GB1192701A - Novel Thiazole Derivatives, the preparation thereof and Compositions containing the same - Google Patents

Novel Thiazole Derivatives, the preparation thereof and Compositions containing the same

Info

Publication number
GB1192701A
GB1192701A GB03989/68A GB1398968A GB1192701A GB 1192701 A GB1192701 A GB 1192701A GB 03989/68 A GB03989/68 A GB 03989/68A GB 1398968 A GB1398968 A GB 1398968A GB 1192701 A GB1192701 A GB 1192701A
Authority
GB
United Kingdom
Prior art keywords
agent
compositions
alkyl group
hydrogen atom
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB03989/68A
Other languages
English (en)
Inventor
Walter Hepworth
Gilbert Joseph Stacey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Priority to GB03989/68A priority Critical patent/GB1192701A/en
Priority to BR207374/68A priority patent/BR6807374D0/pt
Priority to US799963A priority patent/US3661920A/en
Priority to IE209/69A priority patent/IE32967B1/xx
Priority to IL31679A priority patent/IL31679A/en
Priority to CA043,831A priority patent/CA948199A/en
Priority to AT251269A priority patent/AT284841B/de
Priority to NL6903963A priority patent/NL6903963A/xx
Priority to DE19691913472 priority patent/DE1913472A1/de
Priority to CS810072*1A priority patent/CS154268B2/cs
Priority to CS193669A priority patent/CS154266B2/cs
Priority to CS809972*1A priority patent/CS154267B2/cs
Priority to BE730284D priority patent/BE730284A/xx
Priority to CH806271A priority patent/CH513910A/de
Priority to FR6908408A priority patent/FR2004544A1/fr
Priority to CH434369A priority patent/CH513907A/de
Priority to CH806371A priority patent/CH553209A/de
Priority to DK157569AA priority patent/DK125251B/da
Priority to ES365089A priority patent/ES365089A1/es
Priority to JP44021555A priority patent/JPS4810467B1/ja
Publication of GB1192701A publication Critical patent/GB1192701A/en
Priority to DK498870AA priority patent/DK125326B/da
Priority to DK498970AA priority patent/DK122393B/da
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
GB03989/68A 1968-03-22 1968-03-22 Novel Thiazole Derivatives, the preparation thereof and Compositions containing the same Expired GB1192701A (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
GB03989/68A GB1192701A (en) 1968-03-22 1968-03-22 Novel Thiazole Derivatives, the preparation thereof and Compositions containing the same
BR207374/68A BR6807374D0 (pt) 1968-03-22 1968-03-23 Novo derivado tiazole processo para preparacao dos mesmos e composicoes farmaceuticas contendo ditos compostos
US799963A US3661920A (en) 1968-03-22 1969-02-17 Phenyl-thiazole-malonic acid derivatives
IE209/69A IE32967B1 (en) 1968-03-22 1969-02-18 Novel thiazole derivatives,the preparation thereof and compositions containing the same
IL31679A IL31679A (en) 1968-03-22 1969-02-23 History of thiazole
CA043,831A CA948199A (en) 1968-03-22 1969-02-24 Heterocyclic compounds
AT251269A AT284841B (de) 1968-03-22 1969-03-14 Verfahren zur Herstellung von neuen Thiazolderivaten von deren Salzen
NL6903963A NL6903963A (de) 1968-03-22 1969-03-14
DE19691913472 DE1913472A1 (de) 1968-03-22 1969-03-17 Thiazolderivat und Verfahren zu dessen Herstellung
CS809972*1A CS154267B2 (de) 1968-03-22 1969-03-18
CS193669A CS154266B2 (de) 1968-03-22 1969-03-18
CS810072*1A CS154268B2 (de) 1968-03-22 1969-03-18
CH806371A CH553209A (de) 1968-03-22 1969-03-21 Verfahren zur herstellung neuer (alpha)-thiazolyl-(alpha)-alkylmalonsaeureester.
CH806271A CH513910A (de) 1968-03-22 1969-03-21 Verfahren zur Herstellung neuer Thiazolderivate
FR6908408A FR2004544A1 (de) 1968-03-22 1969-03-21
CH434369A CH513907A (de) 1968-03-22 1969-03-21 Verfahren zur Herstellung neuer Thiazolderivate
BE730284D BE730284A (de) 1968-03-22 1969-03-21
DK157569AA DK125251B (da) 1968-03-22 1969-03-21 Analogifremgangsmåde til fremstilling af thiazolylmalonsyrederivater.
ES365089A ES365089A1 (es) 1968-03-22 1969-03-22 Procedimiento para la preparacion de derivados tiazolicos.
JP44021555A JPS4810467B1 (de) 1968-03-22 1969-03-22
DK498870AA DK125326B (da) 1968-03-22 1970-09-30 Analogifremgangsmåde til fremstilling af phenylthiazol-2-ylmalonsyrederivater.
DK498970AA DK122393B (da) 1968-03-22 1970-09-30 Analogifremgangsmåde til fremstilling af phenylthiazolyl-α-alkylmalonsyrederivater.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB03989/68A GB1192701A (en) 1968-03-22 1968-03-22 Novel Thiazole Derivatives, the preparation thereof and Compositions containing the same

