GB1194280A - Phenylcyclohexene Carboxylic Acid and Esters and a method for preparing the same - Google Patents
Phenylcyclohexene Carboxylic Acid and Esters and a method for preparing the sameInfo
- Publication number
- GB1194280A GB1194280A GB47358/68A GB4735868A GB1194280A GB 1194280 A GB1194280 A GB 1194280A GB 47358/68 A GB47358/68 A GB 47358/68A GB 4735868 A GB4735868 A GB 4735868A GB 1194280 A GB1194280 A GB 1194280A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carboxylic acid
- phenylcyclohexene
- esters
- diethylamino
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- OSDFYCJQRZZRQZ-UHFFFAOYSA-N 2-phenylcyclohexene-1-carboxylic acid Chemical compound C1CCCC(C(=O)O)=C1C1=CC=CC=C1 OSDFYCJQRZZRQZ-UHFFFAOYSA-N 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- -1 dimethylaminoethyl Chemical group 0.000 abstract 8
- 150000001875 compounds Chemical class 0.000 abstract 4
- 238000006243 chemical reaction Methods 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- VCZPUGSOJXZKIP-UHFFFAOYSA-N 2-hydroxy-2-phenylcyclohexanecarboxylic acid Chemical compound OC(=O)C1CCCCC1(O)C1=CC=CC=C1 VCZPUGSOJXZKIP-UHFFFAOYSA-N 0.000 abstract 1
- FPXFKRJXSSAIMJ-UHFFFAOYSA-N 2-phenylcyclohex-2-ene-1-carboxylic acid Chemical compound OC(=O)C1CCCC=C1C1=CC=CC=C1 FPXFKRJXSSAIMJ-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- MZVQCMJNVPIDEA-UHFFFAOYSA-N [CH2]CN(CC)CC Chemical group [CH2]CN(CC)CC MZVQCMJNVPIDEA-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001663 anti-spastic effect Effects 0.000 abstract 1
- 239000003699 antiulcer agent Substances 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000005809 transesterification reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2136767 | 1967-10-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1194280A true GB1194280A (en) | 1970-06-10 |
Family
ID=11180736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB47358/68A Expired GB1194280A (en) | 1967-10-07 | 1968-10-07 | Phenylcyclohexene Carboxylic Acid and Esters and a method for preparing the same |
Country Status (12)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4229207A (en) * | 1975-08-15 | 1980-10-21 | Ciba-Geigy Corporation | Esters of 1,2-diphenyl-cyclohex-1-ene-4-carboxylic acid |
| IT1213033B (it) * | 1986-02-11 | 1989-12-07 | Guidotti & C Spa Labor | Esteri di n-alchil-nortropine eloro derivati ammonioquaternari aventi attivita'anti-broncospastica, procedimento per la loro preparazione e composizioni farmaceutiche che licontengono. |
-
1968
- 1968-10-03 CH CH1476868A patent/CH533082A/it not_active IP Right Cessation
- 1968-10-03 IL IL30816A patent/IL30816A/xx unknown
- 1968-10-03 DE DE19681800974 patent/DE1800974B2/de active Granted
- 1968-10-04 FR FR42000198A patent/FR8246M/fr not_active Expired
- 1968-10-04 SE SE13423/68A patent/SE356973B/xx unknown
- 1968-10-04 BR BR202854/68A patent/BR6802854D0/pt unknown
- 1968-10-07 BE BE721948A patent/BE721948A/xx unknown
- 1968-10-07 GB GB47358/68A patent/GB1194280A/en not_active Expired
- 1968-10-07 ES ES358926A patent/ES358926A1/es not_active Expired
- 1968-10-07 AT AT09793/68A patent/AT289751B/de not_active IP Right Cessation
- 1968-10-07 DK DK482068AA patent/DK133373B/da unknown
- 1968-10-07 NL NL6814330.A patent/NL161132C/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL161132C (nl) | 1980-01-15 |
| DE1800974B2 (de) | 1973-01-25 |
| DE1800974A1 (de) | 1969-06-04 |
| BR6802854D0 (pt) | 1973-02-22 |
| ES358926A1 (es) | 1970-05-16 |
| IL30816A (en) | 1973-04-30 |
| NL6814330A (enrdf_load_stackoverflow) | 1969-04-09 |
| IL30816A0 (en) | 1968-12-26 |
| DE1800974C3 (enrdf_load_stackoverflow) | 1973-09-13 |
| DK133373C (enrdf_load_stackoverflow) | 1976-10-11 |
| BE721948A (enrdf_load_stackoverflow) | 1969-03-14 |
| CH533082A (it) | 1973-01-31 |
| NL161132B (nl) | 1979-08-15 |
| SE356973B (enrdf_load_stackoverflow) | 1973-06-12 |
| AT289751B (de) | 1971-03-15 |
| DK133373B (da) | 1976-05-10 |
| FR8246M (enrdf_load_stackoverflow) | 1970-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |