FR2937972B1 - Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique - Google Patents

Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique

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Publication number
FR2937972B1
FR2937972B1 FR0857496A FR0857496A FR2937972B1 FR 2937972 B1 FR2937972 B1 FR 2937972B1 FR 0857496 A FR0857496 A FR 0857496A FR 0857496 A FR0857496 A FR 0857496A FR 2937972 B1 FR2937972 B1 FR 2937972B1
Authority
FR
France
Prior art keywords
cosmetics
preparation
human medicine
oxoazetidine derivatives
oxoazetidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0857496A
Other languages
English (en)
French (fr)
Other versions
FR2937972A1 (fr
Inventor
Peter Claire Bouix
Itaru Suzuki
Nicolas Rodeville
Pascale Mauvais
Jean Claude Pascal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma Research and Development SNC
Original Assignee
Galderma Research and Development SNC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0857496A priority Critical patent/FR2937972B1/fr
Application filed by Galderma Research and Development SNC filed Critical Galderma Research and Development SNC
Priority to CN201410498368.5A priority patent/CN104387372B/zh
Priority to ARP090104265A priority patent/AR074275A1/es
Priority to RU2015141009A priority patent/RU2671189C1/ru
Priority to EP09744417.8A priority patent/EP2342194B1/en
Priority to CN2009801446981A priority patent/CN102203081A/zh
Priority to KR1020117012910A priority patent/KR101689042B1/ko
Priority to JP2011533761A priority patent/JP5798486B2/ja
Priority to RU2011122637/04A priority patent/RU2569886C2/ru
Priority to AU2009312818A priority patent/AU2009312818B2/en
Priority to CA2738785A priority patent/CA2738785C/en
Priority to PCT/EP2009/064646 priority patent/WO2010052253A1/en
Priority to US13/127,643 priority patent/US8871187B2/en
Priority to MX2011004068A priority patent/MX2011004068A/es
Priority to BRPI0916069A priority patent/BRPI0916069C1/pt
Publication of FR2937972A1 publication Critical patent/FR2937972A1/fr
Application granted granted Critical
Publication of FR2937972B1 publication Critical patent/FR2937972B1/fr
Priority to US14/497,600 priority patent/US9630949B2/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
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    • A61P9/12—Antihypertensives
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    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
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    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
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    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/008—Preparations for oily skin
    • A—HUMAN NECESSITIES
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    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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FR0857496A 2008-11-04 2008-11-04 Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique Expired - Fee Related FR2937972B1 (fr)

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Application Number Priority Date Filing Date Title
FR0857496A FR2937972B1 (fr) 2008-11-04 2008-11-04 Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
CA2738785A CA2738785C (en) 2008-11-04 2009-11-04 Oxoazetidine derivatives, process for the preparation thereof and use thereof in human medicine and in cosmetics
RU2015141009A RU2671189C1 (ru) 2008-11-04 2009-11-04 Производные оксоазетидина, способ их получения и их применения в медицине и косметологии
EP09744417.8A EP2342194B1 (en) 2008-11-04 2009-11-04 Oxoazetidine derivatives, process for the preparation thereof and use thereof in human medicine and in cosmetics
CN2009801446981A CN102203081A (zh) 2008-11-04 2009-11-04 氧代吖丁啶衍生物、其制备方法及其在人类医药和美容品中的用途
KR1020117012910A KR101689042B1 (ko) 2008-11-04 2009-11-04 옥소아제티딘 유도체, 이의 제조 방법 및 인간 약물 및 화장품에서의 이의 용도
JP2011533761A JP5798486B2 (ja) 2008-11-04 2009-11-04 オキソアゼチジン誘導体、その調製方法、ならびにヒト医薬および化粧品におけるその使用
RU2011122637/04A RU2569886C2 (ru) 2008-11-04 2009-11-04 Производные оксоазетидина, способ их получения и их применения в медицине и косметологии
CN201410498368.5A CN104387372B (zh) 2008-11-04 2009-11-04 氧代吖丁啶衍生物、其制备方法及其在人类医药和美容品中的用途
ARP090104265A AR074275A1 (es) 2008-11-04 2009-11-04 Derivados de oxoacetidina, procedimiento para su preparacion y su uso como moduladores de la melanocortina
PCT/EP2009/064646 WO2010052253A1 (en) 2008-11-04 2009-11-04 Oxoazetidine derivatives, process for the preparation thereof and use thereof in human medicine and in cosmetics
US13/127,643 US8871187B2 (en) 2008-11-04 2009-11-04 Oxoazetidine derivatives, process for the preparation thereof and use thereon in human medicine and in cosmetics
MX2011004068A MX2011004068A (es) 2008-11-04 2009-11-04 Derivados de oxoazetidina, procesos para la preparacion de los mismos y usos de los mismos en medicina humana y en cosmeticos.
BRPI0916069A BRPI0916069C1 (pt) 2008-11-04 2009-11-04 composto, usos de um composto, composição farmacêutica, composição cosmética e usos cosméticos de uma composição
AU2009312818A AU2009312818B2 (en) 2008-11-04 2009-11-04 Oxoazetidine derivatives, process for the preparation thereof and use thereof in human medicine and in cosmetics
US14/497,600 US9630949B2 (en) 2008-11-04 2014-09-26 Oxoazetidine derivatives, process for the preparation thereof and use thereof in human medicine and in cosmetics

