GB1155530A - Imidazole Derivatives, their Preparation and Compositions containing them - Google Patents
Imidazole Derivatives, their Preparation and Compositions containing themInfo
- Publication number
- GB1155530A GB1155530A GB38884/68A GB3888468A GB1155530A GB 1155530 A GB1155530 A GB 1155530A GB 38884/68 A GB38884/68 A GB 38884/68A GB 3888468 A GB3888468 A GB 3888468A GB 1155530 A GB1155530 A GB 1155530A
- Authority
- GB
- United Kingdom
- Prior art keywords
- nitro
- general formula
- alkoxy
- alkyl
- imidazole derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Devices For Checking Fares Or Tickets At Control Points (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
1,155,530. Imidazole derivatives. MERCK & CO. Inc. 4 July, 1966 [7 July, 1965; 18 May, 1966], No. 38884/68. Divided out of 1,153,347. Heading C2C. Novel imidazole derivatives of the general formula wherein W is nitro, cyano, phenyl or hydrogen; and P is hydrogen or nitro, provided that one and only one of W and P is nitro; M is oxygen or sulphur; X is chloro; Q is C 1-5 alkylene, C 2-5 alkenylene, phenyl-substituted C 1-5 alkylene or C 2-5 alkylidene; R 1 is an alkyl radical, either unsubstituted or having a hydroxy, oxo, alkanoyloxy, aralkanoyloxy, alkoxy, aralkoxy, alkoxycarbonyl, aralkoxycarbonyl, cyano, alkylthio, aralkylthio, alkylsulphinyl, aralkylsulphinyl, arylsulphinyl, alkylsulphonyl, aralkylsulphonyl, arylsulphonyl, halo, alkenyl or dialkylamino substituent, the terms " alkyl" " alkanoyl " and " alkoxy " meaning C 1-5 alkyl, C 1-5 alkanoyl and C 1-5 alkoxy groups, respectively, are prepared by reaction of an imidazole derivative of the general formula with phosgene or thiophosgene. Pharmaceutical compositions, useful against parasitic diseases, amoebiasis, trypanosomiasis and chronic respiratory diseases in fowl and also showing antibacterial activity, comprise as active ingredient an imidazole derivative of the first general formula above and an inert diluent, carrier or coating.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47023965A | 1965-07-07 | 1965-07-07 | |
| US55093266A | 1966-05-18 | 1966-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1155530A true GB1155530A (en) | 1969-06-18 |
Family
ID=27043018
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB35039/68A Expired GB1155529A (en) | 1965-07-07 | 1966-07-04 | Imidazole derivatives, their Preparation and Compositions containing them |
| GB32952/68A Expired GB1155528A (en) | 1965-07-07 | 1966-07-04 | Imidazole derivatives, their Preparation and Compositions containing them |
| GB29846/66A Expired GB1153347A (en) | 1965-07-07 | 1966-07-04 | Imidazole Derivatives, their preparation and Compositions containing them. |
| GB38884/68A Expired GB1155530A (en) | 1965-07-07 | 1966-07-04 | Imidazole Derivatives, their Preparation and Compositions containing them |
| GB35033/68A Expired GB1154290A (en) | 1965-07-07 | 1966-07-04 | Imidazole Derivatives, their preparation and compositions containing them |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB35039/68A Expired GB1155529A (en) | 1965-07-07 | 1966-07-04 | Imidazole derivatives, their Preparation and Compositions containing them |
| GB32952/68A Expired GB1155528A (en) | 1965-07-07 | 1966-07-04 | Imidazole derivatives, their Preparation and Compositions containing them |
| GB29846/66A Expired GB1153347A (en) | 1965-07-07 | 1966-07-04 | Imidazole Derivatives, their preparation and Compositions containing them. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB35033/68A Expired GB1154290A (en) | 1965-07-07 | 1966-07-04 | Imidazole Derivatives, their preparation and compositions containing them |
Country Status (18)
| Country | Link |
|---|---|
| JP (3) | JPS5010865B1 (en) |
| AT (5) | AT294487B (en) |
| BE (1) | BE683796A (en) |
| BR (1) | BR6681050D0 (en) |
| CH (3) | CH565769A5 (en) |
| CY (1) | CY565A (en) |
| DE (1) | DE1620018B2 (en) |
| DK (1) | DK141287B (en) |
| ES (1) | ES329085A1 (en) |
| FI (1) | FI46961C (en) |
| FR (2) | FR1502699A (en) |
| GB (5) | GB1155529A (en) |
| IL (2) | IL25931A (en) |
| IT (1) | IT1061026B (en) |
| MY (1) | MY7100055A (en) |
| NL (1) | NL149793B (en) |
| NO (1) | NO122186B (en) |
