ES329085A1 - A procedure for preparing nitroimidazoles. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for preparing nitroimidazoles. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES329085A1 ES329085A1 ES0329085A ES329085A ES329085A1 ES 329085 A1 ES329085 A1 ES 329085A1 ES 0329085 A ES0329085 A ES 0329085A ES 329085 A ES329085 A ES 329085A ES 329085 A1 ES329085 A1 ES 329085A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- formula
- compound
- nitro
- alkanoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004957 nitroimidazoles Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- -1 phenylalkanoyloxy Chemical group 0.000 abstract 14
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000001589 carboacyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000004043 oxo group Chemical group O=* 0.000 abstract 2
- 125000004660 phenylalkylthio group Chemical group 0.000 abstract 2
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000005115 alkyl carbamoyl group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000001118 alkylidene group Chemical group 0.000 abstract 1
- 125000003435 aroyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000592 heterocycloalkyl group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002071 phenylalkoxy group Chemical group 0.000 abstract 1
- 125000003170 phenylsulfonyl group Chemical group C1(=CC=CC=C1)S(=O)(=O)* 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Devices For Checking Fares Or Tickets At Control Points (AREA)
Abstract
A process for preparing nitroimidazoles, and more especially a compound having the formula: ** (See formula) ** where A and M are oxygen and sulfur, and R1 'is R1 or hydroxyalkyl, and R1 is alkyl or substituted alkyl, wherein said substituent is oxo, alkenyl, alkanoyloxy, phenylalkanoyloxy, alkoxy, phenylalkoxy, carboxyl, carboalkoxy, carbophenylalkoxy, carbamoyl, alkylcarbamoyl, phenylalkylcarbaryl, phenylcarbamoyl, cyano, halo, alkylthio, phenylalkylthio, alkyl sulfinyl, phenylalkyl-sulfinyl, phenylsulphinyl, alkylsulfonyl, phenylalkyl-sulphonyl, phenylsulphonyl or dialkylamino, carbamoyloxy; R3 is hydrogen, alkyl, or substituted alkyl, wherein the alkyl substituents are halo, alkoxy, oxo, phenyloxo, carboalkoxy, carbophenylalkoxy, alkanoyloxy, phenylalkanoyloxy, alkylthio, phenylalkylthio, dialkyldithiocarbamoyl, diphenylalkyldithiocarbamoyl, diphenyldithiocarbamoyl, dialkylamino, diphenylalkylamino or heterocycloalkyl; alkylsulfonyl or phenylsulfonyl; phenyl, alkanoyl, phenylalkanoyl, aroyl, cyanoacetyl, alkenoyl, chlorosulfonyl or dichlorophosphoryl; is lower alkylene, lower alkenylene, lower phenylalkylene, or lower alkylidene; W is nitro, cyano, phenyl or hydrogen; and P is hydrogen or nitro, provided that one of the groups W and P is nitro, which comprises reacting a compound having the formula ** (See formula) ** with a compound that has the formula R3-N-C=M III where A, M, P, Q, R1 and R3 are as defined above, and where R1 is alanoyloxyalkyl, if it is desired to hydrolyze with a base to obtain the corresponding compound where R1 'is hydroxyalkyl in which the terms alkyl, alkanoyl, and Alkoxyl mentioned above, denote lower alkyl, lower alkanoyl, and lower alkoxy, each containing 1 to 5 carbon atoms. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47023965A | 1965-07-07 | 1965-07-07 | |
| US55093266A | 1966-05-18 | 1966-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES329085A1 true ES329085A1 (en) | 1967-05-01 |
Family
ID=27043018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0329085A Expired ES329085A1 (en) | 1965-07-07 | 1966-07-05 | A procedure for preparing nitroimidazoles. (Machine-translation by Google Translate, not legally binding) |
Country Status (18)
| Country | Link |
|---|---|
| JP (3) | JPS5010865B1 (en) |
| AT (5) | AT294487B (en) |
| BE (1) | BE683796A (en) |
