GB1080765A - Pregnane-3-thioketals - Google Patents
Pregnane-3-thioketalsInfo
- Publication number
- GB1080765A GB1080765A GB7943/65A GB794365A GB1080765A GB 1080765 A GB1080765 A GB 1080765A GB 7943/65 A GB7943/65 A GB 7943/65A GB 794365 A GB794365 A GB 794365A GB 1080765 A GB1080765 A GB 1080765A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- group
- oxido
- hydroxy
- followed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- -1 ethylene, 1,2-propylene Chemical group 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- 239000007868 Raney catalyst Substances 0.000 abstract 1
- NPXOKRUENSOPAO-UHFFFAOYSA-N Raney nickel Chemical compound [Al].[Ni] NPXOKRUENSOPAO-UHFFFAOYSA-N 0.000 abstract 1
- 229910000564 Raney nickel Inorganic materials 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000005695 dehalogenation reaction Methods 0.000 abstract 1
- 150000004662 dithiols Chemical class 0.000 abstract 1
- 238000006735 epoxidation reaction Methods 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052740 iodine Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229960003387 progesterone Drugs 0.000 abstract 1
- 239000000186 progesterone Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US351515A US3192202A (en) | 1964-03-12 | 1964-03-12 | 3-thioketals of pregnadiene and method of preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1080765A true GB1080765A (en) | 1967-08-23 |
Family
ID=23381245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7943/65A Expired GB1080765A (en) | 1964-03-12 | 1965-02-24 | Pregnane-3-thioketals |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3192202A (enExample) |
| BE (1) | BE661067A (enExample) |
| BR (1) | BR6567748D0 (enExample) |
| CH (1) | CH461479A (enExample) |
| DE (1) | DE1593191A1 (enExample) |
| GB (1) | GB1080765A (enExample) |
| NL (1) | NL6503218A (enExample) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2887478A (en) * | 1952-11-12 | 1959-05-19 | Pfizer & Co C | 20-steroid-tertiary carbinols and the preparation of 17-keto steroids therefrom |
| US2789989A (en) * | 1953-05-13 | 1957-04-23 | Glidden Co | Preparation of 21-halo steroids |
| US2773868A (en) * | 1954-05-10 | 1956-12-11 | Pfizer & Co C | Steroid ketal |
| US2744108A (en) * | 1955-01-13 | 1956-05-01 | Searle & Co | 3-ethylene mercaptoles of 11-oxygenated derivatives of 17, 21-dihydroxy-4-pregnene-3, 20-diones |
-
0
- BE BE661067D patent/BE661067A/xx unknown
-
1964
- 1964-03-12 US US351515A patent/US3192202A/en not_active Expired - Lifetime
-
1965
- 1965-02-24 GB GB7943/65A patent/GB1080765A/en not_active Expired
- 1965-03-10 CH CH329265A patent/CH461479A/de unknown
- 1965-03-11 BR BR167748/65A patent/BR6567748D0/pt unknown
- 1965-03-11 DE DE19651593191 patent/DE1593191A1/de active Pending
- 1965-03-12 NL NL6503218A patent/NL6503218A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL6503218A (enExample) | 1965-09-13 |
| CH461479A (de) | 1968-08-31 |
| US3192202A (en) | 1965-06-29 |
| DE1593191A1 (de) | 1969-09-11 |
| BR6567748D0 (pt) | 1973-08-02 |
| BE661067A (enExample) |
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