GB1183135A - 2,4-Benzodiazepines, process for their manufacture and Compositions containing them - Google Patents

2,4-Benzodiazepines, process for their manufacture and Compositions containing them

Info

Publication number
GB1183135A
GB1183135A GB1694368A GB1694368A GB1183135A GB 1183135 A GB1183135 A GB 1183135A GB 1694368 A GB1694368 A GB 1694368A GB 1694368 A GB1694368 A GB 1694368A GB 1183135 A GB1183135 A GB 1183135A
Authority
GB
United Kingdom
Prior art keywords
aliphatic
araliphatic
heteroaryl
aromatic
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1694368A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
Original Assignee
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba AG filed Critical Ciba AG
Publication of GB1183135A publication Critical patent/GB1183135A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/04Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB1694368A 1967-04-13 1968-04-09 2,4-Benzodiazepines, process for their manufacture and Compositions containing them Expired GB1183135A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63049767A 1967-04-13 1967-04-13
US69442167A 1967-12-29 1967-12-29

Publications (1)

Publication Number Publication Date
GB1183135A true GB1183135A (en) 1970-03-04

Family

ID=27091165

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1694368A Expired GB1183135A (en) 1967-04-13 1968-04-09 2,4-Benzodiazepines, process for their manufacture and Compositions containing them

Country Status (5)

Country Link
BE (1) BE713698A (de)
CH (3) CH523264A (de)
DE (1) DE1770135A1 (de)
FR (2) FR1588463A (de)
GB (1) GB1183135A (de)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU639821B2 (en) * 1990-09-10 1993-08-05 Sanofi Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents
EP0597540A1 (de) * 1992-11-10 1994-05-18 Sterling Winthrop Inc. Aryl und Hetaryl annelierte 2,4-Diazocine als anti-arryhthmische Wirkstoffe
US5380721A (en) * 1990-09-10 1995-01-10 Sterling Winthrop Inc. Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents
WO1996019440A1 (en) * 1994-12-20 1996-06-27 The Wellcome Foundation Limited Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase
JP2009513656A (ja) * 2005-10-27 2009-04-02 シェーリング コーポレイション 複素環式アスパルチルプロテアーゼインヒビター
CN101671307A (zh) * 2003-12-15 2010-03-17 先灵公司 杂环天冬氨酰蛋白酶抑制剂

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU639821B2 (en) * 1990-09-10 1993-08-05 Sanofi Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents
US5380721A (en) * 1990-09-10 1995-01-10 Sterling Winthrop Inc. Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents
US5624922A (en) * 1990-09-10 1997-04-29 Sterling Winthrop Inc. Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents
EP0597540A1 (de) * 1992-11-10 1994-05-18 Sterling Winthrop Inc. Aryl und Hetaryl annelierte 2,4-Diazocine als anti-arryhthmische Wirkstoffe
WO1996019440A1 (en) * 1994-12-20 1996-06-27 The Wellcome Foundation Limited Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase
US5866612A (en) * 1994-12-20 1999-02-02 Glaxo Wellcome Inc. Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase
USRE37438E1 (en) 1994-12-20 2001-11-06 Glaxo Wellcome Inc. Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase
CN101671307A (zh) * 2003-12-15 2010-03-17 先灵公司 杂环天冬氨酰蛋白酶抑制剂
CN102627609A (zh) * 2003-12-15 2012-08-08 先灵公司 杂环天冬氨酰蛋白酶抑制剂
CN101671307B (zh) * 2003-12-15 2014-05-14 默沙东公司 杂环天冬氨酰蛋白酶抑制剂
CN102627609B (zh) * 2003-12-15 2016-05-04 默沙东公司 杂环天冬氨酰蛋白酶抑制剂
JP2009513656A (ja) * 2005-10-27 2009-04-02 シェーリング コーポレイション 複素環式アスパルチルプロテアーゼインヒビター

Also Published As

Publication number Publication date
BE713698A (de) 1968-10-14
FR1588463A (de) 1970-04-17
DE1770135A1 (de) 1971-09-23
CH527828A (de) 1972-09-15
CH523264A (de) 1972-05-31
FR7495M (de) 1969-12-08
CH511863A (de) 1971-08-31

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees