A/en not_active Expired
- 1971-12-20 NL NL7117480A patent/NL7117480A/xx not_active Application Discontinuation
- 1971-12-20 BR BR8411/71A patent/BR7108411D0/en unknown
- 1971-12-21 CA CA130,660A patent/CA948629A/en not_active Expired
- 1971-12-21 LU LU64491A patent/LU64491A1/xx unknown
- 1971-12-21 DE DE19712163522 patent/DE2163522A1/en active Pending
- 1971-12-21 DE DE19712163642 patent/DE2163642A1/en active Pending
- 1971-12-21 JP JP10401571A patent/JPS5610310B1/ja active Pending
- 1971-12-21 RO RO7169138A patent/RO70586A/en unknown
- 1971-12-21 AU AU37153/71A patent/AU458983B2/en not_active Expired
- 1971-12-22 BE BE777097A patent/BE777097A/en unknown
- 1971-12-22 AT AT1105071A patent/AT322556B/en not_active IP Right Cessation
- 1971-12-22 BE BE777098A patent/BE777098A/en unknown
- 1971-12-22 AR AR239761A patent/AR193632A1/en active
- 1971-12-22 DD DD159822A patent/DD95384A5/xx unknown
- 1971-12-22 ES ES398222A patent/ES398222A1/en not_active Expired
- 1971-12-22 AT AT847174*1A patent/AT325628B/en not_active IP Right Cessation
- 1971-12-23 YU YU3235/71A patent/YU35004B/en unknown
- 1971-12-23 FR FR7146456A patent/FR2154391B1/fr not_active Expired
- 1971-12-23 GB GB5998071A patent/GB1321938A/en not_active Expired
- 1971-12-23 FR FR7146455A patent/FR2119070A1/en not_active Withdrawn
- 1971-12-23 BG BG19309A patent/BG17804A3/xx unknown
- 1971-12-23 NL NL7117762A patent/NL7117762A/xx unknown
- 1971-12-23 NL NL7117760A patent/NL7117760A/xx unknown
- 1971-12-23 PL PL1971152445A patent/PL83080B1/pl unknown
- 1971-12-23 HU HUHO1442A patent/HU164249B/hu unknown
Also Published As
Publication number | Publication date |
---|---|
YU35004B (en) | 1980-06-30 |
PL83080B1 (en) | 1975-12-31 |
AU458983B2 (en) | 1975-03-13 |
AU3715371A (en) | 1973-06-28 |
FR2154391B1 (en) | 1975-03-14 |
BE777098A (en) | 1972-06-22 |
AT325628B (en) | 1975-10-27 |
BR7108411D0 (en) | 1973-06-14 |
YU323571A (en) | 1979-12-31 |
BG17804A3 (en) | 1973-12-25 |
DE2163642A1 (en) | 1972-07-13 |
CH565775A5 (en) | 1975-08-29 |
CH582162A5 (en) | 1976-11-30 |
DD95384A5 (en) | 1973-02-05 |
DE2163522A1 (en) | 1972-07-13 |
NL7117760A (en) | 1972-06-27 |
FR2119070A1 (en) | 1972-08-04 |
ES398222A1 (en) | 1975-06-01 |
AR193632A1 (en) | 1973-05-11 |
BE777097A (en) | 1972-06-22 |
LU64491A1 (en) | 1973-07-16 |
CA948629A (en) | 1974-06-04 |
NL7117762A (en) | 1972-06-27 |
JPS5610310B1 (en) | 1981-03-06 |
HU164249B (en) | 1974-01-28 |
NL7117480A (en) | 1972-06-27 |
CA935157A (en) | 1973-10-09 |
RO70586A (en) | 1981-07-30 |
IL38234A0 (en) | 1972-01-27 |
FR2154391A1 (en) | 1973-05-11 |
AT322556B (en) | 1975-05-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PLNP | Patent lapsed through nonpayment of renewal fees |