GB0911566D0 - T cell receptors - Google Patents

T cell receptors

Info

Publication number
GB0911566D0
GB0911566D0 GBGB0911566.8A GB0911566A GB0911566D0 GB 0911566 D0 GB0911566 D0 GB 0911566D0 GB 0911566 A GB0911566 A GB 0911566A GB 0911566 D0 GB0911566 D0 GB 0911566D0
Authority
GB
United Kingdom
Prior art keywords
cell receptors
receptors
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0911566.8A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunocore Ltd
Original Assignee
Immunocore Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunocore Ltd filed Critical Immunocore Ltd
Priority to GBGB0911566.8A priority Critical patent/GB0911566D0/en
Publication of GB0911566D0 publication Critical patent/GB0911566D0/en
Priority to JP2012518126A priority patent/JP5872464B2/ja
Priority to AU2010267758A priority patent/AU2010267758C1/en
Priority to PT107345241T priority patent/PT2448963E/pt
Priority to MX2012000155A priority patent/MX2012000155A/es
Priority to BR112012000107A priority patent/BR112012000107A2/pt
Priority to CN2010800351402A priority patent/CN102574906A/zh
Priority to ES10734524.1T priority patent/ES2498190T3/es
Priority to CN201710535038.2A priority patent/CN107266560A/zh
Priority to DK10734524.1T priority patent/DK2448963T3/da
Priority to PCT/GB2010/001277 priority patent/WO2011001152A1/en
Priority to CA2766505A priority patent/CA2766505C/en
Priority to CN201410257886.8A priority patent/CN104017067B/zh
Priority to HK12110227.0A priority patent/HK1169422B/en
Priority to EP10734524.1A priority patent/EP2448963B1/en
Priority to EA201270135A priority patent/EA026918B1/ru
Priority to ZA2011/09522A priority patent/ZA201109522B/en
Priority to US13/342,579 priority patent/US8519100B2/en
Priority to US13/947,580 priority patent/US9068178B2/en
Priority to JP2015196799A priority patent/JP6186412B2/ja
Priority to NL301193C priority patent/NL301193I2/nl
Priority to FIC20220037C priority patent/FIC20220037I1/fi
Priority to FR22C1046C priority patent/FR22C1046I2/fr
Priority to LU00278C priority patent/LUC00278I2/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053—Skin, nerves, brain
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GBGB0911566.8A 2009-07-03 2009-07-03 T cell receptors Ceased GB0911566D0 (en)

Priority Applications (24)

Application Number Priority Date Filing Date Title
GBGB0911566.8A GB0911566D0 (en) 2009-07-03 2009-07-03 T cell receptors
EA201270135A EA026918B1 (ru) 2009-07-03 2010-07-01 T-клеточные рецепторы
PCT/GB2010/001277 WO2011001152A1 (en) 2009-07-03 2010-07-01 T cell receptors
CN201410257886.8A CN104017067B (zh) 2009-07-03 2010-07-01 T细胞受体
PT107345241T PT2448963E (pt) 2009-07-03 2010-07-01 Recetores das células
MX2012000155A MX2012000155A (es) 2009-07-03 2010-07-01 Receptores de celulas t.
BR112012000107A BR112012000107A2 (pt) 2009-07-03 2010-07-01 receptores de células t.
CN2010800351402A CN102574906A (zh) 2009-07-03 2010-07-01 T细胞受体
ES10734524.1T ES2498190T3 (es) 2009-07-03 2010-07-01 Receptores de linfocitos T
CN201710535038.2A CN107266560A (zh) 2009-07-03 2010-07-01 T细胞受体
DK10734524.1T DK2448963T3 (da) 2009-07-03 2010-07-01 T-celle receptorer
JP2012518126A JP5872464B2 (ja) 2009-07-03 2010-07-01 Ｔ細胞レセプター
CA2766505A CA2766505C (en) 2009-07-03 2010-07-01 T cell receptors
AU2010267758A AU2010267758C1 (en) 2009-07-03 2010-07-01 T cell receptors
HK12110227.0A HK1169422B (en) 2009-07-03 2010-07-01 T cell receptors
EP10734524.1A EP2448963B1 (en) 2009-07-03 2010-07-01 T cell receptors
ZA2011/09522A ZA201109522B (en) 2009-07-03 2011-12-22 T cell receptors
US13/342,579 US8519100B2 (en) 2009-07-03 2012-01-03 Non-naturally occurring T cell receptors
US13/947,580 US9068178B2 (en) 2009-07-03 2013-07-22 Nucleic acid molecules encoding non-naturally occurring T cell receptors and cells thereof
JP2015196799A JP6186412B2 (ja) 2009-07-03 2015-10-02 Ｔ細胞レセプター
NL301193C NL301193I2 (nl) 2009-07-03 2022-08-15 tebentafusp
FIC20220037C FIC20220037I1 (fi) 2009-07-03 2022-08-31 Tebentafuspi
FR22C1046C FR22C1046I2 (fr) 2009-07-03 2022-09-02 Recepteurs des cellules t
LU00278C LUC00278I2 (enExample) 2009-07-03 2022-09-05

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0911566.8A GB0911566D0 (en) 2009-07-03 2009-07-03 T cell receptors

Publications (1)

Publication Number Publication Date
GB0911566D0 true GB0911566D0 (en) 2009-08-12

Family

ID=41008692

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0911566.8A Ceased GB0911566D0 (en) 2009-07-03 2009-07-03 T cell receptors

Country Status (19)

Country Link
US (2) US8519100B2 (enExample)
EP (1) EP2448963B1 (enExample)
JP (2) JP5872464B2 (enExample)
CN (3) CN102574906A (enExample)
AU (1) AU2010267758C1 (enExample)
BR (1) BR112012000107A2 (enExample)
CA (1) CA2766505C (enExample)
DK (1) DK2448963T3 (enExample)
EA (1) EA026918B1 (enExample)
ES (1) ES2498190T3 (enExample)
FI (1) FIC20220037I1 (enExample)
FR (1) FR22C1046I2 (enExample)
GB (1) GB0911566D0 (enExample)
LU (1) LUC00278I2 (enExample)
MX (1) MX2012000155A (enExample)
NL (1) NL301193I2 (enExample)
PT (1) PT2448963E (enExample)
WO (1) WO2011001152A1 (enExample)
ZA (1) ZA201109522B (enExample)

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US9181527B2 (en) 2009-10-29 2015-11-10 The Trustees Of Dartmouth College T cell receptor-deficient T cell compositions
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
US9833476B2 (en) 2011-08-31 2017-12-05 The Trustees Of Dartmouth College NKP30 receptor targeted therapeutics
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SI3464380T1 (sl) 2016-06-02 2025-03-31 Immunocore Limited Režim doziranja za gp100-specifični tcr - anti-cd3 scfv fuzijski protein
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JP2020501508A (ja) * 2016-09-15 2020-01-23 クアドルセプト バイオ リミテッド 多量体、四量体および八量体
GB201617714D0 (en) 2016-10-19 2016-11-30 Ucl Business Plc T Cell receptor
JP7037577B2 (ja) 2017-03-15 2022-03-16 フレッド ハッチンソン キャンサー リサーチ センター 高親和性ｍａｇｅ－ａ１特異的ｔｃｒ及びその使用
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MX2020003144A (es) * 2017-09-22 2020-07-28 Wuxi Biologics Ireland Ltd Nuevos complejos de polipeptidos biespecificos cd3/cd19.
KR102839644B1 (ko) 2017-09-22 2025-07-31 우시 바이올로직스 아일랜드 리미티드 신규한 이중특이적 폴리펩티드 복합체
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