GB744961A - Unsaturated nitro thiophene derivatives - Google Patents

Unsaturated nitro thiophene derivatives

Info

Publication number
GB744961A
GB744961A GB3035953A GB3035953A GB744961A GB 744961 A GB744961 A GB 744961A GB 3035953 A GB3035953 A GB 3035953A GB 3035953 A GB3035953 A GB 3035953A GB 744961 A GB744961 A GB 744961A
Authority
GB
United Kingdom
Prior art keywords
nitro
give
thienyl
acrolein
acetic anhydride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3035953A
Inventor
Gino Carrara
Renato Ettorre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit SpA filed Critical Lepetit SpA
Priority to GB3035953A priority Critical patent/GB744961A/en
Publication of GB744961A publication Critical patent/GB744961A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/42—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms with nitro or nitroso radicals directly attached to ring carbon atoms
    • C07D333/44—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms with nitro or nitroso radicals directly attached to ring carbon atoms attached in position 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

The invention comprises compounds of the formula <FORM:0744961/IV(a)/1> wherein R is hydrogen or halogen, Z is a hydroxy group or a lower aliphatic alkoxy group of 1 to 8 carbon atoms or an amino group, or R and Z are both hydrogen, also a compound of the formula <FORM:0744961/IV(a)/2> The above acids in which Z is a hydroxy group may be made by oxidizing the corresponding aldehydes and may in turn be converted into the esters or amides. In examples (1) acetaldehyde is added to 5-nitro-2-thiophenealdehyde alcoholic potassium hydroxide is added followed by an excess of acetic anhydride and the mixture is heated to give 5-nitro-2-thienyl acrolein, reaction of this with acetic anhydride in the presence of sulphuric acid gives 5-nitro-2-thienyl acrolein diacetate of the formula given above; (2) 5-nitro-2-thiophenealdehyde is reacted with sodium acetate and acetic anhydride to give 5-nitro-2-thiopheneacrylic acid which is esterified to give the ethyl ester or treated with phosphorus pentachloride followed by ammonia to give the amide, and (3) a -bromo - b - (5 - nitro - 2 - thenyl) - acrolein is oxidized with chromium trioxide to a -bromo-b -(5-nitro-2-thienyl) acrylic acid which is converted into the corresponding ethyl ester and amide.
GB3035953A 1953-11-03 1953-11-03 Unsaturated nitro thiophene derivatives Expired GB744961A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3035953A GB744961A (en) 1953-11-03 1953-11-03 Unsaturated nitro thiophene derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3035953A GB744961A (en) 1953-11-03 1953-11-03 Unsaturated nitro thiophene derivatives

Publications (1)

Publication Number Publication Date
GB744961A true GB744961A (en) 1956-02-15

Family

ID=10306409

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3035953A Expired GB744961A (en) 1953-11-03 1953-11-03 Unsaturated nitro thiophene derivatives

Country Status (1)

Country Link
GB (1) GB744961A (en)

Similar Documents

Publication Publication Date Title
SE7606170L (en) PROCEDURE FOR MANUFACTURE OF MALONIC ACID RADIAL COOLERS
GB1283225A (en) Derivatives of cyclopropane carboxylic acid and process for their preparation
GB1042631A (en) New fused polycyclic hydrocarbon derivatives and processes for the preparation thereof
GB744961A (en) Unsaturated nitro thiophene derivatives
ES8106708A1 (en) Process for producing 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone and its intermediates
GB1095882A (en) Substituted isochromans
GB934017A (en) Color formers for producing yellow dye images by color development
ES421713A1 (en) Pregnane acid derivatives
US2259895A (en) Process for manufacture of aliphatic carboxylic acid anhydrides
JPS5762295A (en) Manufacture of 17alpha-hydroxy- and 17a alpha-hydroxy-d-homo-etiocarboxylic acid
FR2246538A1 (en) N,N-Dialkylamides of unsaturated aliphatic acids - obtd. by forming mixed anhydride using catalyst, and reacting with amine
ES405648A1 (en) Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding)
GB1209799A (en) Aminoalkylbicyclocarboxylic acids
GB1031748A (en) 16-substituted androstanes
GB951670A (en) Process for the preparation of tetraesters of penta-erythritol
ES437285A1 (en) Polycarboxylic acids salts and esters their preparation and uses
GB1017979A (en) Improvements in or relating to the preparation of chloro-acetoacetamides and to substituted dioxolan derivatives of acetic acid esters as intermediates in said preparation
GB1419910A (en) Synthesis of itaconic acid from 2,4,4-substituted-2-oxazolines and intermediates thereof
GB940140A (en) Improvements in or relating to a process for the preparation of ยช -cyclopropane acrylic acids or derivatives thereof
GB614772A (en) The manufacture of esters of pyridyl-3-carbinol
GB615908A (en) Manufacture of furane derivatives
GB674710A (en) A method of preparing aliphatic acyl hydroxypolycarboxylic acid anhydrides
GB579715A (en) Improvements in or relating to the manufacture of vinyl and ethylidene esters
GB1382469A (en) Cyclohexanepentol derivatives and process for preparing the same
GB830671A (en) Process for oxidizing glutaraldehydes