GB1048907A - Penicillins - Google Patents

Penicillins

Info

Publication number
GB1048907A
GB1048907A GB3009464A GB3009464A GB1048907A GB 1048907 A GB1048907 A GB 1048907A GB 3009464 A GB3009464 A GB 3009464A GB 3009464 A GB3009464 A GB 3009464A GB 1048907 A GB1048907 A GB 1048907A
Authority
GB
United Kingdom
Prior art keywords
penicillins
acid
salt
formula
penicillin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3009464A
Inventor
Edward Raymond Stove
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority to GB3009464A priority Critical patent/GB1048907A/en
Publication of GB1048907A publication Critical patent/GB1048907A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Abstract

Penicillins of formula <FORM:1048907/C2/1> where R is H or an alkyl, aralkyl, aryl or heterocyclic group which may be substituted, are produced by treating 6-aminopenicillanic acid or a salt thereof with a formamido acid of formula <FORM:1048907/C2/2> wherein R has the above meaning, or a functional derivative thereof, e.g. acid chloride. Alternatively, the corresponding a -aminopenicillin may be treated with a mild formylating agent such as formyl fluoride or formic anhydride. A typical penicillin is a -formamidobenzyl penicillin. The penicillins may be converted to their non-toxic salts, e.g. sodium, calcium, aluminium and amine salts, e.g. dehydro-abietylamine salt.
GB3009464A 1964-07-29 1964-07-29 Penicillins Expired GB1048907A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3009464A GB1048907A (en) 1964-07-29 1964-07-29 Penicillins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3009464A GB1048907A (en) 1964-07-29 1964-07-29 Penicillins

Publications (1)

Publication Number Publication Date
GB1048907A true GB1048907A (en) 1966-11-23

Family

ID=10302182

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3009464A Expired GB1048907A (en) 1964-07-29 1964-07-29 Penicillins

Country Status (1)

Country Link
GB (1) GB1048907A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329285A (en) 1979-12-27 1982-05-11 C R A F Sud Formyl derivatives of hydrazinopenicillins

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329285A (en) 1979-12-27 1982-05-11 C R A F Sud Formyl derivatives of hydrazinopenicillins
EP0031951B1 (en) * 1979-12-27 1984-07-25 CRAF Sud Formyl derivatives of hydrazinomethylpenicillins, process for their preparation and pharmaceutical compositions containing these compounds

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