| BR (1) | BR6681050D0 (en) |
| CH (3) | CH562806A5 (en) |
| CY (1) | CY565A (en) |
| DE (1) | DE1620018B2 (en) |
| DK (1) | DK141287B (en) |
| ES (1) | ES329085A1 (en) |
| FI (1) | FI46961C (en) |
| FR (2) | FR1502699A (en) |
| GB (5) | GB1154290A (en) |
| IL (2) | IL25931A (en) |
| IT (1) | IT1061026B (en) |
| MY (1) | MY7100055A (en) |
| NL (1) | NL149793B (en) |
| NO (1) | NO122186B (en) |
| SE (1) | SE343578B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1280355A (en) * | 1969-06-20 | 1972-07-05 | Rech S Et D Applic Scient Et M | Substituted 5-nitro-imidazoles and their preparation |
| BE758145A (en) * | 1969-10-29 | 1971-04-28 | Smith Kline French Lab | ISO-THIO-UREES AND DERIVATIVES |
| US3678066A (en) * | 1970-03-06 | 1972-07-18 | Squibb & Sons Inc | Thiocyanic acid esters |
| US3968228A (en) * | 1973-11-13 | 1976-07-06 | Merck & Co., Inc. | 4-Nitro-5-cyanoimidazoles as coccidiostats |
| JPH02254965A (en) * | 1989-03-28 | 1990-10-15 | Chiyoudendou Hatsuden Kanren Kiki Zairyo Gijutsu Kenkyu Kumiai | Rotor for superconducting rotary electric machine |
| EA201792151A1 (en) * | 2015-04-02 | 2018-04-30 | Байер Кропсайенс Акциенгезельшафт | NEW 5-SUBSTITUTED IMIDAZOLE DERIVATIVES |
| CR20190165A (en) | 2016-09-29 | 2019-07-09 | Bayer Ag | Novel 5-substituted imidazolylmethyl derivatives |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5149436B2 (en) * | 1971-11-15 | 1976-12-27 |
-
1966
- 1966-06-08 IL IL25931A patent/IL25931A/en unknown
- 1966-07-04 GB GB35033/68A patent/GB1154290A/en not_active Expired
- 1966-07-04 GB GB35039/68A patent/GB1155529A/en not_active Expired
- 1966-07-04 GB GB38884/68A patent/GB1155530A/en not_active Expired
- 1966-07-04 GB GB29846/66A patent/GB1153347A/en not_active Expired
- 1966-07-04 GB GB32952/68A patent/GB1155528A/en not_active Expired
- 1966-07-05 AT AT545669A patent/AT294487B/en not_active IP Right Cessation
- 1966-07-05 ES ES0329085A patent/ES329085A1/en not_active Expired
- 1966-07-05 AT AT643566A patent/AT284114B/en not_active IP Right Cessation
- 1966-07-05 AT AT551669A patent/AT291988B/en not_active IP Right Cessation
- 1966-07-05 AT AT559369A patent/AT291990B/en not_active IP Right Cessation
- 1966-07-05 AT AT559269A patent/AT291989B/en not_active IP Right Cessation
- 1966-07-05 IT IT6615338A patent/IT1061026B/en active
- 1966-07-06 SE SE9274/66A patent/SE343578B/xx unknown
- 1966-07-06 FR FR68482A patent/FR1502699A/en not_active Expired
- 1966-07-06 NO NO163800A patent/NO122186B/no unknown
- 1966-07-06 DK DK348866AA patent/DK141287B/en unknown
- 1966-07-06 DE DE1966M0070135 patent/DE1620018B2/en active Granted
- 1966-07-06 FI FI661807A patent/FI46961C/en active
- 1966-07-06 BR BR181050/66A patent/BR6681050D0/en unknown
- 1966-07-07 JP JP41043868A patent/JPS5010865B1/ja active Pending
- 1966-07-07 NL NL666609552A patent/NL149793B/en not_active IP Right Cessation
- 1966-07-07 CH CH988566A patent/CH562806A5/xx not_active IP Right Cessation
- 1966-07-07 CH CH988566A patent/CH522651A/en not_active IP Right Cessation
- 1966-07-07 CH CH991771A patent/CH565769A5/xx not_active IP Right Cessation
- 1966-07-07 BE BE683796D patent/BE683796A/xx not_active IP Right Cessation
- 1966-10-05 FR FR78932A patent/FR5890M/fr not_active Expired
-
1970
- 1970-11-09 JP JP45097971A patent/JPS4843909B1/ja active Pending
- 1970-11-09 CY CY56570A patent/CY565A/en unknown
- 1970-11-27 IL IL35748A patent/IL35748A0/en unknown
-
1971
- 1971-12-31 MY MY197155A patent/MY7100055A/en unknown
-
1974
- 1974-11-29 JP JP49136394A patent/JPS5138718B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AT294487B (en) | 1971-11-25 |
| NL6609552A (en) | 1967-01-09 |
| NO122186B (en) | 1971-06-01 |
| FR1502699A (en) | 1967-11-24 |
| CY565A (en) | 1970-11-09 |
| FI46961C (en) | 1973-08-10 |
| MY7100055A (en) | 1971-12-31 |
| CH565769A5 (en) | 1975-08-29 |
