GB1122202A - New derivatives of phenylacetic acid and their preparation - Google Patents
New derivatives of phenylacetic acid and their preparationInfo
- Publication number
- GB1122202A GB1122202A GB3787/66A GB378766A GB1122202A GB 1122202 A GB1122202 A GB 1122202A GB 3787/66 A GB3787/66 A GB 3787/66A GB 378766 A GB378766 A GB 378766A GB 1122202 A GB1122202 A GB 1122202A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenylacetic acid
- formula
- give
- acids
- bcooh
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical class OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 5
- 150000007513 acids Chemical class 0.000 abstract 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002825 nitriles Chemical class 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- YSJHDWWFQVLNMR-UHFFFAOYSA-N 2-(2-benzylphenyl)acetic acid Chemical class OC(=O)CC1=CC=CC=C1CC1=CC=CC=C1 YSJHDWWFQVLNMR-UHFFFAOYSA-N 0.000 abstract 1
- RUBZFONQFHZKOR-UHFFFAOYSA-N 2-[2-[(4-bromophenyl)methyl]phenyl]acetic acid Chemical compound BrC1=CC=C(CC2=C(C=CC=C2)CC(=O)O)C=C1 RUBZFONQFHZKOR-UHFFFAOYSA-N 0.000 abstract 1
- KDBMZNGITZUAOS-UHFFFAOYSA-N 2-[2-[(4-chlorophenyl)methyl]phenyl]acetic acid Chemical compound ClC1=CC=C(CC2=C(C=CC=C2)CC(=O)O)C=C1 KDBMZNGITZUAOS-UHFFFAOYSA-N 0.000 abstract 1
- YLNLIBIXDVZUOR-UHFFFAOYSA-N 2-[2-[(4-methoxyphenyl)methyl]phenyl]acetic acid Chemical compound C1=CC(OC)=CC=C1CC1=CC=CC=C1CC(O)=O YLNLIBIXDVZUOR-UHFFFAOYSA-N 0.000 abstract 1
- NGIZGRYVQRJRST-UHFFFAOYSA-N 2-[2-[(4-methylphenyl)methyl]phenyl]acetic acid Chemical compound C1=CC(C)=CC=C1CC1=CC=CC=C1CC(O)=O NGIZGRYVQRJRST-UHFFFAOYSA-N 0.000 abstract 1
- QDTSZYYETVNSNV-UHFFFAOYSA-N 2-[2-[(4-methylsulfanylphenyl)methyl]phenyl]acetic acid Chemical compound CSC1=CC=C(CC2=C(C=CC=C2)CC(=O)O)C=C1 QDTSZYYETVNSNV-UHFFFAOYSA-N 0.000 abstract 1
- GVFFCJQLWBFFOK-UHFFFAOYSA-N 2-[2-[[4-(trifluoromethyl)phenyl]methyl]phenyl]acetic acid Chemical compound OC(=O)CC1=C(CC2=CC=C(C=C2)C(F)(F)F)C=CC=C1 GVFFCJQLWBFFOK-UHFFFAOYSA-N 0.000 abstract 1
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 238000005727 Friedel-Crafts reaction Methods 0.000 abstract 1
- LGRFSURHDFAFJT-UHFFFAOYSA-N Phthalic anhydride Natural products C1=CC=C2C(=O)OC(=O)C2=C1 LGRFSURHDFAFJT-UHFFFAOYSA-N 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal cyanide Chemical class 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- JHIWVOJDXOSYLW-UHFFFAOYSA-N butyl 2,2-difluorocyclopropane-1-carboxylate Chemical compound CCCCOC(=O)C1CC1(F)F JHIWVOJDXOSYLW-UHFFFAOYSA-N 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000004702 methyl esters Chemical class 0.000 abstract 1
- 235000011118 potassium hydroxide Nutrition 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/68—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
- C07C63/72—Polycyclic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR3484A FR1466245A (fr) | 1965-01-27 | 1965-01-27 | Nouveaux dérivés de l'acide benzyl-2 phénylacétique et leur préparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1122202A true GB1122202A (en) | 1968-07-31 |
Family
ID=8569373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3787/66A Expired GB1122202A (en) | 1965-01-27 | 1966-01-27 | New derivatives of phenylacetic acid and their preparation |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE675608A (enrdf_load_stackoverflow) |
| CH (1) | CH441266A (enrdf_load_stackoverflow) |
| FR (2) | FR1466245A (enrdf_load_stackoverflow) |
| GB (1) | GB1122202A (enrdf_load_stackoverflow) |
| LU (1) | LU50326A1 (enrdf_load_stackoverflow) |
| NL (1) | NL6600710A (enrdf_load_stackoverflow) |
| SE (1) | SE305213B (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3040994A1 (de) | 1980-10-31 | 1982-06-09 | Henkel KGaA, 4000 Düsseldorf | Verfahren zur herstellung von 13-oxabicyclo 10.3.0 -pentadecan |
-
1965
- 1965-01-27 FR FR3484A patent/FR1466245A/fr not_active Expired
- 1965-04-16 FR FR13633A patent/FR4395M/fr not_active Expired
-
1966
- 1966-01-19 NL NL6600710A patent/NL6600710A/xx unknown
- 1966-01-24 SE SE89466A patent/SE305213B/xx unknown
- 1966-01-26 LU LU50326A patent/LU50326A1/xx unknown
- 1966-01-26 BE BE675608D patent/BE675608A/xx unknown
- 1966-01-27 CH CH111066A patent/CH441266A/fr unknown
- 1966-01-27 GB GB3787/66A patent/GB1122202A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR4395M (enrdf_load_stackoverflow) | 1966-09-05 |
| CH441266A (fr) | 1967-08-15 |
| BE675608A (enrdf_load_stackoverflow) | 1966-07-26 |
| SE305213B (enrdf_load_stackoverflow) | 1968-10-21 |
| FR1466245A (fr) | 1967-01-20 |
| LU50326A1 (enrdf_load_stackoverflow) | 1966-03-28 |
| NL6600710A (enrdf_load_stackoverflow) | 1966-07-28 |
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