DK124950B - Analogifremgangsmåde til fremstilling af 1-phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dioner. - Google Patents

Analogifremgangsmåde til fremstilling af 1-phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dioner.

Info

Publication number
DK124950B
DK124950B DK566968AA DK566968A DK124950B DK 124950 B DK124950 B DK 124950B DK 566968A A DK566968A A DK 566968AA DK 566968 A DK566968 A DK 566968A DK 124950 B DK124950 B DK 124950B
Authority
DK
Denmark
Prior art keywords
diones
benzodiazepine
phenyl
alkyl
preparation
Prior art date
Application number
DK566968AA
Other languages
Danish (da)
English (en)
Inventor
K Zeile
R Giesemann
K Weber
P Danneberg
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of DK124950B publication Critical patent/DK124950B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
DK566968AA 1967-11-24 1968-11-20 Analogifremgangsmåde til fremstilling af 1-phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dioner. DK124950B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1064767A AT280290B (de) 1967-11-24 1967-11-24 Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen

Publications (1)

Publication Number Publication Date
DK124950B true DK124950B (da) 1972-12-11

Family

ID=3623762

Family Applications (1)

Application Number Title Priority Date Filing Date
DK566968AA DK124950B (da) 1967-11-24 1968-11-20 Analogifremgangsmåde til fremstilling af 1-phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dioner.

Country Status (13)

Country Link
AT (1) AT280290B (xx)
BE (1) BE724364A (xx)
BR (1) BR6804236D0 (xx)
CH (1) CH523265A (xx)
DE (1) DE1810423B2 (xx)
DK (1) DK124950B (xx)
ES (2) ES360410A1 (xx)
FR (2) FR1593335A (xx)
GB (1) GB1173540A (xx)
IE (1) IE32504B1 (xx)
IL (1) IL31146A (xx)
NL (1) NL6815755A (xx)
SE (1) SE356979B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914216A (en) * 1962-12-18 1975-10-21 Boehringer Sohn Ingelheim 1-Phenyl-3H-1,4-benzodiazepine-2,5-(1H,4H)-diones
DE2117438A1 (de) * 1971-04-08 1972-10-19 CH. Boehringer Sohn, 6507 Ingelheim Neue substituiert 1,3-Dihydro-2H-1 ^-benzodiazepine^-one
BE793460A (fr) * 1971-12-29 1973-06-28 Boehringer Sohn Ingelheim Nouvelles 1-aryl-3h,1,4-benzodiazepine-2,5-(1h
CA2372150C (en) * 1999-04-30 2011-08-30 The Regents Of The University Of Michigan Therapeutic applications of pro-apoptotic benzodiazepines
US20060025388A1 (en) 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
US7276348B2 (en) 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US7572788B2 (en) 1999-04-30 2009-08-11 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US7691582B2 (en) 2002-09-27 2010-04-06 The Regents Of The University Of Michigan Methods of secretory vimentin detection and modulation
AU2006203946B2 (en) 2005-01-03 2009-07-23 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
JP2008545757A (ja) 2005-06-01 2008-12-18 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 溶媒和されていないベンゾジアゼピン組成物および方法
EP1948191B1 (en) 2005-11-01 2013-01-16 The Regents of the University of Michigan Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties
US7759338B2 (en) 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
US8097612B2 (en) 2006-06-09 2012-01-17 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
CA2783589A1 (en) 2007-03-09 2008-09-18 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
BRPI0811204A8 (pt) 2007-05-10 2015-09-22 Bristol Myers Squibb Co Tetra-hidroibenzo-1,4-diazepinas substituídas por arila e heteroarila e uso das mesmas para bloquear a recaptação de norepinefrina, dopamina e serotonina
CN101855203B (zh) 2007-09-14 2014-03-19 密执安州立大学董事会 F1f0-atp合成酶抑制剂以及相关的方法
NZ584842A (en) 2007-11-06 2012-06-29 Univ Michigan Benzodiazepinone compounds useful in the treatment of skin conditions, in particular, psoriasis
US8497307B2 (en) 2008-09-11 2013-07-30 The Regents Of The University Of Michigan Aryl guanidine F1F0-ATPase inhibitors and related methods
WO2010121164A2 (en) 2009-04-17 2010-10-21 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
JP2013505258A (ja) 2009-09-18 2013-02-14 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン ベンゾジアゼピノン化合物およびそれを使用する治療方法
CA2780333C (en) 2009-11-17 2016-05-24 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
ES2703752T3 (es) 2009-11-17 2019-03-12 Univ Michigan Regents 1,4-Benzodiazepina-2,5-dionas y compuestos relacionados que presentan propiedades terapéuticas
CA2923835C (en) 2013-09-11 2022-11-29 The Administrators Of The Tulane Educational Fund Novel anthranilic amides and the use thereof

Also Published As

Publication number Publication date
FR1593335A (xx) 1970-05-25
DE1810423A1 (de) 1969-10-09
DE1810423C3 (xx) 1973-10-11
NL6815755A (xx) 1969-05-28
CH523265A (de) 1972-05-31
FR8310M (xx) 1970-11-23
IE32504L (en) 1969-05-24
BR6804236D0 (pt) 1973-02-08
ES378977A1 (es) 1973-01-16
BE724364A (xx) 1969-05-22
AT280290B (de) 1970-04-10
DE1810423B2 (de) 1973-03-22
IL31146A0 (en) 1969-01-29
GB1173540A (en) 1969-12-10
IE32504B1 (en) 1973-08-22
IL31146A (en) 1972-04-27
SE356979B (xx) 1973-06-12
ES360410A1 (es) 1970-11-01

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