| DK141287B (en) | 1980-02-18 |
| GB1155529A (en) | 1969-06-18 |
| GB1155530A (en) | 1969-06-18 |
| NL149793B (en) | 1976-06-15 |
| GB1154290A (en) | 1969-06-04 |
| DE1620018A1 (en) | 1970-03-05 |
| FR5890M (en) | 1968-03-18 |
| DE1620018B2 (en) | 1976-04-15 |
| GB1155528A (en) | 1969-06-18 |
| CH562806A5 (en) | 1975-06-13 |
| IT1061026B (en) | 1982-10-20 |
| AT291990B (en) | 1971-08-10 |
| AT291989B (en) | 1971-08-10 |
| FI46961B (en) | 1973-05-02 |
| IL25931A (en) | 1972-01-27 |
| AT284114B (en) | 1970-09-10 |
| BE683796A (en) | 1967-01-09 |
| CH522651A (en) | 1972-05-15 |
| JPS5010865B1 (en) | 1975-04-24 |
| GB1153347A (en) | 1969-05-29 |
| JPS5138718B1 (en) | 1976-10-23 |
| BR6681050D0 (en) | 1973-05-15 |
| JPS4843909B1 (en) | 1973-12-21 |
| SE343578B (en) | 1972-03-13 |
| DK141287C (en) | 1980-07-07 |
| AT291988B (en) | 1971-08-10 |
| IL35748A0 (en) | 1971-01-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES308421A1 (en) | Procedure for preparation of pesticide compounds. (Machine-translation by Google Translate, not legally binding) | |
| GB1048888A (en) | Cyanine dyestuffs | |
| ES394541A1 (en) | 1,2,3,4-tetrahydroisoquinoline-2-(thio)-carboxamides | |
| MX174156B (en) | DERIVATIVES OF -ARYL-4- (4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN-2 (3H) -IL) -BENZENE ACETONITRILE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | |
| ES329085A1 (en) | A procedure for preparing nitroimidazoles. (Machine-translation by Google Translate, not legally binding) | |
| ES329174A1 (en) | Procedure for preparing nitroimidazoles. (Machine-translation by Google Translate, not legally binding) | |
| ES458557A1 (en) | Quinazoline derivatives | |
| GB1292736A (en) | C2c 17x-190-277 1e4k3 1e4k4 1e4k6 1q11g 1q11j 1q4 0q6c 1q8a 1q9f1 200 215 220 227 22y 246 250 253 25y 305 30y 315 31y 326 332 364 36y 373 37y 3a13c10d 3a13c10h 3a13c3b 3a13c4c 3a13c5 3a13c6b 500 50y 603 621 624 661 662 666 669 791 79y ja mb mk mm qn | |
| ES391492A1 (en) | Ureidophenylisothioureas | |
| ES315823A1 (en) | Procedure for the preparation of insecticides compositions. (Machine-translation by Google Translate, not legally binding) | |
| ES312240A1 (en) | A process to produce a 5- (aryloxymethyl) -2-oxazolidinationa. (Machine-translation by Google Translate, not legally binding) | |
| ES443201A1 (en) | PROCEDURE FOR PREPARING DERIVATIVES OF 5-NITROIMIDAZOLE. | |
| ES332749A1 (en) | PROCEDURE FOR THE PRODUCTION OF DERIVATIVES OF SULFONIL UREA. | |
| GB1090283A (en) | (2-aminoethyl)-hydroquinones | |
| ES327573A1 (en) | Procedure for obtaining a hervicid mixture. (Machine-translation by Google Translate, not legally binding) | |
| ES330768A1 (en) | Method of obtaining herbicidal compounds. (Machine-translation by Google Translate, not legally binding) | |
| ES2036600T3 (en) | PROCEDURE FOR PREPARING 1- (3- (2-DIALQUILAMINOETOXI) -2-TIENIL) -3-FENIL-1-PROPANONAS. | |
| GB1317598A (en) | Pesticidal adducts of thiophosphorus acids and n-vinyl compounds and process of preparing same | |
| ES324458A1 (en) | A procedure for the preparation of benzodiazepine derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES315014A1 (en) | Procedures for the preparation of an amidine or a corresponding acid addition salt. (Machine-translation by Google Translate, not legally binding) | |
| ES340047A1 (en) | PROCEDURE FOR THE PRODUCTION OF SULPHONILIC UREA DERIVATIVES. | |
| GB1097277A (en) | Improvements in or relating to organic sulfamoyl compounds | |
| ES426662A1 (en) | Reserpine derivatives | |
| ES316695A1 (en) | Procedure for preparation of finelcarbamoil-3 oxadiazol1,3,4 onas-2, of fungicide effects. (Machine-translation by Google Translate, not legally binding) | |
| ES284995A1 (en) | Improvements introduced in the preparation of biocidal compounds (Machine-translation by Google Translate, not legally binding) |