GB1199871A - Improvements in or relating to Sulfur-Containing Bisphenols - Google Patents

Improvements in or relating to Sulfur-Containing Bisphenols

Info

Publication number
GB1199871A
GB1199871A GB20551/68A GB2055168A GB1199871A GB 1199871 A GB1199871 A GB 1199871A GB 20551/68 A GB20551/68 A GB 20551/68A GB 2055168 A GB2055168 A GB 2055168A GB 1199871 A GB1199871 A GB 1199871A
Authority
GB
United Kingdom
Prior art keywords
hydroxyphenylmercapto
bis
butyl
propane
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB20551/68A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consolidation Coal Co
Original Assignee
Consolidation Coal Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consolidation Coal Co filed Critical Consolidation Coal Co
Publication of GB1199871A publication Critical patent/GB1199871A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/36—Sulfur-, selenium-, or tellurium-containing compounds
    • C08K5/37—Thiols
    • C08K5/375—Thiols containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB20551/68A 1967-05-11 1968-05-01 Improvements in or relating to Sulfur-Containing Bisphenols Expired GB1199871A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63765067A 1967-05-11 1967-05-11
US63764967A 1967-05-11 1967-05-11

Publications (1)

Publication Number Publication Date
GB1199871A true GB1199871A (en) 1970-07-22

Family

ID=27092902

Family Applications (1)

Application Number Title Priority Date Filing Date
GB20551/68A Expired GB1199871A (en) 1967-05-11 1968-05-01 Improvements in or relating to Sulfur-Containing Bisphenols

Country Status (3)

Country Link
DE (1) DE1768334C3 (fr)
FR (2) FR8063M (fr)
GB (1) GB1199871A (fr)

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4560799A (en) 1984-02-03 1985-12-24 Ciba-Geigy Corporation Tri- and Tetra-(substituted hydroxyphenylthio) alkane and cycloalkane stabilizers and stabilized compositions
EP0275952A1 (fr) * 1987-01-20 1988-07-27 Merrell Dow Pharmaceuticals Inc. Procédé de la préparation du ditertiobutyl-2,6 mercapto-4 phénol et de l'isopropylidènedithio-4,4'-bis(ditertiobutyl-2,6 phénol)
US4900757A (en) * 1988-12-08 1990-02-13 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic and antiatherosclerotic uses of bix(3,5-di-tertiary-butyl-4-hydroxyphenylthio)methane
US4954528A (en) * 1988-12-08 1990-09-04 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic use of bis(3,5-di-tertiary-butly-4-hydroxyphenylthio)methane
US4959392A (en) * 1989-07-24 1990-09-25 Merrell Dow Pharmaceuticals Inc. Method of treating diabetes mellitus
US4975467A (en) * 1987-03-17 1990-12-04 Merrell Dow Pharmaceuticals Inc. Method of inhibiting interleukin-1 release and alleviating interleukin-1 mediated conditions
US5401883A (en) * 1987-01-20 1995-03-28 Merrell Dow Pharmaceuticals Inc. Process for preparing 2,6-di-tertiarybutyl-4-mercaptophenol and 4,4'-isopropylidenedithio-bis-(2,6-di-tertiarybutylphenol)
US5795876A (en) * 1996-04-30 1998-08-18 Hoechst Marion Rousssel, Inc. Method of inhibiting vascular cell adhesion molecule-1 and treating chronic inflammatory diseases with 2, 6-di-alkyl-4-silyl-phenols
WO1998051662A2 (fr) * 1997-05-14 1998-11-19 Atherogenics, Inc. Composes et methodes d'inhibition de l'expression de vcam-1
US5962435A (en) * 1993-12-10 1999-10-05 Hoechst Marion Roussel, Inc. Method of lowering serum cholesterol levels with 2,6-di-alkyl-4-silyl-phenols
US6114572A (en) * 1996-11-20 2000-09-05 Hoechst Marion Roussel, Inc. Substituted phenols and thiophenols useful as antioxidant agents
US6121463A (en) * 1997-06-24 2000-09-19 Hoechst Marion Roussel, Inc. Alkyl-4-silylheterocyclic phenols and thiophenols useful as antioxidant agents
US6133467A (en) * 1997-06-25 2000-10-17 Hoechst Marion Roussel, Inc. 2,6-di-t-butyl-4-[(dimethyl-4-methoxyphenylsilyl)-methyl-oxy]phenol and 2,6-di-t-butyl-4-[(dimethyl-2-methoxy-phenylsilyl)methyloxy]phenol
US6670398B2 (en) 1997-05-14 2003-12-30 Atherogenics, Inc. Compounds and methods for treating transplant rejection
US6852878B2 (en) 1998-05-14 2005-02-08 Atherogenics, Inc. Thioketals and thioethers for inhibiting the expression of VCAM-1
AU2002300328B2 (en) * 1997-05-14 2006-04-13 Atherogenics, Inc Compounds and methods for the inhibition of the expression of VCAM-1
WO2006063408A1 (fr) * 2004-12-17 2006-06-22 Stocker Ronald O Préparations et méthodes pour le traitement de troubles cardio-vasculaires
EP1695959A1 (fr) * 1997-05-14 2006-08-30 Atherogenics, Inc. Composes et methodes d'inhibition de l'expression de VCAM-1
US7294737B2 (en) 2004-04-20 2007-11-13 Atherogenics, Inc. Process of preparing esters and ethers of probucol and derivatives thereof
AU2006202461B2 (en) * 1997-05-14 2009-12-03 Atherogenics, Inc. Compositions and methods for the inhibition of the expression of VCAM-1
US8252840B2 (en) 2007-03-26 2012-08-28 Salutria Pharmaceuticals Llc Methods of derivatives of probucol for the treatment of type II diabetes

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1421108A (en) * 1973-09-07 1976-01-14 Exxon Research Engineering Co Sulphurised phenols
NZ205559A (en) * 1982-09-23 1987-08-31 Merck Frosst Canada Inc Leukotriene antagonists, pharmaceutical compositions, and intermediates
EP0106565B1 (fr) * 1982-09-30 1986-09-10 Merck Frosst Canada Inc. Antagonistes du leucotriène, leur préparation et compositions les contenant
DE3565400D1 (en) * 1984-02-03 1988-11-10 Ciba Geigy Ag Di-(substituted hydroxyphenylthio)-alkanes and cycloalkanes and compositions containing them
DK0482071T3 (da) * 1989-07-14 1998-09-07 Biodor Us Holding Corp Nye antivirale midler

Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4560799A (en) 1984-02-03 1985-12-24 Ciba-Geigy Corporation Tri- and Tetra-(substituted hydroxyphenylthio) alkane and cycloalkane stabilizers and stabilized compositions
EP0275952A1 (fr) * 1987-01-20 1988-07-27 Merrell Dow Pharmaceuticals Inc. Procédé de la préparation du ditertiobutyl-2,6 mercapto-4 phénol et de l'isopropylidènedithio-4,4'-bis(ditertiobutyl-2,6 phénol)
US5401883A (en) * 1987-01-20 1995-03-28 Merrell Dow Pharmaceuticals Inc. Process for preparing 2,6-di-tertiarybutyl-4-mercaptophenol and 4,4'-isopropylidenedithio-bis-(2,6-di-tertiarybutylphenol)
US4975467A (en) * 1987-03-17 1990-12-04 Merrell Dow Pharmaceuticals Inc. Method of inhibiting interleukin-1 release and alleviating interleukin-1 mediated conditions
US4900757A (en) * 1988-12-08 1990-02-13 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic and antiatherosclerotic uses of bix(3,5-di-tertiary-butyl-4-hydroxyphenylthio)methane
EP0372542A2 (fr) * 1988-12-08 1990-06-13 Merrell Dow Pharmaceuticals Inc. Utilisation hypocholestérolémique et antiathérosclérotique de bis-(3,5-di-tertio-butyl-4-hydroxyphénylthio)méthane
US4954528A (en) * 1988-12-08 1990-09-04 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic use of bis(3,5-di-tertiary-butly-4-hydroxyphenylthio)methane
EP0372542A3 (en) * 1988-12-08 1990-10-17 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic and antiatherosclerotic uses of bis (3,5-di-tertiary-butyl-4-hydroxyphenylthio) methane
US4959392A (en) * 1989-07-24 1990-09-25 Merrell Dow Pharmaceuticals Inc. Method of treating diabetes mellitus
US5962435A (en) * 1993-12-10 1999-10-05 Hoechst Marion Roussel, Inc. Method of lowering serum cholesterol levels with 2,6-di-alkyl-4-silyl-phenols
US5795876A (en) * 1996-04-30 1998-08-18 Hoechst Marion Rousssel, Inc. Method of inhibiting vascular cell adhesion molecule-1 and treating chronic inflammatory diseases with 2, 6-di-alkyl-4-silyl-phenols
US6114572A (en) * 1996-11-20 2000-09-05 Hoechst Marion Roussel, Inc. Substituted phenols and thiophenols useful as antioxidant agents
US6548699B1 (en) 1997-05-14 2003-04-15 Atherogenics, Inc. Compounds and methods for the inhibition of the expression of VCAM-1