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FR0857496A FR2937972B1 (fr) 2008-11-04 2008-11-04 Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique

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CA (1) CA2738785C (enExample)
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FR2939135B1 (fr) * 2008-12-02 2010-12-03 Galderma Res & Dev Nouveaux composes 4-(azacycloalkyl)-benzene-1,3-diol comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
FR2969494B1 (fr) * 2010-12-22 2013-11-08 Expanscience Lab Extrait de parties aeriennes de gynandropsis gynandra ou cleome gynandra et compositions cosmetiques, dermatologiques le comprenant
FR2981933B1 (fr) * 2011-11-02 2013-11-15 Galderma Res & Dev Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
FR2984167B1 (fr) * 2011-12-16 2014-01-17 Galderma Res & Dev Association d'un agoniste des recepteurs des prostaglandines et d'un agoniste du recepteur mc1r pour le traitement et/ou la prevention de desordres de la pigmentation
EP2825187A1 (en) 2012-03-15 2015-01-21 Galderma Research & Development Combination of a mc1r receptor agonist and uvb for the treatment and/or prevention of pigmentation disorders
FR2992317B1 (fr) 2012-06-22 2016-05-13 Diverchim Procede de preparation de peptides chiraux
FR3027900B1 (fr) 2014-11-05 2018-02-23 Centre National De La Recherche Scientifique Utilisation de derives halogenes de l'histidine a titre de sel d'electrolyte dans une cellule photovoltaique a colorants
CA3252823A1 (en) 2016-06-13 2025-02-25 Gilead Sciences Inc Fxr (nr1h4) modulating compounds
SI3730487T1 (sl) 2016-06-13 2022-08-31 Gilead Sciences, Inc. Azetidinski derivati kot modulatorji FXR (NR1H4)
WO2018142318A1 (en) * 2017-02-01 2018-08-09 Clinuvel Pharmaceuticals Ltd Alpha-msh analogues used in the treatment of xeroderma pigmentosum
JP6906626B2 (ja) 2017-03-28 2021-07-21 ギリアード サイエンシーズ， インコーポレイテッド 肝疾患を処置するための治療的組み合わせ
EP3927683A1 (en) 2019-02-19 2021-12-29 Gilead Sciences, Inc. Solid forms of fxr agonists
WO2022056494A1 (en) 2020-09-14 2022-03-17 Regeneron Pharmaceuticals, Inc. Antibody-drug conjugates comprising glp1 peptidomimetics and uses thereof
JP2025512735A (ja) 2022-03-11 2025-04-22 リジェネロン ファーマシューティカルズ，インク． Ｇｌｐ１ペプチド模倣体を含む抗ｇｌｐ１ｒ抗体係留型薬物コンジュゲートおよびその使用

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US6720001B2 (en) 1999-10-18 2004-04-13 Lipocine, Inc. Emulsion compositions for polyfunctional active ingredients
US6399651B1 (en) 2000-06-29 2002-06-04 L. Dean Parks Method of treating dermatoses using avermectin compound
JP2005511475A (ja) * 2001-03-02 2005-04-28 ブリストル−マイヤーズ スクイブ カンパニー メラノコルチン受容体のモジュレーターとして有用な化合物及びそれを含む製薬組成物
HUP0600103A2 (en) * 2001-03-02 2006-06-28 Bristol Myers Squibb Co Co-administration of melanocortin receptor agonist and phosphodiesterase inhibitor for treatment of cyclic-amp associated disorders
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EP2342194B1 (en) 2018-08-08
AR074275A1 (es) 2011-01-05
MX2011004068A (es) 2011-05-31
JP5798486B2 (ja) 2015-10-21
WO2010052253A1 (en) 2010-05-14
US20150045559A1 (en) 2015-02-12
KR20110088555A (ko) 2011-08-03
RU2011122637A (ru) 2012-12-20
FR2937972A1 (fr) 2010-05-07
KR101689042B1 (ko) 2016-12-22
JP2012507491A (ja) 2012-03-29
RU2671189C1 (ru) 2018-10-30
CN104387372B (zh) 2018-06-26
CN102203081A (zh) 2011-09-28
CA2738785C (en) 2017-05-16
US8871187B2 (en) 2014-10-28
US20110274638A1 (en) 2011-11-10
BRPI0916069B8 (pt) 2019-12-17
AU2009312818A1 (en) 2010-05-14
CA2738785A1 (en) 2010-05-14
AU2009312818B2 (en) 2014-11-06
BRPI0916069C1 (pt) 2021-05-25
US9630949B2 (en) 2017-04-25
EP2342194A1 (en) 2011-07-13
RU2569886C2 (ru) 2015-12-10
CN104387372A (zh) 2015-03-04
BRPI0916069A2 (pt) 2015-11-10

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