GB1180862A - 2-[(Halophenoxy)Methyl]-2-Imidazolines - Google Patents
2-[(Halophenoxy)Methyl]-2-ImidazolinesInfo
- Publication number
- GB1180862A GB1180862A GB1606068A GB1606068A GB1180862A GB 1180862 A GB1180862 A GB 1180862A GB 1606068 A GB1606068 A GB 1606068A GB 1606068 A GB1606068 A GB 1606068A GB 1180862 A GB1180862 A GB 1180862A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- defined above
- methyl
- compounds
- bromine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 title abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 4
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 4
- 125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 abstract 4
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 4
- 229910052794 bromium Inorganic materials 0.000 abstract 4
- 229910052801 chlorine Inorganic materials 0.000 abstract 4
- 239000000460 chlorine Substances 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000003301 hydrolyzing effect Effects 0.000 abstract 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 3
- -1 2 - (substituted phenoxymethyl) - 2 - imidazoline compounds Chemical class 0.000 abstract 2
- HVCCFMAPGCBCHZ-UHFFFAOYSA-N 2-aminoethylazanium;4-methylbenzenesulfonate Chemical compound NCCN.CC1=CC=C(S(O)(=O)=O)C=C1 HVCCFMAPGCBCHZ-UHFFFAOYSA-N 0.000 abstract 2
- VLLSCJFPVSQXDM-UHFFFAOYSA-N 2-phenoxyacetonitrile Chemical class N#CCOC1=CC=CC=C1 VLLSCJFPVSQXDM-UHFFFAOYSA-N 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- UMPSXRYVXUPCOS-UHFFFAOYSA-N 2,3-dichlorophenol Chemical compound OC1=CC=CC(Cl)=C1Cl UMPSXRYVXUPCOS-UHFFFAOYSA-N 0.000 abstract 1
- ROFYLHXAHQGEED-UHFFFAOYSA-N 2-(2,6-dichloro-3-methylphenoxy)acetonitrile Chemical compound ClC1=C(OCC#N)C(=CC=C1C)Cl ROFYLHXAHQGEED-UHFFFAOYSA-N 0.000 abstract 1
- RENMDAKOXSCIGH-UHFFFAOYSA-N Chloroacetonitrile Chemical compound ClCC#N RENMDAKOXSCIGH-UHFFFAOYSA-N 0.000 abstract 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 229960001760 dimethyl sulfoxide Drugs 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000857 drug effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- ILUDQMOIIQHYDU-UHFFFAOYSA-N ethyl 2-(2,6-dichloro-3-methylphenoxy)ethanimidate hydrochloride Chemical compound Cl.C(C)OC(COC1=C(C(=CC=C1Cl)C)Cl)=N ILUDQMOIIQHYDU-UHFFFAOYSA-N 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 239000007928 intraperitoneal injection Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000001428 peripheral nervous system Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000009738 saturating Methods 0.000 abstract 1
- 125000005490 tosylate group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/22—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4509169A GB1187200A (en) | 1967-04-04 | 1968-04-03 | 2-[(Halophenoxy) Methyl]-2-Imidazolines |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62830167A | 1967-04-04 | 1967-04-04 | |
| US62830267A | 1967-04-04 | 1967-04-04 | |
| US62830367A | 1967-04-04 | 1967-04-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1180862A true GB1180862A (en) | 1970-02-11 |
Family
ID=27417443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1606068A Expired GB1180862A (en) | 1967-04-04 | 1968-04-03 | 2-[(Halophenoxy)Methyl]-2-Imidazolines |
Country Status (11)
| Country | Link |
|---|---|
| CH (1) | CH505832A (enrdf_load_stackoverflow) |
| DE (1) | DE1770104C3 (enrdf_load_stackoverflow) |
| DK (1) | DK135452B (enrdf_load_stackoverflow) |
| FI (1) | FI49613C (enrdf_load_stackoverflow) |
| FR (2) | FR1579552A (enrdf_load_stackoverflow) |
| GB (1) | GB1180862A (enrdf_load_stackoverflow) |
| IL (1) | IL29692A (enrdf_load_stackoverflow) |
| NL (1) | NL160255C (enrdf_load_stackoverflow) |
| NO (1) | NO122481B (enrdf_load_stackoverflow) |
| SE (1) | SE342626B (enrdf_load_stackoverflow) |
| YU (1) | YU33690B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0374757A1 (de) * | 1988-12-20 | 1990-06-27 | Hoechst Aktiengesellschaft | Imidazolinderivate enthaltende Mittel zur wirtstiersystemischen Bekämpfung von Ektoparasiten sowie neue Imidazolinderivate |
-
1968
- 1968-03-22 NO NO111968A patent/NO122481B/no unknown
- 1968-03-26 IL IL2969268A patent/IL29692A/en unknown
- 1968-04-01 DE DE19681770104 patent/DE1770104C3/de not_active Expired
- 1968-04-01 SE SE428068A patent/SE342626B/xx unknown
- 1968-04-03 GB GB1606068A patent/GB1180862A/en not_active Expired
- 1968-04-03 NL NL6804672A patent/NL160255C/xx not_active IP Right Cessation
- 1968-04-03 DK DK146768A patent/DK135452B/da not_active IP Right Cessation
- 1968-04-03 CH CH488468A patent/CH505832A/de not_active IP Right Cessation
- 1968-04-03 YU YU76568A patent/YU33690B/xx unknown
- 1968-04-03 FR FR1579552D patent/FR1579552A/fr not_active Expired
- 1968-04-04 FI FI93368A patent/FI49613C/fi active
- 1968-07-03 FR FR157620A patent/FR7668M/fr not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0374757A1 (de) * | 1988-12-20 | 1990-06-27 | Hoechst Aktiengesellschaft | Imidazolinderivate enthaltende Mittel zur wirtstiersystemischen Bekämpfung von Ektoparasiten sowie neue Imidazolinderivate |
| US5128361A (en) * | 1988-12-20 | 1992-07-07 | Hoechst Aktiengesellschaft | Imidazoline derivatives for systemic combating of ectoparasites in host animals |
Also Published As
| Publication number | Publication date |
|---|---|
| NL6804672A (enrdf_load_stackoverflow) | 1968-10-07 |
| DK135452B (da) | 1977-05-02 |
| DK135452C (enrdf_load_stackoverflow) | 1977-10-17 |
| SE342626B (enrdf_load_stackoverflow) | 1972-02-14 |
| DE1770104C3 (de) | 1979-08-23 |
| YU33690B (en) | 1978-02-28 |
| DE1770104B2 (de) | 1978-11-23 |
| FI49613C (fi) | 1975-08-11 |
| FI49613B (enrdf_load_stackoverflow) | 1975-04-30 |
| CH505832A (de) | 1971-04-15 |
| IL29692A (en) | 1971-08-25 |
| FR1579552A (enrdf_load_stackoverflow) | 1969-08-29 |
| NL160255C (nl) | 1979-10-15 |
| FR7668M (enrdf_load_stackoverflow) | 1970-02-09 |
| NL160255B (nl) | 1979-05-15 |
| DE1770104A1 (de) | 1971-09-23 |
| NO122481B (enrdf_load_stackoverflow) | 1971-07-05 |
| YU76568A (en) | 1977-08-31 |
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