GB1005879A - Basic phenothiazines and imino-dibenzyl derivatives - Google Patents

Basic phenothiazines and imino-dibenzyl derivatives

Info

Publication number
GB1005879A
GB1005879A GB33867/62A GB3386762A GB1005879A GB 1005879 A GB1005879 A GB 1005879A GB 33867/62 A GB33867/62 A GB 33867/62A GB 3386762 A GB3386762 A GB 3386762A GB 1005879 A GB1005879 A GB 1005879A
Authority
GB
United Kingdom
Prior art keywords
heptamethylene
imine
formula
prepared
heptamethyleneimine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB33867/62A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyesult Gyogyszer es Tapszergyar
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyesult Gyogyszer es Tapszergyar
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyesult Gyogyszer es Tapszergyar, Egyt Gyogyszervegyeszeti Gyar filed Critical Egyesult Gyogyszer es Tapszergyar
Publication of GB1005879A publication Critical patent/GB1005879A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
    • C07D279/26—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom without other substituents attached to the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
    • C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

The invention comprises compounds of the general formula <FORM:1005879/C2/1> and their acid addition and quaternary ammonium salts wherein X represents -S- or -CH2-CH2-, the groups A and B, which may be the same or different, represent hydrogen or halogen atoms or alkyl, aralkyl, alkoxy, aryloxy, or trifluoromethyl radicals and Z represents a bivalent straight or branched hydrocarbon chain and the preparation thereof by condensing a heterocyclic compound of the formula <FORM:1005879/C2/2> with an amine of the formula <FORM:1005879/C2/3> or a salt thereof wherein Y represents a reactive ester residue; or by reacting a heterocyclic compound of the formula <FORM:1005879/C2/4> with a heptamethyleneimine or where a quaternary ammonium salt is desired with an N-substituted heptamethyleneimine; or by heating to at least 100 DEG C. a compound of the general formula <FORM:1005879/C2/5> N - (3 - Chloropropyl) - heptamethylene - imine is prepared from 1-chloro-3-bromopropane and heptamethylene - imine. N - (2 - Chloroethyl) - heptamethylene imine hydrochloride is prepared from thionyl chloride and N-(2-hydroxyethyl)-heptamethylene-imine, in turn prepared from heptamethylene-imine and ethylene oxide.
GB33867/62A 1961-09-05 1962-09-04 Basic phenothiazines and imino-dibenzyl derivatives Expired GB1005879A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUGO000826 1961-09-05

Publications (1)

Publication Number Publication Date
GB1005879A true GB1005879A (en) 1965-09-29

Family

ID=10996633

Family Applications (1)

Application Number Title Priority Date Filing Date
GB33867/62A Expired GB1005879A (en) 1961-09-05 1962-09-04 Basic phenothiazines and imino-dibenzyl derivatives

Country Status (5)

Country Link
CH (1) CH425799A (en)
DE (1) DE1445687A1 (en)
FR (1) FR2523M (en)
GB (1) GB1005879A (en)
NL (2) NL122487C (en)

Also Published As

Publication number Publication date
CH425799A (en) 1966-12-15
NL282869A (en)
FR2523M (en) 1964-05-11
DE1445687A1 (en) 1969-01-09
NL122487C (en)

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