ES334818A1 - Procedure for preparing substitute 1,3-benzoxacines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for preparing substitute 1,3-benzoxacines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES334818A1
ES334818A1 ES334818A ES334818A ES334818A1 ES 334818 A1 ES334818 A1 ES 334818A1 ES 334818 A ES334818 A ES 334818A ES 334818 A ES334818 A ES 334818A ES 334818 A1 ES334818 A1 ES 334818A1
Authority
ES
Spain
Prior art keywords
benzoxacines
translation
procedure
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES334818A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of ES334818A1 publication Critical patent/ES334818A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C07D265/08—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedure to prepare substituted 1,3-benzoxacines from the structure ** (See formula) ** where R and R1 may be the same or different and mean hydrogen, halogen, a cyano or nitro group or an optionally substituted alkyl or alkoxy radical of 1 to 4 carbon atoms, R 'and R "may be the same or different and mean hydrogen, phenyl or an alkyl radical of 1 to 4 carbon atoms, optionally substituted, while n is 1 or 2, characterized by reacting the hydroxyarylamino-alkylcarboxylic acid ester with phosgene and then reacting 3-carboalkoxy-alkyl-1,3-benzoxacin-2-one with ammonia to obtain 3-carboxanido-alkyl-1,3-benzoxacin-2- ona (Machine-translation by Google Translate, not legally binding)
ES334818A 1965-12-23 1966-12-22 Procedure for preparing substitute 1,3-benzoxacines. (Machine-translation by Google Translate, not legally binding) Expired ES334818A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1263865 1965-12-23
IT2238566 1966-09-14

Publications (1)

Publication Number Publication Date
ES334818A1 true ES334818A1 (en) 1968-03-01

Family

ID=26326577

Family Applications (1)

Application Number Title Priority Date Filing Date
ES334818A Expired ES334818A1 (en) 1965-12-23 1966-12-22 Procedure for preparing substitute 1,3-benzoxacines. (Machine-translation by Google Translate, not legally binding)

Country Status (7)

Country Link
AT (1) AT264535B (en)
BE (1) BE691641A (en)
ES (1) ES334818A1 (en)
FI (1) FI46729C (en)
IL (1) IL27092A (en)
NO (1) NO121044B (en)
SE (1) SE316773B (en)

Also Published As

Publication number Publication date
BE691641A (en) 1967-06-22
FI46729B (en) 1973-02-28
AT264535B (en) 1968-09-10
DE1620436A1 (en) 1970-05-21
NO121044B (en) 1971-01-11
IL27092A (en) 1970-11-30
FI46729C (en) 1973-06-11
SE316773B (en) 1969-11-03

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