GB0031088D0 - Medicaments - Google Patents

Medicaments

Info

Publication number
GB0031088D0
GB0031088D0 GBGB0031088.8A GB0031088A GB0031088D0 GB 0031088 D0 GB0031088 D0 GB 0031088D0 GB 0031088 A GB0031088 A GB 0031088A GB 0031088 D0 GB0031088 D0 GB 0031088D0
Authority
GB
United Kingdom
Prior art keywords
medicaments
derivatives
mammals
man
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0031088.8A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Priority to GBGB0031088.8A priority Critical patent/GB0031088D0/en
Publication of GB0031088D0 publication Critical patent/GB0031088D0/en
Priority to JP2002551557A priority patent/JP2004518661A/ja
Priority to US10/450,884 priority patent/US20040077655A1/en
Priority to AU2002222287A priority patent/AU2002222287A1/en
Priority to AT01271369T priority patent/ATE340171T1/de
Priority to PCT/GB2001/005653 priority patent/WO2002050061A1/en
Priority to ES01271369T priority patent/ES2269301T3/es
Priority to DE60123276T priority patent/DE60123276T2/de
Priority to EP01271369A priority patent/EP1343780B1/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
GBGB0031088.8A 2000-12-20 2000-12-20 Medicaments Ceased GB0031088D0 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
GBGB0031088.8A GB0031088D0 (en) 2000-12-20 2000-12-20 Medicaments
JP2002551557A JP2004518661A (ja) 2000-12-20 2001-12-19 細菌感染の治療用ピペラジン誘導体
US10/450,884 US20040077655A1 (en) 2000-12-20 2001-12-19 Piperazine derivatives for treatment of bacterial infections
AU2002222287A AU2002222287A1 (en) 2000-12-20 2001-12-19 Piperazine derivatives for treatment of bacterial infections
AT01271369T ATE340171T1 (de) 2000-12-20 2001-12-19 Piperazinderivate zur behandlung bakterieller infektionen
PCT/GB2001/005653 WO2002050061A1 (en) 2000-12-20 2001-12-19 Piperazine derivatives for treatment of bacterial infections
ES01271369T ES2269301T3 (es) 2000-12-20 2001-12-19 Derivados de piperazina para tratamiento de infecciones bacterianas.
DE60123276T DE60123276T2 (de) 2000-12-20 2001-12-19 Piperazinderivate zur behandlung bakterieller infektionen
EP01271369A EP1343780B1 (en) 2000-12-20 2001-12-19 Piperazine derivatives for treatment of bacterial infections

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0031088.8A GB0031088D0 (en) 2000-12-20 2000-12-20 Medicaments

Publications (1)

Publication Number Publication Date
GB0031088D0 true GB0031088D0 (en) 2001-01-31

Family

ID=9905481

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0031088.8A Ceased GB0031088D0 (en) 2000-12-20 2000-12-20 Medicaments

Country Status (9)

Country Link
US (1) US20040077655A1 (enExample)
EP (1) EP1343780B1 (enExample)
JP (1) JP2004518661A (enExample)
AT (1) ATE340171T1 (enExample)
AU (1) AU2002222287A1 (enExample)
DE (1) DE60123276T2 (enExample)
ES (1) ES2269301T3 (enExample)
GB (1) GB0031088D0 (enExample)
WO (1) WO2002050061A1 (enExample)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
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GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
JP2004504397A (ja) 2000-07-26 2004-02-12 スミスクライン ビーチャム パブリック リミテッド カンパニー 抗菌活性を有するアミノピペリジンキノリン類およびそれらのアザイソステリックアナログ類
EP1320529B1 (en) * 2000-09-21 2006-05-24 Smithkline Beecham Plc Quinoline derivatives as antibacterials
GB0031086D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) * 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112834D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
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ATE449090T1 (de) * 2001-07-02 2009-12-15 High Point Pharmaceuticals Llc Substituierte piperazin- und diazepanderivate zur verwendung als histamin h3 rezeptormodulatoren
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TW200507841A (en) * 2003-03-27 2005-03-01 Glaxo Group Ltd Antibacterial agents
CN100471856C (zh) * 2003-07-31 2009-03-25 Irm责任有限公司 作为pdf抑制剂的二环化合物和组合物
EP1784410A4 (en) * 2004-08-09 2009-07-15 Glaxo Group Ltd ANTIBACTERIAL AGENTS
JP5118975B2 (ja) * 2004-12-24 2013-01-16 アストラゼネカ・アクチエボラーグ Ccr2bアンタゴニストとしてのヘテロ環式化合物
GB0428327D0 (en) * 2004-12-24 2005-02-02 Astrazeneca Ab Method
DK1836179T3 (en) * 2004-12-30 2015-05-26 Janssen Pharmaceutica Nv PIPERIDINE AND PIPERAZINE-1-CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF FAT ACID AMIDE HYDRALASE (FAAH) FOR THE TREATMENT OF ANCIENT, PAIN AND OTHER CONDITIONS
WO2006081289A2 (en) 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
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WO2006081264A1 (en) 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
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JP4902247B2 (ja) * 2005-04-08 2012-03-21 富山化学工業株式会社 2−(1−ベンゾチオフェン−5−イル)エタノールの新規製造法およびその中間体
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WO2007100880A1 (en) * 2006-02-28 2007-09-07 Amgen Inc. Cinnoline and quinazoline derivates as phosphodiesterase 10 inhibitors
MX2008011257A (es) * 2006-03-08 2008-09-25 Amgen Inc Derivados de quinolina e isoquinolina como inhibidores de fosfodiesterasa 10.
DE602007009205D1 (de) 2006-04-06 2010-10-28 Glaxo Group Ltd Pyrrolochinoxalinonderivate als antibakterielle mittel
EP2007377A4 (en) 2006-04-06 2011-08-17 Glaxo Group Ltd ANTIBACTERIAL ACTIVE SUBSTANCES
AU2007268749B2 (en) 2006-05-26 2012-07-26 Taisho Pharmaceutical Co., Ltd. Novel heterocyclic compound or salt thereof and intermediate thereof
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
WO2008128942A1 (en) * 2007-04-20 2008-10-30 Glaxo Group Limited Tricyclic nitrogen containing compounds as antibacterial agents
PL2221309T3 (pl) 2007-11-26 2013-12-31 Toyama Chemical Co Ltd Monohydrat pochodnej naftyrydyny i sposób jego wytwarzania
EP2080761A1 (en) 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
JP2012505866A (ja) 2008-10-17 2012-03-08 グラクソ グループ リミテッド 抗菌剤として使用される三環式窒素化合物
JP5653935B2 (ja) 2009-01-15 2015-01-14 グラクソ グループ リミテッドGlaxo Group Limited 抗菌薬として有用なナフチリジン―2(1h)−オン化合物
US8673920B2 (en) 2009-05-06 2014-03-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2011026241A1 (en) * 2009-09-04 2011-03-10 Zalicus Pharmaceuticals Ltd. Substituted heterocyclic derivatives for the treatment of pain and epilepsy
WO2012058116A1 (en) 2010-10-27 2012-05-03 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9056859B2 (en) 2010-10-29 2015-06-16 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
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KR20140052034A (ko) 2011-08-19 2014-05-02 머크 샤프 앤드 돔 코포레이션 신장 외수질 칼륨 채널의 억제제
EP2755656B1 (en) 2011-09-16 2016-09-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2013062900A1 (en) 2011-10-25 2013-05-02 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
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US9493474B2 (en) 2011-10-31 2016-11-15 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2013066714A1 (en) 2011-10-31 2013-05-10 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2773206B1 (en) 2011-10-31 2018-02-21 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
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GB201218850D0 (en) 2012-10-19 2012-12-05 Astex Therapeutics Ltd Bicyclic heterocycle compounds and their uses in therapy
US9777002B2 (en) 2012-11-29 2017-10-03 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9573961B2 (en) 2012-12-19 2017-02-21 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9604998B2 (en) 2013-02-18 2017-03-28 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US10208023B2 (en) 2013-03-01 2019-02-19 Mark G. DeGiacomo Heterocyclic inhibitors of the sodium channel
WO2014150132A1 (en) 2013-03-15 2014-09-25 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
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Also Published As

Publication number Publication date
DE60123276T2 (de) 2007-09-27
WO2002050061A1 (en) 2002-06-27
WO2002050061A8 (en) 2002-07-25
DE60123276D1 (de) 2006-11-02
AU2002222287A1 (en) 2002-07-01
US20040077655A1 (en) 2004-04-22
ES2269301T3 (es) 2007-04-01
EP1343780B1 (en) 2006-09-20
ATE340171T1 (de) 2006-10-15
EP1343780A1 (en) 2003-09-17
JP2004518661A (ja) 2004-06-24

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)