| SE (1) | SE343578B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1280355A (en) * | 1969-06-20 | 1972-07-05 | Rech S Et D Applic Scient Et M | Substituted 5-nitro-imidazoles and their preparation |
| BE758145A (en) * | 1969-10-29 | 1971-04-28 | Smith Kline French Lab | ISO-THIO-UREES AND DERIVATIVES |
| US3678066A (en) * | 1970-03-06 | 1972-07-18 | Squibb & Sons Inc | Thiocyanic acid esters |
| US3968228A (en) * | 1973-11-13 | 1976-07-06 | Merck & Co., Inc. | 4-Nitro-5-cyanoimidazoles as coccidiostats |
| JPH02254965A (en) * | 1989-03-28 | 1990-10-15 | Chiyoudendou Hatsuden Kanren Kiki Zairyo Gijutsu Kenkyu Kumiai | Rotor for superconducting rotary electric machine |
| BR112017021183A2 (en) | 2015-04-02 | 2018-07-03 | Bayer Cropscience Ag | new 5-substituted imidazolylmethyl derivatives |
| CN109982999A (en) | 2016-09-29 | 2019-07-05 | 拜耳作物科学股份公司 | The imidazolyl methyl-derivatives that new 5- replaces |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5149436B2 (en) * | 1971-11-15 | 1976-12-27 |
-
1966
- 1966-06-08 IL IL25931A patent/IL25931A/en unknown
- 1966-07-04 GB GB35039/68A patent/GB1155529A/en not_active Expired
- 1966-07-04 GB GB32952/68A patent/GB1155528A/en not_active Expired
- 1966-07-04 GB GB29846/66A patent/GB1153347A/en not_active Expired
- 1966-07-04 GB GB38884/68A patent/GB1155530A/en not_active Expired
- 1966-07-04 GB GB35033/68A patent/GB1154290A/en not_active Expired
- 1966-07-05 AT AT545669A patent/AT294487B/en not_active IP Right Cessation
- 1966-07-05 AT AT643566A patent/AT284114B/en not_active IP Right Cessation
- 1966-07-05 ES ES0329085A patent/ES329085A1/en not_active Expired
- 1966-07-05 AT AT551669A patent/AT291988B/en not_active IP Right Cessation
- 1966-07-05 AT AT559369A patent/AT291990B/en not_active IP Right Cessation
- 1966-07-05 AT AT559269A patent/AT291989B/en not_active IP Right Cessation
- 1966-07-05 IT IT6615338A patent/IT1061026B/en active
- 1966-07-06 BR BR181050/66A patent/BR6681050D0/en unknown
- 1966-07-06 SE SE9274/66A patent/SE343578B/xx unknown
- 1966-07-06 FR FR68482A patent/FR1502699A/en not_active Expired
- 1966-07-06 NO NO163800A patent/NO122186B/no unknown
- 1966-07-06 DE DE1966M0070135 patent/DE1620018B2/en active Granted
- 1966-07-06 DK DK348866AA patent/DK141287B/en unknown
- 1966-07-06 FI FI661807A patent/FI46961C/en active
- 1966-07-07 JP JP41043868A patent/JPS5010865B1/ja active Pending
- 1966-07-07 BE BE683796D patent/BE683796A/xx not_active IP Right Cessation
- 1966-07-07 CH CH991771A patent/CH565769A5/xx not_active IP Right Cessation
- 1966-07-07 NL NL666609552A patent/NL149793B/en not_active IP Right Cessation
- 1966-07-07 CH CH988566A patent/CH522651A/en not_active IP Right Cessation
- 1966-07-07 CH CH988566A patent/CH562806A5/xx not_active IP Right Cessation
- 1966-10-05 FR FR78932A patent/FR5890M/fr not_active Expired
-
1970
- 1970-11-09 JP JP45097971A patent/JPS4843909B1/ja active Pending
- 1970-11-09 CY CY56570A patent/CY565A/en unknown
- 1970-11-27 IL IL35748A patent/IL35748A0/en unknown
-
1971
- 1971-12-31 MY MY197155A patent/MY7100055A/en unknown
-
1974
- 1974-11-29 JP JP49136394A patent/JPS5138718B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GB1154290A (en) | 1969-06-04 |
| FI46961B (en) | 1973-05-02 |
| BR6681050D0 (en) | 1973-05-15 |
| NL6609552A (en) | 1967-01-09 |
| CH562806A5 (en) | 1975-06-13 |
| GB1153347A (en) | 1969-05-29 |
| JPS4843909B1 (en) | 1973-12-21 |
| IL25931A (en) | 1972-01-27 |
| DE1620018A1 (en) | 1970-03-05 |
| CY565A (en) | 1970-11-09 |
| CH565769A5 (en) | 1975-08-29 |
| SE343578B (en) | 1972-03-13 |
| DE1620018B2 (en) | 1976-04-15 |
| AT291990B (en) | 1971-08-10 |
| DK141287B (en) | 1980-02-18 |
| AT291988B (en) | 1971-08-10 |
| MY7100055A (en) | 1971-12-31 |
| BE683796A (en) | 1967-01-09 |
| DK141287C (en) | 1980-07-07 |
| JPS5010865B1 (en) | 1975-04-24 |
| IL35748A0 (en) | 1971-01-28 |
| ES329085A1 (en) | 1967-05-01 |
| FR1502699A (en) | 1967-11-24 |
| CH522651A (en) | 1972-05-15 |
| AT294487B (en) | 1971-11-25 |
| NO122186B (en) | 1971-06-01 |
| JPS5138718B1 (en) | 1976-10-23 |
| AT284114B (en) | 1970-09-10 |
| NL149793B (en) | 1976-06-15 |
| FR5890M (en) | 1968-03-18 |
| GB1155528A (en) | 1969-06-18 |
| FI46961C (en) | 1973-08-10 |
| IT1061026B (en) | 1982-10-20 |
| GB1155529A (en) | 1969-06-18 |
| AT291989B (en) | 1971-08-10 |
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