EA009370B1 (ru) * 1997-05-14 2007-12-28 Атеродженикс, Инк. Соединение и фармацевтическая композиция для ингибирования экспрессии vcam-1
AU2006202461B2 (en) * 1997-05-14 2009-12-03 Atherogenics, Inc. Compositions and methods for the inhibition of the expression of VCAM-1
US7375252B2 (en) 1997-05-14 2008-05-20 Atherogenics, Inc. Compounds and method for the inhibition of the expression of VCAM-1
WO1998051662A2 (fr) * 1997-05-14 1998-11-19 Atherogenics, Inc. Composes et methodes d'inhibition de l'expression de vcam-1
US6602914B2 (en) 1997-05-14 2003-08-05 Atherogenics, Inc. Compounds and methods for the inhibition of the expression of VCAM-1
US6617352B2 (en) 1997-05-14 2003-09-09 Atherogenics, Inc. Compounds and methods for the inhibition of the expression of VCAM-1
US6670398B2 (en) 1997-05-14 2003-12-30 Atherogenics, Inc. Compounds and methods for treating transplant rejection
US6828447B2 (en) 1997-05-14 2004-12-07 Atherogenics, Inc. Compounds and methods for the inhibition of the expression of VCAM-1
EA009987B1 (ru) * 1997-05-14 2008-04-28 Атеродженикс, Инк. Производные пробукола для лечения заболеваний, опосредованных vcam-1
AU2002300328B2 (en) * 1997-05-14 2006-04-13 Atherogenics, Inc Compounds and methods for the inhibition of the expression of VCAM-1
WO1998051662A3 (fr) * 1997-05-14 2000-03-02 Atherogenics Inc Composes et methodes d'inhibition de l'expression de vcam-1
US7087645B2 (en) 1997-05-14 2006-08-08 Atherogenics, Inc. Compounds and methods for treating transplant rejection
EP1695959A1 (fr) * 1997-05-14 2006-08-30 Atherogenics, Inc. Composes et methodes d'inhibition de l'expression de VCAM-1
US7189870B2 (en) 1997-05-14 2007-03-13 Atherogenic, Inc. Compounds and methods for the inhibition of the expression of VCAM-1
US6121463A (en) * 1997-06-24 2000-09-19 Hoechst Marion Roussel, Inc. Alkyl-4-silylheterocyclic phenols and thiophenols useful as antioxidant agents
US6133467A (en) * 1997-06-25 2000-10-17 Hoechst Marion Roussel, Inc. 2,6-di-t-butyl-4-[(dimethyl-4-methoxyphenylsilyl)-methyl-oxy]phenol and 2,6-di-t-butyl-4-[(dimethyl-2-methoxy-phenylsilyl)methyloxy]phenol
US6852878B2 (en) 1998-05-14 2005-02-08 Atherogenics, Inc. Thioketals and thioethers for inhibiting the expression of VCAM-1
US7294737B2 (en) 2004-04-20 2007-11-13 Atherogenics, Inc. Process of preparing esters and ethers of probucol and derivatives thereof
WO2006063408A1 (fr) * 2004-12-17 2006-06-22 Stocker Ronald O Préparations et méthodes pour le traitement de troubles cardio-vasculaires
US8252840B2 (en) 2007-03-26 2012-08-28 Salutria Pharmaceuticals Llc Methods of derivatives of probucol for the treatment of type II diabetes

Also Published As

Publication number Publication date
FR8063M (fr) 1970-07-06
FR1561853A (fr) 1969-03-28
DE1768334A1 (de) 1971-11-11
DE1768334B2 (de) 1977-10-13
DE1768334C3 (de) 1978-06-01

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Legal Events

Date Code Title Description
PS Patent sealed
PE20 Patent expired after termination of 20 years