GB1173540A - Benzodiazepine Derivatives - Google Patents

Benzodiazepine Derivatives

Info

Publication number
GB1173540A
GB1173540A GB55844/68A GB5584468A GB1173540A GB 1173540 A GB1173540 A GB 1173540A GB 55844/68 A GB55844/68 A GB 55844/68A GB 5584468 A GB5584468 A GB 5584468A GB 1173540 A GB1173540 A GB 1173540A
Authority
GB
United Kingdom
Prior art keywords
halogen
methyl
ethyl
ethoxy
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB55844/68A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Boehringer Ingelheim GmbH
Original Assignee
CH Boehringer Sohn AG and Co KG
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG, Boehringer Ingelheim GmbH filed Critical CH Boehringer Sohn AG and Co KG
Publication of GB1173540A publication Critical patent/GB1173540A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
GB55844/68A 1967-11-24 1968-11-25 Benzodiazepine Derivatives Expired GB1173540A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1064767A AT280290B (de) 1967-11-24 1967-11-24 Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen

Publications (1)

Publication Number Publication Date
GB1173540A true GB1173540A (en) 1969-12-10

Family

ID=3623762

Family Applications (1)

Application Number Title Priority Date Filing Date
GB55844/68A Expired GB1173540A (en) 1967-11-24 1968-11-25 Benzodiazepine Derivatives

Country Status (13)

Country Link
AT (1) AT280290B (xx)
BE (1) BE724364A (xx)
BR (1) BR6804236D0 (xx)
CH (1) CH523265A (xx)
DE (1) DE1810423B2 (xx)
DK (1) DK124950B (xx)
ES (2) ES360410A1 (xx)
FR (2) FR1593335A (xx)
GB (1) GB1173540A (xx)
IE (1) IE32504B1 (xx)
IL (1) IL31146A (xx)
NL (1) NL6815755A (xx)
SE (1) SE356979B (xx)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU782447B2 (en) * 1999-04-30 2005-07-28 Regents Of The University Of Michigan, The Use of benzodiazepines for treating autoimmune diseases induced by apoptosis
EP2146722A1 (en) * 2007-05-10 2010-01-27 AMR Technology, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
JP2016530317A (ja) * 2013-09-11 2016-09-29 ジ・アドミニストレーターズ・オブ・ザ・チューレーン・エデュケーショナル・ファンド 新規アントラニルアミドとその使用

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914216A (en) * 1962-12-18 1975-10-21 Boehringer Sohn Ingelheim 1-Phenyl-3H-1,4-benzodiazepine-2,5-(1H,4H)-diones
DE2117438A1 (de) * 1971-04-08 1972-10-19 CH. Boehringer Sohn, 6507 Ingelheim Neue substituiert 1,3-Dihydro-2H-1 ^-benzodiazepine^-one
BE793460A (fr) * 1971-12-29 1973-06-28 Boehringer Sohn Ingelheim Nouvelles 1-aryl-3h,1,4-benzodiazepine-2,5-(1h
US20060025388A1 (en) 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
US7276348B2 (en) 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US7572788B2 (en) 1999-04-30 2009-08-11 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US7691582B2 (en) 2002-09-27 2010-04-06 The Regents Of The University Of Michigan Methods of secretory vimentin detection and modulation
AU2006203946B2 (en) 2005-01-03 2009-07-23 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
JP2008545757A (ja) 2005-06-01 2008-12-18 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 溶媒和されていないベンゾジアゼピン組成物および方法
EP1948191B1 (en) 2005-11-01 2013-01-16 The Regents of the University of Michigan Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties
US7759338B2 (en) 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
US8097612B2 (en) 2006-06-09 2012-01-17 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
CA2783589A1 (en) 2007-03-09 2008-09-18 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
CN101855203B (zh) 2007-09-14 2014-03-19 密执安州立大学董事会 F1f0-atp合成酶抑制剂以及相关的方法
NZ584842A (en) 2007-11-06 2012-06-29 Univ Michigan Benzodiazepinone compounds useful in the treatment of skin conditions, in particular, psoriasis
US8497307B2 (en) 2008-09-11 2013-07-30 The Regents Of The University Of Michigan Aryl guanidine F1F0-ATPase inhibitors and related methods
WO2010121164A2 (en) 2009-04-17 2010-10-21 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
JP2013505258A (ja) 2009-09-18 2013-02-14 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン ベンゾジアゼピノン化合物およびそれを使用する治療方法
CA2780333C (en) 2009-11-17 2016-05-24 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
ES2703752T3 (es) 2009-11-17 2019-03-12 Univ Michigan Regents 1,4-Benzodiazepina-2,5-dionas y compuestos relacionados que presentan propiedades terapéuticas

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU782447B2 (en) * 1999-04-30 2005-07-28 Regents Of The University Of Michigan, The Use of benzodiazepines for treating autoimmune diseases induced by apoptosis
AU782447C (en) * 1999-04-30 2006-07-13 Regents Of The University Of Michigan, The Use of benzodiazepines for treating autoimmune diseases induced by apoptosis
EP2146722A1 (en) * 2007-05-10 2010-01-27 AMR Technology, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
EP2146722A4 (en) * 2007-05-10 2011-08-03 Amr Technology Inc ARYL AND HETEROARYL SUBSTITUTED TETRAHYDROBENZO-1,4-DIAZEPINES AND THEIR USE FOR BLOCKING THE RECOVERY OF NOREPINEPHRIN, DOPAMINE AND SEROTONINE
US9096546B2 (en) 2007-05-10 2015-08-04 Albany Molecular Research, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
JP2016530317A (ja) * 2013-09-11 2016-09-29 ジ・アドミニストレーターズ・オブ・ザ・チューレーン・エデュケーショナル・ファンド 新規アントラニルアミドとその使用
US11465978B2 (en) 2013-09-11 2022-10-11 The Administrators Of The Tulane Educational Fund Anthranilic amides and the use thereof

Also Published As

Publication number Publication date
FR1593335A (xx) 1970-05-25
DE1810423A1 (de) 1969-10-09
DE1810423C3 (xx) 1973-10-11
NL6815755A (xx) 1969-05-28
CH523265A (de) 1972-05-31
FR8310M (xx) 1970-11-23
DK124950B (da) 1972-12-11
IE32504L (en) 1969-05-24
BR6804236D0 (pt) 1973-02-08
ES378977A1 (es) 1973-01-16
BE724364A (xx) 1969-05-22
AT280290B (de) 1970-04-10
DE1810423B2 (de) 1973-03-22
IL31146A0 (en) 1969-01-29
IE32504B1 (en) 1973-08-22
IL31146A (en) 1972-04-27
SE356979B (xx) 1973-06-12
ES360410A1 (es) 1970-11-01

Similar Documents

Publication Publication Date Title
GB1173540A (en) Benzodiazepine Derivatives
GB1432576A (en) Substituted phenylacetic acids
GB1200886A (en) Phenylaminoethanol derivatives
IE36947B1 (en) New esters their production and their medicinal use
GB1474882A (en) Alpha-aminomethyl-5-hydroxy-2-pyridinemethanols
GB1481219A (en) Preparation of benzodiazepines
GB1410755A (en) Tricyclic substituted aminoalcohols and the preparation thereof
GB1456627A (en) Pyridobenzodiazepinones
GB1188846A (en) Thiazole Derivatives
GB1443692A (en) 1,2-diphenylethanolamine derivatives and their salts and the preparation thereof
GB1434805A (en) 5-phenoxy-4-amino pyrimidines
GB984471A (en) Anthranilic acid esters and methods for producing the same
ES8502118A1 (es) Procedimiento de preparar derivados de penicilina.
GB1235399A (en) Polymethylene diamine derivatives
GB1462095A (en) Substituted triazolo-1,5-benzodiazepines
ES376688A1 (es) Procedimiento para la produccion de una 3h-1,4-benzodiacepi-ra.
GB1494560A (en) 4-aryl-5-aminoalkyl-4-thiazolin-2-ones and their preparation
JPS5273876A (en) Synthesis of carbostyril derivatives
GB1468079A (en) Ethanolamine derivatives
GB1184826A (en) Substituted Aryloxy Hydroxy Amines
ES363591A1 (es) Un procedimiento para la produccion de derivados de fenile-tilamina.
GB1364723A (en) Decahydroquinolinol derivatives and process for preparing the sa me
GB1384684A (en) 1,3,5-triazine and process for the preparation thereof
GB1395772A (en) 1-aryl-3h-1,4-benzodiazepin-2,5-1h,4h-diones
GB1446164A (en) Basic enol ethers their salts processes for their preparation and pharmaceutical preparations containing the same

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee