GB1037643A - Improvements in or relating to benzofuran derivatives - Google Patents

Improvements in or relating to benzofuran derivatives

Info

Publication number
GB1037643A
GB1037643A GB13001/63A GB1300163A GB1037643A GB 1037643 A GB1037643 A GB 1037643A GB 13001/63 A GB13001/63 A GB 13001/63A GB 1300163 A GB1300163 A GB 1300163A GB 1037643 A GB1037643 A GB 1037643A
Authority
GB
United Kingdom
Prior art keywords
radical
halogen
hydrogen
compound
give
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB13001/63A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of GB1037643A publication Critical patent/GB1037643A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Novel benzofuran derivatives of general formula I <FORM:1037643/C2/1> and esters thereof, wherein R2 is a straight' branched or cyclic alkyl or alkenyl radical of up to 5 carbon atoms or a phenyl radical optionally substituted by halogen or alkoxy, R5 is hydrogen, a straight or branched alkyl or alkenyl radical of up to 5 carbon atoms, a phenyl radical optionally substituted by halogen or nitro, a phenacyl radical or a substituted or unsubstituted benzyl radical, are prepared by reacting p-quinone with a b -keto-acid ethyl ester of the general formula R2-CO-CH2-COOC2H5 to give a compound of the above formula wherein R5 is hydrogen and optionally further reacting this compound with a compound of formula R6-Halogen wherein R6 has the same significance as R5 with the exception of hydrogen, and optionally saponifying the resulting ester to give the free acid.
GB13001/63A 1962-04-13 1963-04-02 Improvements in or relating to benzofuran derivatives Expired GB1037643A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEB0066817 1962-04-13

Publications (1)

Publication Number Publication Date
GB1037643A true GB1037643A (en) 1966-08-03

Family

ID=6975282

Family Applications (1)

Application Number Title Priority Date Filing Date
GB13001/63A Expired GB1037643A (en) 1962-04-13 1963-04-02 Improvements in or relating to benzofuran derivatives

Country Status (2)

Country Link
AT (1) AT242126B (en)
GB (1) GB1037643A (en)

Also Published As

Publication number Publication date
AT242126B (en) 1965-08-25

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