GB1089071A - Indole derivatives - Google Patents

Indole derivatives

Info

Publication number
GB1089071A
GB1089071A GB5366/65A GB536665A GB1089071A GB 1089071 A GB1089071 A GB 1089071A GB 5366/65 A GB5366/65 A GB 5366/65A GB 536665 A GB536665 A GB 536665A GB 1089071 A GB1089071 A GB 1089071A
Authority
GB
United Kingdom
Prior art keywords
alkyl
amino
alkoxy
hydroxy
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5366/65A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1089071A publication Critical patent/GB1089071A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
GB5366/65A 1964-02-28 1965-02-08 Indole derivatives Expired GB1089071A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34830264A 1964-02-28 1964-02-28
US523291A US3351630A (en) 1964-02-28 1966-01-27 Alpha-substituted-3-indolyl acetic acid compounds and processes for their preparation

Publications (1)

Publication Number Publication Date
GB1089071A true GB1089071A (en) 1967-11-01

Family

ID=26995638

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5366/65A Expired GB1089071A (en) 1964-02-28 1965-02-08 Indole derivatives

Country Status (6)

Country Link
US (1) US3351630A (https=)
BR (1) BR6567558D0 (https=)
DE (1) DE1595924A1 (https=)
FR (1) FR1460528A (https=)
GB (1) GB1089071A (https=)
NL (1) NL6502481A (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3390154A (en) * 1966-09-09 1968-06-25 Merck & Co Inc Process for preparing 3-indolyl acetic acids
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
US4690943A (en) * 1984-09-19 1987-09-01 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds
BR9501404A (pt) 1994-04-01 1996-03-05 Lilly Co Eli 1H-indol-3 glioxilamida e formulação farmacèutica
US5641800A (en) * 1994-07-21 1997-06-24 Eli Lilly And Company 1H-indole-1-functional sPLA2 inhibitors
DE19636150A1 (de) * 1996-09-06 1998-03-12 Asta Medica Ag N-substituierte Indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender Wirkung
DE19814838C2 (de) * 1998-04-02 2001-01-18 Asta Medica Ag Indolyl-3-glyoxylsäure-Derivate mit Antitumorwirkung
CZ302588B6 (cs) * 1998-04-02 2011-07-27 Ziopharm Oncology, Inc. Použití N-substituovaného indol-3-glyoxylamidu pro výrobu léciva
US6380397B1 (en) * 1999-04-15 2002-04-30 Eli Lilly And Company Process for preparing 4-substituted-1H-indole-3-glyoxamides
US6903104B2 (en) 2001-12-06 2005-06-07 National Health Research Institutes Indol-3-YL-2-oxoacetamide compounds and methods of use thereof
US7632955B2 (en) * 2001-12-13 2009-12-15 National Health Research Institutes Indole compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE621313A (https=) *
US2825734A (en) * 1955-04-11 1958-03-04 Upjohn Co Reduction of carbonylic radicals in indolyl-3 compounds
US3038002A (en) * 1957-08-19 1962-06-05 Fundamental Res Inc Syntheses of alpha-methoxyphenylacetates
US3078214A (en) * 1958-09-12 1963-02-19 Sandoz Ag Treatment of mental disturbances with esters of indoles
BE615395A (https=) * 1962-03-21

Also Published As

Publication number Publication date
DE1595924A1 (de) 1970-02-12
BR6567558D0 (pt) 1973-08-02
FR1460528A (fr) 1966-12-02
NL6502481A (https=) 1965-08-30
US3351630A (en) 1967-11-07

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