Publications (1)

Publication Number Publication Date
GB1192701A true GB1192701A (en) 1970-05-20

Family

ID=10033003

Family Applications (1)

Application Number Title Priority Date Filing Date
GB03989/68A Expired GB1192701A (en) 1968-03-22 1968-03-22 Novel Thiazole Derivatives, the preparation thereof and Compositions containing the same

Country Status (15)

Country Link
US (1) US3661920A (de)
AT (1) AT284841B (de)
BE (1) BE730284A (de)
BR (1) BR6807374D0 (de)
CA (1) CA948199A (de)
CH (2) CH513907A (de)
CS (3) CS154266B2 (de)
DE (1) DE1913472A1 (de)
DK (3) DK125251B (de)
ES (1) ES365089A1 (de)
FR (1) FR2004544A1 (de)
GB (1) GB1192701A (de)
IE (1) IE32967B1 (de)
IL (1) IL31679A (de)
NL (1) NL6903963A (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4371734A (en) 1978-01-17 1983-02-01 Basf Aktiengesellschaft Preparation of thiazole derivatives

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2703542C2 (de) * 1977-01-26 1985-09-26 Schering AG, 1000 Berlin und 4709 Bergkamen Thiazolylzimtsäurenitrile, Insektenbekämpfungsmittel enthaltend diese Verbindungen sowie Verfahren zu ihrer Herstellung
US4153703A (en) * 1977-06-30 1979-05-08 Uniroyal, Inc. Method of controlling insects and acarids with certain aryl-substituted thiazoles
US4197306A (en) * 1977-06-30 1980-04-08 Uniroyal, Inc. Aryl-substituted thiazoles
DE2920183A1 (de) * 1979-05-17 1981-04-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Thiazolyliden-oxo-propionitrile, insektizide mittel enthaltend diese verbindungen sowie verfahren zu ihrer herstellung
US4346094A (en) * 1980-09-22 1982-08-24 Eli Lilly And Company 3-Aryl-5-isothiazolecarboxylic acids and related compounds used to lower uric acid levels
US5077305A (en) * 1990-02-13 1991-12-31 Bristol-Myers Squibb Co. Thiazole carboxylic acids and esters
EP0442448A3 (en) 1990-02-13 1992-08-12 Bristol-Myers Squibb Company Heterocyclic carboxylic acids and esters
DE10331675A1 (de) * 2003-07-14 2005-02-10 Bayer Cropscience Ag Hetarylsubstituierte Pyrazolidindion-Derivate
WO2009052454A2 (en) * 2007-10-19 2009-04-23 University Of California Compositions and methods for ameliorating cns inflammation, psychosis, delirium, ptsd or ptss

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4371734A (en) 1978-01-17 1983-02-01 Basf Aktiengesellschaft Preparation of thiazole derivatives

Also Published As

Publication number Publication date
NL6903963A (de) 1969-09-24
BE730284A (de) 1969-09-22
ES365089A1 (es) 1971-01-01
CA948199A (en) 1974-05-28
IE32967L (en) 1969-09-22
CH553209A (de) 1974-08-30
DE1913472A1 (de) 1969-11-06
CS154268B2 (de) 1974-03-29
DK125251B (da) 1973-01-22
US3661920A (en) 1972-05-09
AT284841B (de) 1970-09-25
BR6807374D0 (pt) 1973-02-08
DK125326B (da) 1973-02-05
CH513907A (de) 1971-10-15
IL31679A (en) 1972-08-30
CS154267B2 (de) 1974-03-29
DK122393B (da) 1972-02-28
IE32967B1 (en) 1974-02-06
FR2004544A1 (de) 1969-11-28
CS154266B2 (de) 1974-03-29

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees