FR2974364B1 - Nouveaux derives amino-pyrroliniques, leur utilisation dans la prevention et/ou le traitement du syndrome metabolique - Google Patents

Nouveaux derives amino-pyrroliniques, leur utilisation dans la prevention et/ou le traitement du syndrome metabolique

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Publication number
FR2974364B1
FR2974364B1 FR1153375A FR1153375A FR2974364B1 FR 2974364 B1 FR2974364 B1 FR 2974364B1 FR 1153375 A FR1153375 A FR 1153375A FR 1153375 A FR1153375 A FR 1153375A FR 2974364 B1 FR2974364 B1 FR 2974364B1
Authority
FR
France
Prior art keywords
prevention
treatment
derivatives
metabolic syndrome
pyrrolinic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1153375A
Other languages
English (en)
Other versions
FR2974364A1 (fr
Inventor
Pascal Bousquet
Jean Daniel Erhardt
Lyne Fellmann
Vincent Gasparik
Hugues Greney
Mohamed Hadjeri
Andre Mann
Nathalie Niederhoffer
Stephan Schann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Strasbourg
Original Assignee
Universite de Strasbourg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1153375A priority Critical patent/FR2974364B1/fr
Application filed by Universite de Strasbourg filed Critical Universite de Strasbourg
Priority to PCT/FR2012/050835 priority patent/WO2012143660A1/fr
Priority to RS20160689A priority patent/RS55061B1/sr
Priority to PT127224236T priority patent/PT2699545T/pt
Priority to DK12722423.6T priority patent/DK2699545T3/en
Priority to JP2014505700A priority patent/JP5986625B2/ja
Priority to CN201280019520.6A priority patent/CN103619814B/zh
Priority to CA2833339A priority patent/CA2833339C/fr
Priority to EP12722423.6A priority patent/EP2699545B1/fr
Priority to US14/112,631 priority patent/US9303019B2/en
Priority to LTEP12722423.6T priority patent/LT2699545T/lt
Priority to HUE12722423A priority patent/HUE030432T2/en
Priority to PL12722423T priority patent/PL2699545T3/pl
Priority to ES12722423.6T priority patent/ES2588059T3/es
Priority to SI201230681A priority patent/SI2699545T1/sl
Publication of FR2974364A1 publication Critical patent/FR2974364A1/fr
Publication of FR2974364B1 publication Critical patent/FR2974364B1/fr
Application granted granted Critical
Priority to HRP20161024TT priority patent/HRP20161024T1/hr
Priority to CY20161100829T priority patent/CY1118117T1/el
Priority to SM201600284T priority patent/SMT201600284B/it
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Nouveaux dérivés amino-pyrroliniques, leurs sels pharmacologiquement acceptables et leur utilisation dans la prévention et/ou le traitement du syndrome métabolique.
FR1153375A 2011-04-19 2011-04-19 Nouveaux derives amino-pyrroliniques, leur utilisation dans la prevention et/ou le traitement du syndrome metabolique Expired - Fee Related FR2974364B1 (fr)

Priority Applications (18)

Application Number Priority Date Filing Date Title
FR1153375A FR2974364B1 (fr) 2011-04-19 2011-04-19 Nouveaux derives amino-pyrroliniques, leur utilisation dans la prevention et/ou le traitement du syndrome metabolique
PL12722423T PL2699545T3 (pl) 2011-04-19 2012-04-17 Nowe pochodne aminopirolinowe, ich zastosowanie w zapobieganiu i/lub leczeniu zespołu metabolicznego
RS20160689A RS55061B1 (sr) 2011-04-19 2012-04-17 Novi derivati amino-pirolina i njihova upotreba u prevenciji i/ili lečenju metaboličkog sindroma
DK12722423.6T DK2699545T3 (en) 2011-04-19 2012-04-17 NEW AMINO-pyrrolidine, AND USE THEREOF IN PREVENTION AND / OR TREATMENT OF metabolic syndrome
JP2014505700A JP5986625B2 (ja) 2011-04-19 2012-04-17 新規のアミノピロリン誘導体、ならびにメタボリックシンドロームの予防および／または治療におけるその使用
CN201280019520.6A CN103619814B (zh) 2011-04-19 2012-04-17 氨基-吡咯啉衍生物及其在预防和/或治疗代谢综合征中的用途
CA2833339A CA2833339C (fr) 2011-04-19 2012-04-17 Nouveaux derives amino-pyrroliniques, leur utilisation dans la prevention et/ou le traitement du syndrome metabolique
EP12722423.6A EP2699545B1 (fr) 2011-04-19 2012-04-17 Nouveaux derives amino-pyrroliniques, leur utilisation dans la prevention et/ou le traitement du syndrome metabolique
ES12722423.6T ES2588059T3 (es) 2011-04-19 2012-04-17 Nuevos derivados amino-pirrolínicos, su utilización en la prevención y/o tratamiento del síndrome metabólico
LTEP12722423.6T LT2699545T (lt) 2011-04-19 2012-04-17 Nauji amino-pirolino dariniai ir jų naudojimas metabolinio sindromo prevencijai ir (arba) gydymui
PCT/FR2012/050835 WO2012143660A1 (fr) 2011-04-19 2012-04-17 Nouveaux derives amino-pyrroliniques, leur utilisation dans la prevention et/ou le traitement du syndrome metabolique
PT127224236T PT2699545T (pt) 2011-04-19 2012-04-17 Novos derivados amino-pirrolínicos, sua utilização na prevenção e/ou tratamento do síndrome metabólico
US14/112,631 US9303019B2 (en) 2011-04-19 2012-04-17 Amino-pyrroline derivatives, and use thereof in the prevention and/or treatment of metabolic syndrome
SI201230681A SI2699545T1 (sl) 2011-04-19 2012-04-17 Novi amino-pirolinski derivati in uporaba le-teh pri preprečevanju in/ali zdravljenju metaboličnega sindroma
HUE12722423A HUE030432T2 (en) 2011-04-19 2012-04-17 New amino pyrrolines, their use in the prevention and treatment of metabolic syndrome
HRP20161024TT HRP20161024T1 (hr) 2011-04-19 2016-08-16 Novi derivati amino-pirolina i njihova uporaba u sprječavanju i/ili liječenju metaboličkog sindroma
CY20161100829T CY1118117T1 (el) 2011-04-19 2016-08-22 Νεα αμινο-πυρρολινικα παραγωγα και η χρηση τους στην προληψη ή και τη θεραπεια του μεταβολικου συνδρομου
SM201600284T SMT201600284B (it) 2011-04-19 2016-08-23 Nuovi derivati di ammino-pirrolina, e loro usi nella prevenzione e/o nel trattamento della sindrome metabolica

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1153375A FR2974364B1 (fr) 2011-04-19 2011-04-19 Nouveaux derives amino-pyrroliniques, leur utilisation dans la prevention et/ou le traitement du syndrome metabolique

Publications (2)

Publication Number Publication Date
FR2974364A1 FR2974364A1 (fr) 2012-10-26
FR2974364B1 true FR2974364B1 (fr) 2013-10-11

Family

ID=44534837

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1153375A Expired - Fee Related FR2974364B1 (fr) 2011-04-19 2011-04-19 Nouveaux derives amino-pyrroliniques, leur utilisation dans la prevention et/ou le traitement du syndrome metabolique

Country Status (1)

Country Link
FR (1) FR2974364B1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2015007710A (es) * 2012-12-19 2015-09-23 Bayer Cropscience Ag Indanilcarboxamidas difluorometil-nicotinicas.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679692A (en) * 1969-10-01 1972-07-25 Mead Johnson & Co Iminomethylindolines
BE757934A (fr) * 1969-10-23 1971-04-23 Bayer Ag Nouvelles 2-phenylamino-delta 1-pyrrolines et leur application comme acaricides
US4579951A (en) * 1984-03-19 1986-04-01 G. D. Searle & Co. Substituted (azacycloalk-2-yl)iminophenols and esters thereof
CA2777223C (fr) * 2009-10-06 2017-10-24 Allergan, Inc. Derives de 2h-pyrrol-5-amine utilises en tant que modulateurs des recepteurs alpha-adrenergiques
US20120238615A1 (en) * 2009-10-21 2012-09-20 Allergan, Inc. Alpha adrenergic receptor modulators

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Publication number Publication date
FR2974364A1 (fr) 2012-10-26

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