GB0815264D0 - Non-cytotoxic proteins - Google Patents

Non-cytotoxic proteins

Info

Publication number
GB0815264D0
GB0815264D0 GBGB0815264.7A GB0815264A GB0815264D0 GB 0815264 D0 GB0815264 D0 GB 0815264D0 GB 0815264 A GB0815264 A GB 0815264A GB 0815264 D0 GB0815264 D0 GB 0815264D0
Authority
GB
United Kingdom
Prior art keywords
cytotoxic proteins
cytotoxic
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0815264.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntaxin Ltd
Original Assignee
Syntaxin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntaxin Ltd filed Critical Syntaxin Ltd
Priority to GBGB0815264.7A priority Critical patent/GB0815264D0/en
Publication of GB0815264D0 publication Critical patent/GB0815264D0/en
Priority to EP09785502.7A priority patent/EP2326665B1/en
Priority to PL09785502T priority patent/PL2326665T3/pl
Priority to DK09785502.7T priority patent/DK2326665T3/da
Priority to PT97855027T priority patent/PT2326665E/pt
Priority to US13/059,695 priority patent/US8614069B2/en
Priority to JP2011523457A priority patent/JP5658152B2/ja
Priority to ES09785502.7T priority patent/ES2436816T3/es
Priority to PCT/GB2009/051036 priority patent/WO2010020811A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GBGB0815264.7A 2008-08-21 2008-08-21 Non-cytotoxic proteins Ceased GB0815264D0 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
GBGB0815264.7A GB0815264D0 (en) 2008-08-21 2008-08-21 Non-cytotoxic proteins
EP09785502.7A EP2326665B1 (en) 2008-08-21 2009-08-19 Non-cytotoxic fusion proteins comprising egf muteins
PL09785502T PL2326665T3 (pl) 2008-08-21 2009-08-19 Niecytotoksyczne białka fuzyjne obejmujące muteinę EGF
DK09785502.7T DK2326665T3 (da) 2008-08-21 2009-08-19 Ikke-cytotoksiske fusionproteiner, omfattende egf-muteiner
PT97855027T PT2326665E (pt) 2008-08-21 2009-08-19 Proteínas de fusão não citotóxicas compreendendo muteínas de egf
US13/059,695 US8614069B2 (en) 2008-08-21 2009-08-19 Non-cytotoxic fusion proteins comprising EGF muteins
JP2011523457A JP5658152B2 (ja) 2008-08-21 2009-08-19 非細胞毒性融合タンパク質
ES09785502.7T ES2436816T3 (es) 2008-08-21 2009-08-19 Proteínas de fusión no citotóxicas que comprenden muteínas de EGF
PCT/GB2009/051036 WO2010020811A1 (en) 2008-08-21 2009-08-19 Non-cytotoxic fusion proteins comprising egf muteins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0815264.7A GB0815264D0 (en) 2008-08-21 2008-08-21 Non-cytotoxic proteins

Publications (1)

Publication Number Publication Date
GB0815264D0 true GB0815264D0 (en) 2008-09-24

Family

ID=39812369

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0815264.7A Ceased GB0815264D0 (en) 2008-08-21 2008-08-21 Non-cytotoxic proteins

Country Status (9)

Country Link
US (1) US8614069B2 (enExample)
EP (1) EP2326665B1 (enExample)
JP (1) JP5658152B2 (enExample)
DK (1) DK2326665T3 (enExample)
ES (1) ES2436816T3 (enExample)
GB (1) GB0815264D0 (enExample)
PL (1) PL2326665T3 (enExample)
PT (1) PT2326665E (enExample)
WO (1) WO2010020811A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9617671D0 (en) * 1996-08-23 1996-10-02 Microbiological Res Authority Recombinant toxin fragments
US8790897B2 (en) * 1998-08-25 2014-07-29 Syntaxin Ltd. Treatment of mucus hypersecretion
CN102083451A (zh) 2008-06-12 2011-06-01 赛恩泰新公司 癌症的抑制
WO2012061086A2 (en) * 2010-10-25 2012-05-10 Niiki Pharma Inc. Method of treating neuroendocrine tumors
KR101519118B1 (ko) * 2013-07-23 2015-05-12 (주)피앤피바이오팜 고안정성 상피세포 성장인자 변이체
CN107438620A (zh) 2015-03-31 2017-12-05 韦斯夸尔德有限公司 多肽
ES2913200T3 (es) 2015-03-31 2022-06-01 Sorriso Pharmaceuticals Inc Polipéptidos
WO2016156466A1 (en) * 2015-03-31 2016-10-06 Vhsquared Limited Peptide construct having a protease-cleavable linker
TW201814045A (zh) 2016-09-16 2018-04-16 英商艾普森生物製藥有限公司 製造雙鏈梭狀芽孢桿菌神經毒素之方法
US20210277071A1 (en) 2016-09-29 2021-09-09 Ipsen Biopharm Limited Hybrid neurotoxins
WO2018060453A1 (en) 2016-09-30 2018-04-05 Vhsquared Limited Compositions
EP3312290A1 (en) 2016-10-18 2018-04-25 Ipsen Biopharm Limited Cellular vamp cleavage assay
US11241480B2 (en) * 2017-01-26 2022-02-08 Washington University Methods for modulation of dietary and microbial exposure with compositions comprising an EGFR ligand
BR112020006827A2 (pt) 2018-01-29 2020-10-06 Ipsen Biopharm Limited neurotoxinas botulínicas clivando snare não neuronal
GB201815817D0 (en) * 2018-09-28 2018-11-14 Ispen Biopharm Ltd Clostridial neurotoxins comprising and exogenous activation loop
GB201900621D0 (en) * 2019-01-16 2019-03-06 Ipsen Biopharm Ltd Labelled polypeptides
WO2020219599A1 (en) * 2019-04-23 2020-10-29 Aurora Oncology Compositions and methods for treatment of distentable tissues
WO2020254827A1 (en) 2019-06-21 2020-12-24 Vhsquared Limited Polypeptides
CN114514243B (zh) 2019-06-21 2025-01-24 索瑞索制药公司 多肽
WO2024249812A2 (en) * 2023-06-01 2024-12-05 Blaze Bioscience, Inc. Egf variants and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8003A (en) * 1851-03-25 Improvement in scythe-tastenings
GB9818548D0 (en) * 1998-08-25 1998-10-21 Microbiological Res Authority Treatment of mucas hypersecretion
US8790897B2 (en) * 1998-08-25 2014-07-29 Syntaxin Ltd. Treatment of mucus hypersecretion
US20080038274A1 (en) * 1999-09-23 2008-02-14 Foster Keith A Inhibition of secretion from non-neuronal cells
US7037504B2 (en) * 2001-10-23 2006-05-02 Waratah Pharmaceuticals, Inc. Epidermal growth factor protein and gene, and methods of use therefor
CA2476006A1 (en) 2002-02-05 2003-08-14 Japan Science And Technology Agency Egf/egfr complex
WO2007109673A2 (en) 2006-03-20 2007-09-27 Stanford University Mutant epidermal growth factor polypeptides, nucleic acids, and uses therefor
GB0725321D0 (en) 2007-12-31 2008-02-06 Syntaxin Ltd Delivery vehicles

Also Published As

Publication number Publication date
US8614069B2 (en) 2013-12-24
EP2326665B1 (en) 2013-10-09
JP5658152B2 (ja) 2015-01-21
US20110177056A1 (en) 2011-07-21
EP2326665A1 (en) 2011-06-01
WO2010020811A1 (en) 2010-02-25
JP2012500018A (ja) 2012-01-05
PT2326665E (pt) 2013-12-23
PL2326665T3 (pl) 2014-03-31
DK2326665T3 (da) 2013-11-25
ES2436816T3 (es) 2014-01-07

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)